Azithromycin+fluconazole+ornidazole
About Azithromycin+fluconazole+ornidazole
Azithromycin+fluconazole+ornidazole is a prescription medicine used to treat mixed infections of the reproductive tract, such as pelvic inflammatory disease and vaginal discharge. It targets several types of disease-causing organisms simultaneously, including bacteria, fungi, and parasites, to clear up complex genital tract infections.
Because it is typically prescribed as a short-course or single-day treatment kit, taking it exactly as directed is crucial for complete healing. You should take the tablets with food to protect your stomach from irritation. Wearing breathable clothing and practising good personal hygiene will also support your recovery during treatment.
Most people tolerate this medicine well, though some may experience temporary side effects like nausea or a metallic taste in the mouth. If you experience severe abdominal pain, persistent vomiting, or yellowing of the skin or eyes, stop taking the medicine and consult your doctor immediately.
Talk to your doctor before taking Azithromycin+fluconazole+ornidazole if you have liver disease, kidney problems, nervous system disorders, myasthenia gravis, or heart rhythm problems, including QT prolongation (a type of irregular heart rhythm that can be serious). Tell your doctor if you are taking medicines that affect your heart rhythm. Do not take this medicine if you are allergic to any of its active ingredients or related antifungal or antibacterial medicines.
This medicine can interact with blood thinners and certain seizure medicines, potentially altering how they work. Avoid all forms of alcohol during treatment and for at least 72 hours after your last dose to prevent a severe stomach reaction. If you are pregnant or breastfeeding, consult your doctor before taking this medicine. Some of its active ingredients may pass into breast milk, and your doctor will decide whether this medicine is suitable for you.
This medicine should only be used in children and adolescents if prescribed by a doctor. If you are an older adult or have other health conditions, consult your doctor before using this medicine.
Uses of Azithromycin+fluconazole+ornidazole
Medicinal Benefits
Azithromycin+fluconazole+ornidazole offers several benefits in treating mixed infections of the genital and urinary tracts, including:
- Broad-Spectrum Approach: Azithromycin+fluconazole+ornidazole targets a wide range of bacteria, fungi, and parasites, making it effective for treating mixed infections.
- Convenient Treatment: Because mixed infections involve multiple types of organisms, this combination medicine eliminates the need to take several different medicines over long periods, offering a convenient and streamlined treatment option.
- Symptom Relief and Prevention of Complications: Patients typically experience rapid relief from distressing symptoms like pelvic discomfort, burning during urination, irritation, and abnormal discharge. By quickly clearing the underlying infection, it helps prevent serious long-term complications, such as pelvic scarring or future reproductive health issues.
Directions for Use
- Azithromycin+fluconazole+ornidazole can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow it as a whole with a glass of water.
- Do not chew, crush or break it.
Storage
Side Effects of Azithromycin+fluconazole+ornidazole
Common Side Effects (Usually mild):
- Nausea or vomiting
- Upset stomach or mild diarrhoea
- A temporary metallic or unusual taste in the mouth
- Mild headache or dizziness
Serious Side Effects (Consult your doctor right away):
- Signs of a severe allergic reaction (such as skin hives, swelling of the face, lips, or throat, and difficulty breathing)
- Severe, watery, or bloody diarrhoea with stomach cramps
- Yellowing of the skin or eyes, which may indicate liver damage
- Numbness, tingling, or a burning sensation in your hands or feet
- Fast or irregular heartbeat, dizziness, or fainting (QT prolongation)
Medicines Containing this Salt
View AllDrug Warnings
- Complete the full course: Even if your symptoms clear up within 24 hours, take all the pills in the kit to prevent the infection from returning or becoming resistant.
- Do not consume alcohol: Strictly avoid alcohol while taking this medicine and for at least 72 hours after your last dose, as mixing them can cause severe vomiting, rapid heart rate, and chest pain.
- Inspect the packaging: Do not take any tablets if the blister foil is torn, punctured, or shows signs of tampering.
- Do not share this medicine: This kit is specifically selected for your current infection and should never be shared with others.
- Report nerve tingling immediately: Stop taking the medicine and contact your doctor if you experience any unexpected numbness, tingling, or weakness in your limbs.
