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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Croner 5mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Drug-Drug Interactions

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NorethisteroneFosphenytoin
Severe

Drug-Drug Interactions

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How does the drug interact with Croner 5mg Tablet:
Coadministration of Croner 5mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Croner 5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneFosphenytoin
Severe
How does the drug interact with Croner 5mg Tablet:
Coadministration of Croner 5mg Tablet with Fosphenytoin can reduces the blood levels and effects of Croner 5mg Tablet .

How to manage the interaction:
Taking Croner 5mg Tablet with Fosphenytoin together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms of abnormal bleeding while using birth control, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Croner 5mg Tablet:
Eslicarbazepine may reduce the effects of Croner 5mg Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Croner 5mg Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Croner 5mg Tablet:
Taking Croner 5mg Tablet with rifampicin can decrease the blood levels of Croner 5mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Croner 5mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Croner 5mg Tablet:
Coadministration of Croner 5mg Tablet with Oxcarbazepine can reduce the blood levels and effects of norethindrone. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking oxcarbazepine and Croner 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately Do not discontinue any medications without consulting a doctor.
NorethisteroneAmprenavir
Severe
How does the drug interact with Croner 5mg Tablet:
Coadministration of Amprenavir and Croner 5mg Tablet together may reduce amprenavir effects.

How to manage the interaction:
Combining Amprenavir with Croner 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Croner 5mg Tablet:
Coadministration of Croner 5mg Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Croner 5mg Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Croner 5mg Tablet:
Using Etretinate and Croner 5mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Croner 5mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
NorethisteroneFosamprenavir
Severe
How does the drug interact with Croner 5mg Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking Croner 5mg Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Croner 5mg Tablet:
Taking griseofulvin with Croner 5mg Tablet may reduce blood levels and the effects of Croner 5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Croner 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Croner 5mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Croner 5mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Croner 5mg Tablet dose.

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