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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Brutica 100 Capsule 30's is used to treat Mantle cell lymphoma (MCL), chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL). It contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that transmit signals to cells, telling them to grow and divide. Acalabrutinib inhibits these signals to cancer cells. Cells die when their signals are disrupted. This could help to slow the progression of the cancer.

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Side effects of Brutica 100 Capsule
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Avoid taking raw fruits, nuts and vegetables.
  • Do not share your personal things with others like toothbrushes.
  • Clean the wounds and cuts using soap and water.
  • Wash your hands thoroughly and frequently and maintain hygiene.
  • Get a good quality of sleep.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Brutica 100 Capsule:
The combined use of Brutica 100 Capsule and Diclofenac Diethylamine can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Brutica 100 Capsule and Diclofenac Diethylamine can lead to an interaction, but it can be taken if a doctor advises. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting blood, severe headache, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Brutica 100 Capsule:
Co-administration of Brutica 100 Capsule with Lansoprazole may reduce the effectiveness of Brutica 100 Capsule.

How to manage the interaction:
Although there is a possible interaction between Lansoprazole and Brutica 100 Capsule, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Brutica 100 Capsule:
Taking Verapamil with Brutica 100 Capsule can significantly increase the blood levels of Brutica 100 Capsule.

How to manage the interaction:
Although taking verapamil and Brutica 100 Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, headache, shortness of breath, chest pain or tightness, rapid heartbeat, fever, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Brutica 100 Capsule:
Co-administration of Dexlansoprazole may interfere with the absorption of Brutica 100 Capsule capsules and reduce its effectiveness.

How to manage the interaction:
Consult your doctor if you are taking dexlansoprazole and Brutica 100 Capsule. The doctor may prescribe alternatives that do not interact with Brutica 100 Capsule or interact to a lesser extent.
How does the drug interact with Brutica 100 Capsule:
Coadministration of Aprepitant can significantly increase the blood levels of Brutica 100 Capsule.

How to manage the interaction:
Although there is an interaction between Aprepitant and Brutica 100 Capsule, it can be taken if prescribed by a doctor. A doctor should be consulted if you experience any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in the phlegm, red or irritated skin, body sores, and discomfort when urinating. Without consulting a doctor, never stop taking medicines.
How does the drug interact with Brutica 100 Capsule:
Taking Dabigatran etexilate with Brutica 100 Capsule can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Brutica 100 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Brutica 100 Capsule:
Co-administration of Brutica 100 Capsule and Diltiazem can significantly increase the blood levels of Brutica 100 Capsule.

How to manage the interaction:
Although taking Diltiazem and Brutica 100 Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like feeling sick, stomach pain, or unusual bleeding, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Brutica 100 Capsule:
When Brutica 100 Capsule is taken with Erythromycin, the amount of Brutica 100 Capsule in the blood can increase.

How to manage the interaction:
Taking Erythromycin with Brutica 100 Capsule together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs and symptoms - feeling sick, diarrhea, stomach pain, bleeding, feeling weak, dizzy, faint, fever, sore throat, muscle pain, trouble breathing, or pain while urinating - make sure to call your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Brutica 100 Capsule:
Taking Brutica 100 Capsule with posaconazole can considerably raise Brutica 100 Capsule levels in the blood. This may increase the side effects such as infections, abnormal heart rhythm, and bleeding.

How to manage the interaction:
Although using posaconazole and Brutica 100 Capsule together can result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination.
How does the drug interact with Brutica 100 Capsule:
Using Brutica 100 Capsule together with dalteparin may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Dalteparin with Brutica 100 Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs, it's important to contact your doctor right away: bleeding, serious bleeding, problems, bruising, feeling dizzy or lightheaded, having red or black, sticky stools, a very bad headache, feeling weak, or experiencing bleeding or vomiting. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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