Evogliptin+metformin
About Evogliptin+metformin
Evogliptin+metformin is an oral prescription medication used to manage blood sugar levels in adults with type 2 diabetes. It is prescribed when diet and exercise alone do not provide enough control over blood glucose levels. By combining two distinct blood sugar-lowering medicines, it helps keep your diabetes under control.
To get the best results, you must take Evogliptin+metformin regularly and consistently as prescribed by your doctor. This oral tablet is typically taken with meals to minimise the chance of experiencing an upset stomach. Combining this medication with a balanced diet and regular physical activity will significantly improve your blood sugar management.
While taking Evogliptin+metformin, some people may experience mild side effects like nausea, diarrhoea, or a runny nose. However, you must seek immediate medical attention and consult your doctor if you experience rare but serious symptoms, such as severe stomach pain or signs of an allergic reaction.
Before starting this medicine, talk to your doctor if you have a history of liver damage, heart failure, or kidney problems. Do not take this if you have severe kidney disease, diabetic ketoacidosis, or a known allergy to any of its components.
This medicine can interact with certain other drugs, smoking, and alcohol, which can increase the risk of a dangerous buildup of acid in your blood. If you are pregnant, planning to become pregnant, breastfeeding, or are an elderly individual, you should consult your doctor before starting this treatment.
Uses of Evogliptin+metformin
Medicinal Benefits
Managing type 2 diabetes effectively with Evogliptin+metformin offers several important health benefits:
- Steady blood sugar control: By targeting different pathways in the body, it helps prevent sharp rises in blood sugar after meals and maintains stable glucose levels throughout the day.
- Prevention of long-term complications: Keeping your blood sugar in check reduces your risk of developing severe diabetes-related problems, such as kidney damage, nerve damage, vision loss, and cardiovascular issues.
- Convenience of combination therapy: Taking two active therapies in a single tablet makes it easier to follow your treatment plan compared to taking multiple separate pills.
Directions for Use
- Evogliptin+metformin can be taken with or without food, as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow the whole Evogliptin+metformin with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Evogliptin+metformin
Common Side Effects (Usually mild):
- Nausea or upset stomach
- Diarrhea or loose stools
- Headache
- Runny nose, sore throat, or cold-like symptoms
Serious Side Effects (Consult a doctor right away):
- Severe, constant pain in the abdomen that may spread to your back (a sign of pancreas inflammation)
- Extreme tiredness, rapid or deep breathing, muscle pain, shivering, or feeling unusually cold (signs of a rare but serious buildup of acid in the blood)
- Signs of a severe allergic reaction, such as swelling of the face, lips, tongue, or throat, or difficulty breathing
- Severe joint pain
Medicines Containing this Salt
View AllDrug Warnings
- Monitor kidney function: Your doctor should check how well your kidneys are working before you start taking this medicine and at least once a year during treatment.
- Watch out for low blood sugar: While Evogliptin+metformin alone rarely causes low blood sugar, it can happen when combined with other diabetes medicines. Keep a fast-acting sugar source, like fruit juice or glucose tablets, with you.
- Avoid heavy alcohol use: Drinking excessive alcohol while taking this medicine can increase the risk of a dangerous buildup of acid in your blood.
- Pause before certain medical tests: Tell your doctor you are taking Evogliptin+metformin if you need to have an X-ray or scan that involves injecting a contrast dye, as you may need to stop taking the medicine temporarily.
- Stop before surgery: If you are planning to have a surgical procedure under anaesthesia, discuss with your doctor when to stop taking this medicine and when to restart it.
Drug Interactions
- Water pills (diuretics) and steroids: These medicines can increase blood sugar levels, potentially reducing the effectiveness of Evogliptin+metformin.
- Other blood sugar lowering medicines: Combining this medicine with insulin or certain oral diabetes drugs may increase the risk of low blood sugar.
- Certain heart and blood pressure medicines: Some blood pressure drugs may hide the warning signs of low blood sugar, such as a fast heart rate.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.
Pregnancy
cautionLimited information is available on the use of Evogliptin+metformin in pregnant women. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Breast Feeding
cautionLimited information on the use of Evogliptin+metformin in breastfeeding mothers is available. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Driving
cautionIf your blood sugar is too low or too high, your driving ability may be affected. Do not drive if these symptoms appear.
Liver
cautionThere is limited information available on the use of Evogliptin+metformin in patients with liver disease. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Please consult your doctor.
Kidney
cautionLimited information is available on using Evogliptin+metformin in patients with kidney disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Children
unsafeEvogliptin+metformin is not recommended for people younger than 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Eat a balanced diet: Focus on whole grains, lean proteins, and plenty of non-starchy vegetables. Limit foods high in refined sugars and simple carbohydrates to avoid blood sugar spikes.