- Follow-up: Contact your doctor if your symptoms do not improve, worsen, or return after completing treatment, as further evaluation or additional treatment may be required.
Drug Interactions
The following medicines may interact with Azithromycin+fluconazole+ornidazole and affect how it works or increase the risk of side effects:
- Warfarin (blood thinners): Taking Azithromycin+fluconazole+ornidazole with blood thinners like warfarin can increase your risk of bruising or bleeding.
- Phenytoin (seizure medicine): Combining this medicine with certain seizure treatments, such as phenytoin, can raise the levels of those medicines in your blood, increasing the risk of side effects.
- Medicines that affect heart rhythm: Using it alongside medicines that affect your heart rhythm can increase the risk of serious irregular heartbeats.
- Statins (cholesterol-lowering medicines): Taking this medicine with certain statins may increase the risk of muscle-related side effects.
- Sulfonylureas (a type of medicine used to manage blood sugar in diabetes): Taking this medicine with sulfonylureas may increase the risk of low blood sugar.
- Cyclosporine (used to prevent organ rejection or treat certain immune conditions): Taking this medicine with cyclosporine may increase cyclosporine levels in the blood and increase the risk of side effects.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption with Azithromycin+fluconazole+ornidazole as it may cause adverse effects such as nausea, increased heartbeat, chest pain, thirst, flushing (reddening of the skin), or low blood pressure. Please consult a doctor before consuming alcohol while using Azithromycin+fluconazole+ornidazole.
Pregnancy
cautionAzithromycin+fluconazole+ornidazole is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor before taking Azithromycin+fluconazole+ornidazole.
Breast Feeding
cautionIt is unknown whether Azithromycin+fluconazole+ornidazole is excreted in human milk. Azithromycin+fluconazole+ornidazole is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.
Driving
cautionAzithromycin+fluconazole+ornidazole may cause drowsiness, dizziness, or light-headedness. Therefore, avoid driving if you experience any of these symptoms after taking Azithromycin+fluconazole+ornidazole.
Liver
cautionAzithromycin+fluconazole+ornidazole should be used with caution in patients with liver disease. A dose adjustment of Azithromycin+fluconazole+ornidazole may be needed. Please consult your doctor before taking Azithromycin+fluconazole+ornidazole.
Kidney
cautionAzithromycin+fluconazole+ornidazole is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor before taking Azithromycin+fluconazole+ornidazole. Caution to be advised in patients with impaired renal function.
Children
cautionAzithromycin+fluconazole+ornidazole should be used with caution and in doses only as prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Wear breathable fabrics: Choose loose-fitting cotton underwear to keep the area dry, as moisture can encourage the growth of yeast and bacteria.
- Avoid scented products: Do not use scented body washes, douches, or feminine hygiene sprays, which can irritate your skin and disrupt natural healthy bacteria.
- Stay well hydrated: Drink plenty of water throughout the day to support your body’s natural healing processes.
- Ensure partner treatment: To prevent reinfection, your sexual partner may also need to be evaluated and treated by a doctor at the exact same time.
- Avoid intimate contact: Do not engage in sexual activity until you and your partner have fully completed the treatment and all symptoms have resolved.
Special Advise
- Avoid consuming alcohol while taking medication, as it may cause increased side effects.
- Azithromycin+fluconazole+ornidazole causes diarrhoea as a side effect. So drink plenty of fluids.
- Azithromycin+fluconazole+ornidazole must be taken at least 1 hour before or 2 hours after the antacids.
Patients Concern
Disease/Condition Glossary
Vaginal infection: Vaginal infection occurs at the vagina and tissues at the opening of the vagina. Vaginal infection caused by bacteria, yeast, and trichomoniasis. Symptoms include itching and irritation in the vagina and vulva, a burning sensation (especially during intercourse or while urinating), redness, and swelling of the vulva, vaginal pain, soreness, vaginal rash, thick/white, odour-free vaginal discharge with a cottage cheese appearance, watery vaginal discharge.
FAQs
Azithromycin+fluconazole+ornidazole is used to treat vaginal infections.
Azithromycin+fluconazole+ornidazole is a combination of three drugs, namely: Azithromycin (antibiotic), Fluconazole (antifungal) and Ornidazole (antiprotozoal). Azithromycin stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Fluconazole belongs to the class of antifungals that works by damaging the fungal cell membranes and kills fungi. Ornidazole belongs to the class of antiprotozoals that works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, kills micro-organisms and clears the infection.
