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Cyclandelate

About Cyclandelate

Cyclandelate is a prescription medicine used to help manage symptoms associated with poor blood circulation, particularly in the arms, legs, fingers, and toes. It works by relaxing and widening blood vessels, which may improve blood flow to affected areas and help relieve circulation-related discomfort.

Take this medicine regularly and exactly as prescribed by your doctor. If the medicine causes stomach upset, your doctor or pharmacist may advise taking it with food or milk. Lifestyle measures such as avoiding smoking, staying physically active as appropriate for your health, and keeping your hands and feet warm may also help support circulation.

Some people may experience side effects such as stomach upset, flushing, headache, dizziness, or a feeling of warmth. These effects are often mild. Consult your doctor if they persist or become troublesome, or if you develop unusual symptoms during treatment.

Do not take this medicine if you are allergic to cyclandelate or any other ingredient in the medicine. Before starting treatment, tell your doctor about your medical conditions, particularly any heart or blood vessel problems or history of bleeding, so they can determine whether this medicine is appropriate for you.

Tell your doctor or pharmacist about all prescription medicines, over-the-counter medicines, and supplements you take before starting this medicine. If you are pregnant, planning to become pregnant, breastfeeding, or an older adult, discuss your treatment with your doctor to make sure it is appropriate for your individual health needs.

Uses of Cyclandelate

Cyclandelate is used in the treatment of peripheral vascular diseases. The detailed uses of Cyclandelate are as follows: • Improves blood circulation in peripheral vascular disease: Cyclandelate helps treat blocked veins in the legs by widening blood vessels. • Manages cerebrovascular insufficiency: Cyclandelate enhances blood flow to the brain, reducing symptoms caused by poor circulation. • Treats arteriosclerosis and Raynaud’s disease: Cyclandelate eases hardening of the arteries and relieves numbness and cold sensations in the hands. • Helps prevent premature labour: Cyclandelate relaxes the smooth muscles of the uterus, reducing the risk of early contractions.

Medicinal Benefits

Cyclandelate may help improve symptoms associated with reduced blood flow by relaxing and widening blood vessels.

  • Improves comfort during movement: Better blood flow to the limbs may help reduce circulation-related pain, cramping, numbness, or discomfort, making everyday movement more comfortable.
  • Helps relieve cold-related symptoms: Improved circulation to the hands and feet may reduce episodes of coldness, discomfort, or colour changes associated with blood vessel narrowing or spasm.

Directions for Use

  • Cyclandelate can be taken with food or as advised by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Cyclandelate as a whole with a glass of water.
  • Do not chew, crush, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cyclandelate

Common Side Effects (Usually mild):

  • Upset stomach, mild nausea, or heartburn
  • Flushing or a sudden feeling of warmth in the face and neck
  • Dizziness or lightheadedness
  • Headache


Serious Side Effects (Consult your doctor right away):

  • Fast, pounding, or irregular heartbeat
  • Severe dizziness or fainting
  • Signs of a severe allergic reaction (such as skin rash, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing)

Drug Warnings

  • Stand up slowly: To avoid dizziness or fainting when getting up from a lying or sitting position, rise gradually.
  • Monitor your heart rate: Keep track of your pulse and report any unusually fast or irregular heartbeats to your doctor.
  • Check for skin changes: Inspect your fingers, toes, and legs daily for any skin colour changes, sores, or signs of poor healing.
  • Inform your surgical team: If you are planning to have any surgery or dental procedures, tell your doctor or dentist that you are taking this medication.
  • Avoid hazardous activities initially: Do not drive or operate machinery until you know how this medicine affects your alertness.

Drug Interactions

  • Blood pressure medications: Combining Cyclandelate with other drugs that lower blood pressure can increase the risk of dizziness and fainting.
  • Other vasodilators: Taking this with other blood-vessel-relaxing drugs may cause excessively low blood pressure.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    unsafe

    Avoid alcohol consumption while taking Cyclandelate as it may increase dizziness and worsen the health condition.

  • Safety Warning

    Pregnancy

    caution

    If you are pregnant or planning pregnancy, inform your doctor before taking Cyclandelate. Your doctor may prescribe this medicine if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    Limited data are available on the effect of Cyclandelate on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Cyclandelate. Your doctor may prescribe this medicine if the benefits outweigh the risks.

