Micafungin
About Micafungin
Micafungin is an antifungal medicine used to treat serious infections caused by certain fungi, especially Candida. It may be used for invasive candidiasis, where Candida infects the blood or other parts of the body, and oesophageal candidiasis, which affects the food pipe. It can also help prevent Candida infections in certain people undergoing a stem cell transplant.
This medicine damages the protective wall that fungal cells need to survive. It is mainly used for Candida infections. Micafungin may also be used in certain cases of invasive aspergillosis, a serious infection caused by Aspergillus mould, when your doctor considers it appropriate. Approved uses can vary between countries, so your doctor will decide whether this medicine is suitable for your infection.
Micafungin is given slowly into a vein by a healthcare professional, usually once daily. Treatment may be given in a hospital, clinic, or another supervised healthcare setting. Because it is given directly into the bloodstream, food does not affect how the medicine is absorbed.
Common side effects may include nausea, vomiting, diarrhoea, headache, or reactions where the medicine enters the vein. Consult your doctor right away if you develop difficulty breathing, swelling of the face or throat, a severe skin reaction, unusual bleeding, or yellowing of the skin or eyes.
Before treatment, tell your doctor if you have liver or kidney problems, blood disorders, or have previously had an allergic reaction to micafungin or another echinocandin antifungal, such as caspofungin or anidulafungin. Tell your doctor about all medicines you take, including prescription medicines, over-the-counter medicines, vitamins, and herbal products. Also tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, are an older adult, or if the medicine is intended for a child.
Uses of Micafungin
Medicinal Benefits
Micafungin helps treat or prevent serious fungal infections in people who need an antifungal medicine given directly into the bloodstream.
- Controls serious fungal infections: This medicine damages fungal cells, helping clear infections that may affect the blood, food pipe, or other parts of the body.
- Helps relieve infection-related symptoms: As the infection improves, symptoms such as fever, chills, or painful swallowing may also improve.
- Protects people at high risk: It can help prevent Candida infections in certain people whose immune defences are weakened, such as those undergoing a stem cell transplant.
- Provides an intravenous treatment option: Because it is given directly into a vein, it can be used when intravenous antifungal treatment is needed.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication.
- Micafungin is administered by the doctor or healthcare professional.
- Do not self-administer.
Storage
Side Effects of Micafungin
Common Side Effects (Usually Mild)
- Nausea or vomiting
- Diarrhoea or stomach discomfort
- Headache
- Fever
- Changes in some blood test results
- Pain, redness, or swelling where the infusion is given
Serious Side Effects (Consult your doctor right away)
- Difficulty breathing, wheezing, or swelling of the face, lips, tongue, or throat
- Severe or widespread rash, blistering, or peeling of the skin
- Yellowing of the skin or eyes, dark urine, or unusual tiredness
- Unusual bruising or bleeding
- Severe weakness, pale skin, dark urine, or shortness of breath, which may be signs of red blood cell breakdown
- Severe dizziness, fainting, or other signs of a serious infusion or allergic reaction
Medicines Containing this Salt
View AllDrug Warnings
- Report allergy symptoms: Tell your healthcare team immediately if you develop difficulty breathing, swelling, severe dizziness, or a widespread rash during or after the infusion.
- Mention previous antifungal allergies: Tell your doctor if you have had an allergic reaction to micafungin or another echinocandin antifungal, such as caspofungin or anidulafungin, as a reaction to related medicines may be possible.
- Keep up with blood tests: Your doctor may check your liver function, kidney function, blood cell counts, or other blood tests during treatment.
- Report liver symptoms: Consult your doctor right away if you develop yellowing of the skin or eyes, dark urine, severe tiredness, or other symptoms that could suggest a liver problem.
- Watch the infusion site: Tell your healthcare professional if you develop pain, redness, burning, or swelling where the medicine enters your vein.
- Complete your treatment: Continue treatment for as long as your doctor recommends, even if your symptoms improve before the course is finished.
- Share your medicine list: Tell your healthcare team about all medicines, vitamins, supplements, and herbal products you use so they can check for possible interactions.
Drug Interactions
- Sirolimus: Micafungin can increase the amount of sirolimus in the blood, which may increase its side effects. Your doctor may monitor you closely and adjust treatment if needed.
- Nifedipine: Micafungin can increase exposure to nifedipine, which may increase side effects such as dizziness, flushing, or low blood pressure. Your doctor may adjust the nifedipine dose if needed.
