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Di Iodohydroxyquinoline

About Di Iodohydroxyquinoline

Di Iodohydroxyquinoline is a prescription medication used to treat intestinal amoebiasis, a parasitic infection of the intestines. Its primary medical purpose is to eliminate amoebae (parasites) residing in the bowel, helping to clear both active infections and asymptomatic carrier states. It is specifically formulated to act locally within the intestinal tract to target the source of the infection.

To ensure the infection is completely cleared, you must take this medication regularly and exactly as prescribed by your healthcare provider. It is generally recommended to take this medicine after meals to minimise stomach irritation. Incorporating strict hygiene practices, such as washing hands thoroughly and drinking only safe, purified water, is highly recommended to support your recovery and prevent reinfection.

While taking Di Iodohydroxyquinoline, you may experience mild side effects like nausea, stomach cramps, or a headache. However, if you notice any unusual changes in your vision, or experience numbness or tingling in your hands or feet, you must contact your doctor immediately. These serious symptoms require prompt medical evaluation.

Do not take this if you have a known allergy to iodine or 8-hydroxyquinolines, as this medication contains iodine. Before starting treatment, tell your doctor if you have thyroid disease, liver disease, or problems with the optic nerve (the nerve that carries visual information from your eye to your brain). This medicine may not be suitable if you have severe liver disease or certain conditions affecting the optic nerve. 

Di Iodohydroxyquinoline can interfere with certain medical tests, particularly thyroid function tests, because of its high iodine content. It is important to inform your doctor about all other medications you are taking, and to discuss safety precautions if you are pregnant, breastfeeding, or planning treatment for an elderly family member. Talk to your doctor or pharmacist to determine if this treatment is safe for your specific situation.

Uses of Di Iodohydroxyquinoline

Di Iodohydroxyquinoline is used to treat a wide range of intestinal infections caused by protozoa and certain bacteria. The detailed uses of Di Iodohydroxyquinoline are as follows: • Treatment of intestinal amoebiasis: Di Iodohydroxyquinoline is used to treat amoebic infections in the intestines and reduce related symptoms like diarrhea and abdominal pain. • Non-specific diarrheal conditions: Di Iodohydroxyquinoline helps in managing diarrhea associated with protozoal or bacterial infections. • Prevention of relapse in chronic amoebiasis: Di Iodohydroxyquinoline can help avoid recurrence of intestinal amoebic infections.

Medicinal Benefits

When used as directed as part of your treatment plan, Di Iodohydroxyquinoline may provide the following benefits:

  • Helps clear intestinal amoebiasis: Eliminates the amoebae from your intestines, helping to treat the infection.
  • Relieves digestive symptoms: Helps reduce diarrhoea, stomach cramps, bloating, and abdominal discomfort caused by intestinal amoebiasis.
  • Supports recovery of bowel health: Helps your intestines return to normal function as the infection clears.
  • Helps eliminate asymptomatic infection: Clears amoebae from the intestines of people who carry the infection without symptoms, reducing the risk of ongoing infection.
  • Helps reduce the spread of infection: By removing the parasite from the bowel, it may help reduce transmission to other people when combined with good hygiene practices.

Directions for Use

  • Take Di Iodohydroxyquinoline with food or as advised by your doctor.
  • It is advised to take Di Iodohydroxyquinoline 3 times daily; however, follow your doctor's recommendation regarding the dosage and duration.
  • Swallow Di Iodohydroxyquinoline as a whole with a glass of water.
  • Do not crush, chew, or break Di Iodohydroxyquinoline.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Di Iodohydroxyquinoline

Common Side Effects (Usually mild):

  • Nausea or vomiting
  • Stomach cramps or mild abdominal pain
  • Headache
  • Mild skin itching or rash
     

Serious Side Effects (Consult your doctor right away):

  • Changes in vision, including blurriness or difficulty seeing colors
  • Numbness, tingling, or a burning sensation in your hands or feet
  • Severe muscle weakness or difficulty walking
  • Signs of a severe allergic reaction, such as swelling of the face, tongue, or throat, or severe hives

Medicines Containing this Salt

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Drug Warnings

  • Complete the full course: Continue taking this medicine for the full prescribed duration, even if you start feeling better.
  • Attend scheduled tests: Tell your doctor and laboratory staff that you are taking this medicine, as it may affect the results of certain thyroid function tests.
  • Know when to seek medical advice: Stop taking this medicine and consult your doctor right away if you develop changes in your vision, numbness, tingling, or any other unusual symptoms.
  • Do not share your medicine: Never share this medicine with anyone else, even if they have similar symptoms.
  • Use other medicines with caution: Consult your doctor before taking medicines for diarrhoea or any new medicines while using this treatment.
  • Follow good hygiene practices: Wash your hands regularly and use safe food and drinking water to help prevent reinfection and reduce the spread of intestinal amoebiasis.

Drug Interactions

  • Thyroid medicines: This medicine contains iodine and may affect the results of thyroid function tests. Tell your doctor if you are taking medicines for a thyroid condition or are due to have thyroid tests.
  • Other iodine-containing medicines or supplements: Taking this medicine with other products containing iodine may increase your overall iodine exposure. Tell your doctor about all the medicines, vitamins, herbal products, and supplements you are taking before starting treatment.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Alcohol consumption may increase the risk of side effects and worsen your condition.

  • Safety Warning

    Pregnancy

    caution

    Please consult your doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe Di Iodohydroxyquinoline only if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    Consult your doctor, and there is no substantial research yet on the use of Di Iodohydroxyquinoline in breastfeeding/nursing mothers.

