Flupentixol
About Flupentixol
Flupentixol is a prescription medication used to manage symptoms of long-term mental health conditions, such as schizophrenia and chronic psychoses. It may also be prescribed in lower doses to treat depression and anxiety. By targeting certain natural chemicals in the brain, this medicine helps restore a healthy balance, improving thoughts, feelings, and behaviour.
For this medicine to work effectively, it must be taken regularly and consistently exactly as prescribed by your doctor. You can take Flupentixol with or without food, but taking it at the same time each day helps maintain steady levels in your body. Making positive lifestyle changes, such as managing stress and establishing a regular sleep routine, can also support your treatment outcomes.
While taking Flupentixol, you may experience mild side effects like drowsiness or a dry mouth. However, you must contact your doctor immediately if you notice more serious symptoms, such as severe muscle stiffness, high fever, or unusual shaking that you cannot control.
Talk to your doctor before starting this medicine if you have any pre-existing health conditions. Do not take this medicine if you have Parkinson's disease, cardiovascular collapse or circulatory shock, or if you are experiencing reduced alertness due to alcohol, sedatives, or other central nervous system depressants.
This medicine can interact with alcohol, which can significantly increase drowsiness and dizziness. If you smoke, let your doctor know, as smoking can affect how quickly your body processes this medicine. If you are pregnant, planning to become pregnant, breastfeeding, an older adult, or considering treatment for a child or adolescent, consult your healthcare provider before taking Flupentixol. Older adults are often started on lower doses because they may be more sensitive to side effects. In some people, your doctor may also recommend a long-acting injectable form of flupentixol for long-term symptom control instead of daily tablets.
Uses of Flupentixol
Medicinal Benefits
Flupentixol helps improve mental well-being by balancing certain chemical messengers in the brain. Regular use, as prescribed, helps control symptoms, improve daily functioning, and reduce the risk of symptom relapse.
- Supports long-term control of schizophrenia: Regular treatment helps reduce hallucinations, delusions, and disorganised thinking. Although some improvement may be noticed within a few weeks, full stabilisation of symptoms often takes several weeks to months.
- Improves mood and reduces anxiety: When prescribed in lower doses, Flupentixol may help improve mood, reduce anxiety, and relieve persistent feelings of tension. Some people may notice improvement in these symptoms earlier than in psychotic symptoms.
- Promotes better daily functioning: By helping control symptoms over time, the medicine may make it easier to participate in work, social activities, and daily routines while reducing the risk of relapse.
Directions for Use
- Flupentixol can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow Flupentixol as a whole with a glass of water.
- Do not chew, crush, or break it.
Storage
Side Effects of Flupentixol
Common Side Effects (Usually mild)
- Sleepiness or drowsiness
- Dry mouth
- Mild shaking or trembling in the hands
- Constipation or mild stomach upset
Serious Side Effects (Consult your doctor right away)
- Severe muscle stiffness, high fever, sweating, and rapid breathing
- Uncontrolled movements of your tongue, face, mouth, or jaw (tardive dyskinesia), particularly after long-term use
- Yellowing of your skin or the whites of your eyes (signs of liver damage)
- Signs of a serious allergic reaction, such as swelling of the face, tongue, or throat, or severe hives
Medicines Containing this Salt
View AllDrug Warnings
- Inspect the Tablets Before Use: Do not take the tablets if they appear damaged, broken, discoloured, or expired.
- Do Not Stop Treatment Suddenly: Do not discontinue Flupentixol without consulting your doctor, as abrupt withdrawal may cause your symptoms to return or lead to withdrawal effects.
- Use Caution During Activities: Avoid driving, cycling, or operating machinery until you know how Flupentixol affects your alertness and coordination.
- Inform Healthcare Providers: Tell your doctor, dentist, or surgeon that you are taking Flupentixol before any medical, dental, or surgical procedure.
Drug Interactions
Inform your doctor if you are taking any of the following medicines, as they may interact with Flupentixol:
- Medicines That Cause Drowsiness: Sleeping tablets, opioid pain medicines, sedating antihistamines, and similar medicines may increase drowsiness and dizziness.
- Blood Pressure Medicines: These may increase the risk of low blood pressure and dizziness when used with Flupentixol.
- Other Medicines That Affect the Brain: Antidepressants, antipsychotics, and other medicines acting on the central nervous system may increase side effects or alter treatment response.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Flupentixol as it may cause increased drowsiness and lower your blood pressure.
