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Hepaglan-25 Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Drug-Drug Interactions

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HeparinOritavancin
Critical

Drug-Drug Interactions

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HeparinOritavancin
Critical
How does the drug interact with Hepaglan-25 Injection 5 ml:
Using Hepaglan-25 Injection 5 ml with Oritavancin can make Hepaglan-25 Injection 5 ml less effective as a therapy.

How to manage the interaction:
Hepaglan-25 Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Hepaglan-25 Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking Alteplase with Hepaglan-25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Hepaglan-25 Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking Tenecteplase with Hepaglan-25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Hepaglan-25 Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking Ticlopidine with Hepaglan-25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Hepaglan-25 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking Mifepristone with Hepaglan-25 Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Hepaglan-25 Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Hepaglan-25 Injection 5 ml:
When Hepaglan-25 Injection 5 ml is taken with bazedoxifene the effects of Hepaglan-25 Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Hepaglan-25 Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking Abciximab with Hepaglan-25 Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Abciximab with Hepaglan-25 Injection 5 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - bleeding, bruising, vomiting, headache, dizziness, weakness, or blood in your urine or stools, it's important to contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking fondaparinux with Hepaglan-25 Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Fondaparinux with Hepaglan-25 Injection 5 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Coadministration of Hepaglan-25 Injection 5 ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Hepaglan-25 Injection 5 ml and Apixaban may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Hepaglan-25 Injection 5 ml:
Taking Hepaglan-25 Injection 5 ml with Enoxaparin may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Hepaglan-25 Injection 5 ml and Enoxaparin, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-25000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-25000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Hepaglan-25 Injection 5 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Hepaglan-25 Injection 5 ml.

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