  • Safety Warning

    Driving

    safe if prescribed

    Di Iodohydroxyquinoline may not affect your ability to drive.

  • Safety Warning

    Liver

    caution

    There is limited research on the usage of Di Iodohydroxyquinoline in patients with liver disease. Please consult your physician.

  • Safety Warning

    Kidney

    caution

    There is limited research on the usage of Di Iodohydroxyquinoline in patients with kidney disease. Please consult your physician.

  • Safety Warning

    Children

    caution

    Di Iodohydroxyquinoline should be used with caution in children below 12 years of age. Your doctor will decide the dose of Di Iodohydroxyquinoline based on your child's condition.

Habit Forming

No

Diet & Lifestyle Advise

  • Drink safe water: Drink boiled, filtered, or bottled water to help prevent reinfection with intestinal parasites.
  • Maintain good hand hygiene: Wash your hands thoroughly with soap and water after using the toilet, changing nappies, and before preparing or eating food.
  • Choose safe foods: Avoid raw or undercooked foods, unpeeled fruits and vegetables, and food from unhygienic sources until you have recovered.
  • Stay hydrated: Drink plenty of safe fluids, such as water or oral rehydration solution, especially if you have diarrhoea.
  • Prevent the spread of infection: Avoid preparing food for others while you have diarrhoea, and follow good household hygiene practices to help reduce the spread of infection.

Patients Concern

Disease/Condition Glossary

Amoebic dysentery: It is an intestinal (bowel) illness caused by a parasite (amoeba) known as Entamoeba histolytica spread through human faeces (poop). Usually, there are no symptoms, but sometimes it causes diarrhoea (loose stool/poop), nausea (a feeling of sickness in the stomach) and weight loss.

Balantidiasis: Balantidiasis is the inflammation of the large intestine (colon) caused by Balantidium coli. Symptoms include chronic diarrhoea, nausea, abdominal pain and weight loss.

FAQs

Di Iodohydroxyquinoline belongs to a group of medications called antiprotozoal agents used to treat Amoebiasis, also known as amebic dysentery.

Di Iodohydroxyquinoline is an antiprotozoal agent used to treat Amoebiasis and Balantidiasis. It acts by identifying and killing the growing parasites in the intestines, which cause dysentery.

Di Iodohydroxyquinoline is not recommended for long-term use. This medicine is usually given for 20 days.

Di Iodohydroxyquinoline contains 'iodine' and may interfere with some thyroid tests if this medicine is taken in patients with thyroid problems.

Do not stop taking this medicine even if you feel better, as it may cause a recurrence of symptoms. So, completing the course of therapy as prescribed by your doctor is always recommended.

Di Iodohydroxyquinoline should be taken with food to prevent gastric irritation and side effects such as diarrhoea, nausea, and vomiting.

Before taking Di Iodohydroxyquinoline, let your doctor know if you have any thyroid problems, kidney or liver problems, if you are pregnant or breast-feeding, and if you are taking any prescription or non-prescription medicines, dietary supplements, or herbal products.

No, Di Iodohydroxyquinoline should not be used for viral infections like cold and flu, as it is used for the treatment of amoebiasis, balantidiasis, and fungal and bacterial infections.

Do not take Di Iodohydroxyquinoline if you are allergic to any of its ingredients. It should be used with caution in patients with thyroid problems and neurological disorders associated with the brain and spinal cord.

The side effects of Di Iodohydroxyquinoline include dizziness, diarrhoea, vomiting, headache, abdominal cramps, skin itchiness, fever, chills, and an enlarged thyroid. Consult the doctor if any of these side effects persist or worsen.

Di Iodohydroxyquinoline should be taken during pregnancy or breastfeeding only if the doctor has prescribed it. The doctor will prescribe this medication only if the benefits outweigh the risks.

If you have missed the dose, take it as soon as you remember and if it's already time for the next dose, skip the missed dose and take the scheduled dose. Do not double the dose.

It is highly recommended to take Di Iodohydroxyquinoline after meals. This helps reduce the likelihood of experiencing common side effects like nausea or stomach irritation. Talk to your doctor or pharmacist for personalised advice.

You must stop taking the medication immediately and contact your doctor. Vision changes can be a sign of a serious reaction affecting the optic nerve. Talk to your doctor right away.

No, Di Iodohydroxyquinoline is specifically designed to treat parasitic infections like amoebiasis. It will not work against viral or bacterial infections, such as the common stomach flu. Talk to your doctor for an accurate diagnosis.

The safety of this medication during pregnancy has not been fully established. It should only be used if the potential benefit justifies the risk. Talk to your doctor before taking this medicine if you are pregnant.

Yes, because Di Iodohydroxyquinoline contains a significant amount of iodine, it can interfere with the results of thyroid function tests for several weeks after you stop taking it. Talk to your doctor before scheduling any blood tests.

Signs of iodine sensitivity or toxicity include skin rashes, hives, fever, or swelling of the salivary glands. If you experience these symptoms, stop taking the medicine and talk to your doctor.

The duration of treatment depends entirely on your specific diagnosis and your doctor's instructions. You must complete the entire course as prescribed, even if you feel completely better. Talk to your doctor if you have questions about your schedule.

No, you should not stop taking the medication early. Stopping treatment too soon can allow the remaining parasites to survive and cause the infection to return. Talk to your doctor before making any changes to your treatment.

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