- Itraconazole: Micafungin can increase the amount of itraconazole in the body. This may increase the risk of itraconazole-related side effects, so your doctor may monitor you and adjust treatment when necessary.
- Other antifungal medicines: More than one antifungal may sometimes be used for a serious infection, but combinations should be managed by your doctor to make sure they are appropriate and safe.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known whether Micafungin interacts with alcohol. Please consult your doctor.
Pregnancy
cautionPlease consult your doctor if you are pregnant. It should be used during pregnancy only if clearly needed.
Breast Feeding
cautionPlease consult the doctor if you are breastfeeding. Your doctor will decide if Micafungin can be administered to lactating mothers.
Driving
cautionMicafungin is unlikely to have an effect on driving. However, some people may experience dizziness. Drive or operate machinery only if you are alert.
Liver
cautionIf you have a history of liver problems, inform the doctor before receiving Micafungin.
Kidney
cautionIf you have a history of kidney problems, inform the doctor before receiving Micafungin.
Children
cautionPlease consult the doctor if you have any concerns regarding the usage of Micafungin in children.
Habit Forming
Diet & Lifestyle Advise
- Eat a balanced diet: Choose nutritious foods that provide enough protein, vitamins, and minerals to support your general health during treatment.
- Stay hydrated: Drink enough fluids unless your healthcare team has advised you to limit them.
- Follow food-safety advice: If your immune system is weakened, follow your healthcare team's advice about safely preparing and storing food to reduce your risk of other infections.
- Maintain good oral care: If you have soreness or difficulty swallowing due to oesophageal candidiasis, gentle mouth care may help keep your mouth comfortable.
- Keep follow-up appointments: Attend scheduled blood tests and medical reviews so your healthcare team can check your response to treatment and identify possible side effects.
Special Advise
- The doctor may advise liver function tests during treatment.
Patients Concern
Disease/Condition Glossary
Fungal infection: Fungal infection, also known as mycosis, is a disease caused by fungus. The fungi may invade the tissues and cause a disease confined to the skin, spread into the tissue, organs and bones, or affect the whole body. Symptoms include fatigue, headache, muscle or joint pain, itchy or scaly skin, weight loss, chest pain, and night sweats.
FAQs
Micafungin is used to treat Fungal infections.
Micafungin works by causing defects in the fungal cell wall, making them unable to live and grow. Thereby, it helps treat fungal infections.
Micafungin may cause abnormal blood tests (decreased white/red blood cells and platelets), abnormal liver function tests (increased alkaline phosphatase, increased alanine aminotransferase, increased aspartate aminotransferase) or abnormal kidney function tests (increased urea in the blood, increased blood creatinine). If you are undergoing any tests, inform the doctor that you are on treatment with Micafungin.
The efficacy of Micafungin against infections caused by fungi other than Candida has not been established. Consult the doctor if you have any concerns.
This medicine is mainly used for serious Candida infections, including invasive candidiasis and oesophageal candidiasis. It may also be used to prevent Candida infections in certain high-risk patients. In some settings, doctors may consider micafungin for invasive aspergillosis. Approved uses vary between countries.
This medicine is given slowly into a vein, usually over about 1 hour. It is prepared and administered by a trained healthcare professional.
The length of treatment depends on the type and severity of your fungal infection, your response to treatment, and your test results. Some infections require treatment for several weeks. Your doctor will tell you when it is safe to stop.
Yes, this medicine can sometimes affect the liver. Your doctor may check your liver function with blood tests during treatment. Consult your doctor right away if you notice yellowing of your skin or eyes, dark urine, or unusual tiredness.
Tell your doctor before treatment if you have had an allergic reaction to either medicine. They belong to the same group of antifungal medicines as micafungin, so your doctor will carefully assess whether this medicine is suitable for you.
Micafungin can increase the amount of itraconazole in your body, which may increase the risk of itraconazole-related side effects. Your doctor may monitor you more closely or adjust treatment if needed.
Blood tests can help your doctor check how your liver and kidneys are working, monitor your blood cells, and assess how you are responding to treatment.
There is no well-established direct interaction between micafungin and alcohol. However, because this medicine can affect the liver, ask your doctor whether alcohol is appropriate for you during treatment, particularly if you have liver problems or take other medicines that affect the liver.
Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Your doctor will consider the possible benefits and risks before deciding whether this medicine is appropriate for you.
Tell your nurse or healthcare professional right away. Pain, redness, burning, or swelling around the infusion site should be checked to make sure the intravenous line and surrounding area are safe.