Azithromycin+fluconazole+ornidazole cause common side effects like taste change, vomiting, headache, dizziness, stomach pain, nausea, indigestion, diarrhoea, loss of appetite. Most of these side effects of Azithromycin+fluconazole+ornidazole do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
Do not stop Azithromycin+fluconazole+ornidazole suddenly, finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
Azithromycin+fluconazole+ornidazole may be used to treat bacterial infections. Azithromycin+fluconazole+ornidazole contains Ornidazole, an antiprotozoal drug that kills bacteria, and protozoa and it also contains azithromycin, an antibiotic drug that kills bacteria.
Yes, the use of Azithromycin+fluconazole+ornidazole can cause diarrhoea. In the case of diarrhoea, drink plenty of water or other fluids. Talk to your doctor if diarrhoea persists and you notice any signs of dehydration, like less urination with dark-coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.
No, a higher dose of the Azithromycin+fluconazole+ornidazole than the recommended dose does not show more effectiveness. Instead, it can lead to negative consequences and make your health status more severe to recover.
Store Azithromycin+fluconazole+ornidazole by keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, place it in a plastic bag and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.
Discuss your symptoms with your doctor if you don't feel better after using Azithromycin+fluconazole+ornidazole. They may reassess your condition, adjust the dosage, or consider alternative treatments, as the infection may be resistant to the antibiotic. Healing is a gradual process that varies from person to person, depending on individual condition, dose, and body response to medication. Don't hesitate to consult your doctor with concerns or questions.
Don't stop taking your medication just because you're feeling better! Stopping too soon can lead to incomplete recovery and the return of symptoms. Instead, report your progress to your doctor and follow their advice. Your doctor will guide you on safely stopping the medication if needed, monitor for potential side effects, and ensure the infection is fully cleared.
To take Azithromycin+fluconazole+ornidazole, swallow the tablet whole with water. Do not crush, break, or chew it. Follow your doctor's instructions regarding dose and duration, and be sure to complete the full course as prescribed.
Generally, Azithromycin+fluconazole+ornidazole is unsafe to use during pregnancy without doctor guidance as there is definite evidence of risk to the developing baby. However, doctors may rarely prescribe it in life-threatening situations if the benefits outweigh the potential risks.
Yes, Azithromycin+fluconazole+ornidazole is an antibiotic medication, precisely a combination of three antibiotics: Azithromycin, Fluconazole, and Ornidazole.
Azithromycin+fluconazole+ornidazole is generally safe when used as directed. However, like all medications, it may lead to potential side effects and risks, especially if not used correctly. The level of risk varies depending on individual factors, such as medical history and health conditions. To minimize risks, follow your doctor's instructions and inform them of any pre-existing medical conditions or medication history. Don't hesitate to consult your doctor with concerns or questions.
No, you must avoid alcohol during treatment and for at least 72 hours after your last dose. Combining them can trigger a severe reaction, leading to intense vomiting, a rapid heartbeat, and severe headaches. Seek medical advice if you have any concerns.
Yes, if you are being treated for a sexually transmitted or mixed vaginal infection, your partner should also be evaluated and treated to prevent reinfecting you. Your doctor can advise whether your partner also needs treatment.
A temporary metallic taste is a very common and harmless side effect of one of the active ingredients in Azithromycin+fluconazole+ornidazole. It will go away naturally once you complete the treatment. Speak to your doctor or pharmacist if it becomes troublesome.
No, it is highly recommended to take Azithromycin+fluconazole+ornidazole with or immediately after food. This protects your stomach lining and helps reduce side effects like nausea or cramping. Seek medical advice if stomach discomfort persists.
If your symptoms return, do not buy another kit or take leftover medicine. The returning symptoms could be due to a different type of infection that requires a different treatment. See your doctor for further evaluation and appropriate treatment.
While many broad-spectrum antibiotics can trigger a yeast infection, Azithromycin+fluconazole+ornidazole contains a built-in antifungal component specifically designed to prevent and treat yeast infections. Seek medical advice if your symptoms persist or worsen.