  • Safety Warning

    Driving

    unsafe

    Cyclandelate may cause blurry vision and dizziness. Hence, avoid driving or operating heavy machines that require your concentration.

  • Safety Warning

    Liver

    consult your doctor

    There is limited information available on the use of Cyclandelate in patients with liver disease. Please consult your doctor for the best advice.

  • Safety Warning

    Kidney

    consult your doctor

    There is limited information available on the use of Cyclandelate in patients with kidney disease. Please consult your doctor for the best advice.

  • Safety Warning

    Children

    unsafe

    Cyclandelate is not recommended for children as the safety and effectiveness of Cyclandelate have not been established.

Habit Forming

No

Diet & Lifestyle Advise

  • Keep your hands and feet warm: Wear warm gloves and insulated socks, especially during cold weather, to prevent blood vessel spasms.
  • Avoid smoking and nicotine: Smoking causes blood vessels to narrow, which directly counteracts the benefits of your medication.
  • Engage in regular, moderate exercise: Walk regularly as tolerated to help naturally improve your body's overall circulation over time.
  • Manage stress: High stress can trigger sudden blood vessel spasms. Practice relaxation techniques like deep breathing or meditation.
  • Limit caffeine intake: Excessive caffeine can constrict blood vessels and reduce the effectiveness of your treatment.

Special Advise

  • Maintain caution while driving a motor vehicle, operating machinery, or performing other hazardous activities as Cyclandelate may cause dizziness. If you experience dizziness or drowsiness, avoid these activities. Try to rise slowly from a sitting or lying position to avoid falling.
  • Notify your doctor if you experience any skin rash or palpitation (irregular heartbeats) after using Cyclandelate.

Patients Concern

Disease/Condition Glossary

Cerebrovascular insufficiency: It occurs when there is obstruction of one or more blood vessels (arteries) that supply blood to the brain. This obstruction leads to strokes or transient ischemic attacks (TIAs or 'mini-strokes').

Buerger's disease: It commonly occurs in the arms and legs, where blood vessels get swollen, thereby preventing blood flow and causing clots to form. This leads to pain, tissue damage, and the formation of gangrene (death of body tissues).

Raynaud's phenomenon: It occurs due to blocked nerves resulting in discolouration of the fingers and/or the toes after exposure to extreme cold or hot temperatures conditions. Skin discolouration is a sign of a diminished blood supply to the local tissues.

FAQs

Cyclandelate is used to treat Peripheral vascular diseases.

Cyclandelate acts by relaxing and widening blood vessels, thereby increasing the blood flow to the organs, muscles and blocked nerves of the body.

If you forget to take Cyclandelate at any time, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a forgotten dose.

Please do not stop taking Cyclandelate without consulting your doctor, as it may lead to unpleasant effects. Continue taking Cyclandelate for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Cyclandelate.

Yes, but taking it with food or milk is highly recommended as it helps prevent mild stomach upset. Talk to your doctor or pharmacist if stomach discomfort persists.

No, this medicine does not cure the disease, but it helps manage and relieve the symptoms by keeping your blood vessels relaxed and improving blood flow. Talk to your doctor about long-term management.

Mild flushing or a feeling of warmth is a common and usually harmless side effect. However, if it becomes severe, uncomfortable, or is accompanied by a rash, talk to your doctor or pharmacist.

It is best to limit your caffeine intake because caffeine can cause your blood vessels to narrow, which may reduce the positive effects of this medicine. Talk to your doctor for personalised dietary advice.

The safety of this medicine during pregnancy has not been fully established. If you are pregnant or planning to become pregnant, talk to your doctor to weigh the benefits and risks.

Yes, dizziness is a known side effect, especially when you first start taking the medicine or when standing up quickly. Rise slowly from sitting or lying down, and talk to your doctor if the dizziness is severe.

Cyclandelate is an older medicine that has been used to improve blood flow in certain circulation disorders. However, evidence supporting its clinical benefits is limited, and it is no longer routinely used or marketed in several countries, including the US and UK. Its availability and approved uses may vary by country. Your doctor will decide whether this medicine is appropriate for you based on your condition and the treatment options currently available.

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