- Stay active: Aim for at least 150 minutes of moderate physical activity, like brisk walking or cycling, per week. Regular exercise helps your body use insulin more efficiently.
- Monitor your blood sugar: Keep a regular log of your blood glucose levels as advised by your doctor to track how your treatment is working.
- Do not skip meals: Eating your meals at consistent times helps prevent your blood sugar from dropping too low, especially when taking diabetes medications.
- Stay hydrated: Drink plenty of water throughout the day to support your kidney function and help your body process the medication safely.
Special Advise
Keep taking Evogliptin+metformin even if your blood sugar levels are controlled.
Take short, frequent meals, and avoid prolonged fasting when taking Evogliptin+metformin. Beware of hypoglycaemia symptoms, including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.
Patients Concern
Disease/Condition Glossary
Type 2 diabetes mellitus: Type 2 diabetes mellitus is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilization of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin; in later stages, your body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite and dry mouth. If not properly treated, this condition may worsen over time and cause toxic effects.
FAQs
Evogliptin+metformin is used as an adjunct to diet and exercise to improve glycaemic control in adult patients with type 2 diabetes mellitus. This medication improves glycaemic control in diabetic patients who do not react well to metformin alone. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than usual.
Evogliptin+metformin contains Metformin and Evogliptin. Metformin works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin. Evogliptin works by increasing insulin release from the pancreas and decreasing the hormones that raise blood sugar levels. Altogether Evogliptin+metformin reduces sugar levels in the body.
If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. Always carry glucose tablets or sugar candies with you.
Do not discontinue taking Evogliptin+metformin without consulting your doctor. Take Evogliptin+metformin for as long as it has been advised by the doctor. If you experience any difficulty while taking Evogliptin+metformin, consult a doctor.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.
The side effects of Evogliptin+metformin include nausea, vomiting, headache, stomach pain, diarrhoea, and indigestion. If these side effects persist or worsen, please consult your doctor.
Medicines used to secrete insulin or insulin injections raise the risk of hypoglycemia (low blood sugar levels) when taken with metformin. Therefore, inform your doctor if you are on insulin injections before starting Evogliptin+metformin.
There are no human studies conducted to see the effects of Evogliptin+metformin on fertility. However, studies on animals do not show the harmful effects of high doses of evogliptin and metformin on the fertility in both the genders in rats and mice. If you have any concerns regarding this, please discuss with your doctor.
There is no information on role of Evogliptin+metformin in causing cancer as no human studies have been performed. However, animal studies results do not show cancer.
It is generally not recommended to take Evogliptin+metformin during pregnancy. Your doctor will likely switch you to a different treatment to manage your blood sugar levels while pregnant. Talk to your doctor if you are pregnant or planning to become pregnant.
No, Evogliptin+metformin is typically weight-neutral and is not associated with significant weight gain. In some cases, it may even support modest weight management when combined with a healthy diet and regular physical activity. Talk to your doctor if you have concerns about your weight.
You should avoid heavy or excessive alcohol intake while taking Evogliptin+metformin. Alcohol increases the risk of a rare but very serious condition called lactic acidosis, which is a dangerous buildup of acid in the blood. Talk to your doctor or pharmacist about safe alcohol consumption limits.
Mild diarrhea and stomach upset are common when first starting Evogliptin+metformin, and they usually improve over a few weeks. Taking your medicine with meals can help reduce these symptoms. However, if your diarrhea is severe, persistent, or accompanied by dehydration, talk to your doctor.
You may need to stop taking Evogliptin+metformin temporarily before undergoing surgery involving general anaesthesia. Your medical team will instruct you on when to stop the medication and when it is safe to restart. Talk to your doctor before any scheduled surgical procedure.
Although Evogliptin+metformin alone has a low risk of causing hypoglycemia (low blood sugar), the risk increases if you take it with insulin or other diabetes medicines, skip or delay meals, drink excessive alcohol, or perform intense physical activity. Symptoms may include sweating, shakiness, dizziness, hunger, or confusion. If you think your blood sugar is low, consume glucose tablets, sugar candies, or another fast-acting source of sugar immediately, and monitor your blood sugar if possible. Talk to your doctor about how to recognise and manage hypoglycemia.
The best time to take Evogliptin+metformin is usually with your morning or evening meal, as directed by your doctor. Taking it with a meal helps protect your stomach from irritation. To get the best results, try to take it at the same time every day, and talk to your doctor if you need to adjust your schedule.
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