Pregnancy
unsafeAvoid using Flupentixol during pregnancy because the safety of Flupentixol has not established. Please consult your doctor before taking Flupentixol.
Breast Feeding
unsafeFlupentixol can pass into the breastmilk, so it is not safe to breastfeed while taking Flupentixol. Consult your doctor before taking Flupentixol.
Driving
unsafeFlupentixol causes drowsiness and sleepiness. Do not drive or operate machinery without consulting your doctor.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
unsafeFlupentixol is not recommended for children.
Habit Forming
Diet & Lifestyle Advise
- Stay Well-Hydrated and Eat Fibre-Rich Foods: Drink plenty of water and include fibre-rich foods in your diet to help reduce constipation and relieve dry mouth.
- Stand Up Slowly: Rise gradually from a sitting or lying position to reduce the risk of dizziness or lightheadedness.
- Avoid Overheating: Stay cool and drink adequate fluids, especially in hot weather, as Flupentixol may reduce your ability to sweat.
- Limit Caffeine if Needed: Reduce caffeine intake if you experience restlessness, nervousness, or difficulty sleeping while taking this medicine.
Special Advise
While taking Flupentixol you may become more sensitive to extreme temperature conditions (like too hot or too cold temperature), so it is advisable to avoid getting too cold or too hot or becoming dehydrated especially during summer. Drink plenty of fluid and water to cope with this condition.
Patients Concern
Disease/Condition Glossary
Schizophrenia: It is a condition in which the person may see, hear, or feel things that are not there, believe things that are not true, feel unusually suspicious or confusing. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganized thinking, loss of interest, lack of emotions, etc. Although schizophrenia is not as common as other major mental diseases, it can be the most chronic and deactivating.
Depression: It is a common mental disorder and characterized by constant sadness and a lack of interest or joy in previously rewarding or enjoyable activities. It can also disturb sleep and appetite and poor concentration and tiredness are common.
FAQs
Flupentixol is used to treat schizophrenia and other mental disorder that affects the way you feel, think or behave.
Flupentixol works by balancing the chemical messengers called neurotransmitter and blocking the effect of dopamine located in the brain, thereby helps in improving mood, behaviour, and thoughts.
Flupentixol may cause affect the blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Flupentixol. Diabetes patients should consult a doctor before taking Flupentixol.
Flupentixol may cause side effects like sleepiness, dryness in the mouth, orthostatic hypotension (sudden lowering of blood pressure on standing), weight gain, abnormality of voluntary movements (expression of thought through action), urinary retention (completely emptying the bladder), muscle stiffness, constipation, and tremor. If any of the side effects are persistent, reach out to your doctor.
Flupentixol is an antipsychotic medicine. It contains Flupentixol used to treat schizophrenia and other mental disorder that affects the way you feel, think or behave.
No, you should not stop taking this medicine suddenly, even if you feel completely better. Stopping it abruptly can cause your symptoms to return or lead to withdrawal effects. Your doctor will advise you on how to slowly reduce your dose when it is safe to do so. Talk to your doctor before making any changes.
Some people may experience changes in appetite or weight while taking this medicine. Eating a balanced diet and staying active can help manage these effects. If you are concerned about weight changes, talk to your doctor or pharmacist.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol can increase side effects like extreme drowsiness, dizziness, and poor coordination, which can be dangerous. Talk to your doctor if you have questions about alcohol use.
You may begin to notice some improvements within a few weeks, but it can take several weeks or even months of consistent use to feel the full therapeutic benefits. Do not stop taking the medicine if you do not see immediate results. Talk to your doctor if you have concerns about your progress.
Drowsiness is a common side effect, especially when you first start taking this medicine. Avoid driving or operating machinery if you feel sleepy. This effect often improves over time as your body adjusts. If the drowsiness is severe or does not go away, talk to your doctor.
You should only take this medicine during pregnancy or breastfeeding if your doctor determines that the benefits outweigh the potential risks to the baby. If you are planning a pregnancy or discover you are pregnant, talk to your doctor immediately.
Dry mouth is a common issue that can be managed by sipping water regularly, chewing sugar-free gum, or sucking on sugar-free hard candies. If dry mouth persists and becomes highly uncomfortable, talk to your doctor or dentist for further advice.
Yes, this medicine can sometimes cause a temporary drop in blood pressure, especially when you stand up quickly, which may make you feel dizzy. Standing up slowly can help prevent this. If you experience persistent dizziness or fainting, talk to your doctor.

