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Dabigo 150 mg Capsule is used to prevent blood clot formation. It contains Dabigatran, which works by inhibiting the production of clotting factors and makes your blood flow easily through your veins. It may cause side effects such as bleeding, anaemia (low number of red blood cells), nausea, stomach pain, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Dabigo 150 mg Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Avoid other medicines that increase the risk of bleeding.
  • Use an electric razor and a soft-bristled toothbrush.
  • Monitor for signs of bleeding like bleeding gums, unusual bruising, blood in stool, nosebleeds, or heavy menstrual bleeding.
  • If you experience severe bleeding, apply direct pressure on the wound and consult a doctor promptly.
  • If the risk of bleeding is high, discuss with your doctor about possibility of switching to different medicine with a lower bleeding risk.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

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Drug-Drug Interactions

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Drug-Drug Interactions: Dabigo 150 mg Capsule may interact with medicines to reduce blood clotting (warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban), medicines to treat abnormal heartbeats (amiodarone, dronedarone, quinidine, verapamil), medicines to treat fungal infections (ketoconazole, itraconazole), medicines to prevent organ rejection after transplantation (tacrolimus, cyclosporine) antiviral or HIV medicines (lopinavir, ritonavir, glecaprevir, pibrentasvir), antibiotics (rifampicin or clarithromycin), pain reliever (aspirin, ibuprofen, diclofenac), antiepileptic drugs (carbamazepine, phenytoin).

Drug-Food Interactions: Dabigo 150 mg Capsule may interact with St. John’s wort, an herbal medicine for depression.

Drug-Disease Interactions: Use with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

Drug-Drug Interactions

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How does the drug interact with Dabigo 150 mg Capsule:
When Mifepristone is taken with Dabigo 150 mg Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Dabigo 150 mg Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabigo 150 mg Capsule:
Co-administration of dabigatron etexilate with cilostazol can increase the risk or severity of bleeding.

How to manage the interaction:
Taking dabigatron etexilate with cilostazol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as unusual bleeding or bruising, dizziness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dabigo 150 mg Capsule:
Coadministration of Mefenamic acid with Dabigatran can increase the risk or severity of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Mefenamic acid with Dabigo 150 mg Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dabigo 150 mg Capsule:
Coadministration of Dabigo 150 mg Capsule and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Dabigo 150 mg Capsule and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
Severe
How does the drug interact with Dabigo 150 mg Capsule:
Taking Dabigo 150 mg Capsule with Diflunisal can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigo 150 mg Capsule with Diflunisal together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigo 150 mg Capsule:
Taking Dabigo 150 mg Capsule with Tolmetin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigo 150 mg Capsule with Tolmetin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigo 150 mg Capsule:
Taking Dabigo 150 mg Capsule with Ketoprofen can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigo 150 mg Capsule with Ketoprofen together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigo 150 mg Capsule:
Taking Flurbiprofen with Dabigo 150 mg Capsule can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Flurbiprofen and Dabigo 150 mg Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience bleeding, feeling dizzy or lightheaded, dark or sticky stools, throwing up blood, severe headache, or feeling weak contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Dabigo 150 mg Capsule:
Taking Dabigo 150 mg Capsule with Streptokinase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigo 150 mg Capsule with Streptokinase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Dabigo 150 mg Capsule:
Coadministration of Warfarin with Dabigo 150 mg Capsule can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Dabigo 150 mg Capsule and warfarin, you can take these medicines together if prescribed by a doctor. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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DABIGATRAN-150MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN-150MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Dabigo 150 mg Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Dabigo 150 mg Capsule treatment.

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