Ceftaroline Fosamil

Ceftaroline Fosamil is a prescription antibiotic given into a vein to treat certain serious bacterial infections in adults and children. It is used for acute bacterial skin and skin structure infections, including infections caused by some resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA), and for community-acquired bacterial pneumonia, an infection of the lungs acquired outside a hospital.

This medicine kills susceptible bacteria by damaging the protective cell wall they need to survive. It does not treat viral infections such as colds or flu. Using antibiotics only when prescribed and completing the recommended treatment helps reduce the risk of the infection returning and bacteria becoming resistant.

Ceftaroline Fosamil is given as an intravenous infusion (slow drip into a vein), usually by a healthcare professional. The dose, frequency, and length of treatment depend on the type and severity of infection, your age, kidney function, and response to treatment. Because it is given directly into the bloodstream, food does not affect its absorption.

Common side effects may include diarrhoea, nausea, headache, or a reaction where the infusion is given. Consult your doctor right away if you develop severe or bloody diarrhoea, difficulty breathing, swelling of the face or throat, unusual bruising or bleeding, unusual tiredness or pale skin, or new fever or signs of infection.

Before treatment, tell your doctor if you have kidney problems, a history of seizures, bowel problems, or allergies to antibiotics. In particular, tell your doctor if you have ever had an allergic reaction to ceftaroline, another cephalosporin, or a penicillin antibiotic, as allergic reactions can sometimes occur across related antibiotics.

Ceftaroline Fosamil helps treat serious bacterial infections by killing susceptible bacteria and preventing the infection from continuing to spread.

• Effective against certain resistant bacteria: Ceftaroline can treat skin infections caused by susceptible MRSA, providing an option when resistance limits the usefulness of some other antibiotics.
• Helps control serious infection: By killing the bacteria causing the infection, treatment can help the body recover and reduce infection-related symptoms.
• Provides treatment directly into the bloodstream: Intravenous administration provides reliable delivery when treatment with an injectable antibiotic is appropriate.
• Suitable for different age groups: Ceftaroline may be used in adults and children when prescribed at an appropriate dose for the patient's age, weight, kidney function, and infection.

• Follow your doctor’s instructions on the dosage and timing of this medication.
• Typically, it is given every 12 hours for adults and every 8 hours for children for 5-14 days. However, follow your doctor’s advice regarding the dosage and duration.
• Ceftaroline Fosamil will be administered by a doctor or nurse in a healthcare facility.
• Do not self-administer.

Common Side Effects (Usually Mild):

• Nausea or vomiting
• Diarrhoea
• Headache
• Constipation
• Redness, pain, or swelling where the infusion is given

Serious Side Effects (Consult your doctor right away):

• Severe, persistent, watery, or bloody diarrhoea, with or without stomach cramps
• Difficulty breathing or swallowing, hives, or swelling of the face, lips, tongue, or throat
• Severe or widespread skin rash, blistering, or peeling
• New or worsening fever, chills, sore throat, or frequent infections, which may be signs of neutropenia (low levels of certain white blood cells)
• Unusual tiredness, weakness, pale skin, yellowing of the skin or eyes, or dark urine, which may be signs of haemolytic anaemia (breakdown of red blood cells)
• Unusual bruising or bleeding
• Seizures, particularly in people with kidney problems or when the medicine builds up in the body