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Spirolact 50mg Tablet

Spirolact 50mg Tablet is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. It contains Spironolactone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future. In some cases, this medication may cause common side effects, including low blood pressure, dehydration, drowsiness, dizziness, high potassium levels, low sodium levels, elevated creatinine levels, headaches, breast enlargement in males, and absence of menstrual periods in females. Before taking this medication, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medicines you are taking and any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Side effects of Spirolact 50mg Tablet
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Practice good hygiene by washing the vaginal area with water and mild soap.
  • Wear breathable cotton underwear and avoid scented products.
  • Check vaginal secretion changes, including colour, texture, amount, and smell.
  • Be aware of potential causes like infection or pregnancy.
  • Consult a doctor if secretions are unusual, or smelly with pain.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
  • If you experience a lack of energy due to liver conditions, consult your doctor to determine the underlying cause and further management.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine instead drink plenty of water.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

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Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Spirolact 50mg Tablet may interact with other blood pressure-lowering medications (metoprolol, ramipril, hydrochlorothiazide, atorvastatin), antiepileptics (carbamazepine, phenobarbital), antidepressants (alprazolam), immunosuppressants (cyclosporine), and painkillers (ibuprofen, aspirin).

Drug-Food Interactions: You are recommended not to consume alcohol along with Spirolact 50mg Tablet to avoid unpleasant side effects.

Drug-Disease Interactions: Spirolact 50mg Tablet should not be given to the people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease, or heart failure, hyperkalaemia (high potassium levels), hyponatraemia (low sodium levels), and patients with anuria (no urine output), diabetes.

SpironolactoneAmiloride
Critical
SpironolactoneEplerenone
Critical

Drug-Drug Interactions

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SpironolactoneAmiloride
Critical
How does the drug interact with Spirolact 50mg Tablet:
Coadministration of Amiloride with Spirolact 50mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Spirolact 50mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactoneEplerenone
Critical
How does the drug interact with Spirolact 50mg Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Spirolact 50mg Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAzilsartan medoxomil
Severe
How does the drug interact with Spirolact 50mg Tablet:
Coadministration of Azilsartan medoxomil with Spirolact 50mg Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking Spirolact 50mg Tablet and Azilsartan medoxomil together can result in an interaction, it can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, weakness, confusion, tingling of the hands and feet, or palpitations. Do not stop using any medications without consulting a doctor.
SpironolactonePotassium citrate
Severe
How does the drug interact with Spirolact 50mg Tablet:
Taking Spirolact 50mg Tablet with potassium citrate may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Spirolact 50mg Tablet and potassium citrate together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
SpironolactoneLithium
Severe
How does the drug interact with Spirolact 50mg Tablet:
Taking lithium and Spirolact 50mg Tablet may increase blood levels of lithium.

How to manage the interaction:
Although taking Spirolact 50mg Tablet and lithium together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as loose stools, vomiting, drowsiness, shaking, thirst, lack of coordination, or muscle weakness. Do not stop using any medications without consulting doctor.
SpironolactoneMorphine
Severe
How does the drug interact with Spirolact 50mg Tablet:
Taking Spirolact 50mg Tablet with morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Spirolact 50mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination make sure to contact a doctor. Do not stop using any medications without consulting a doctor.
SpironolactoneTelmisartan
Severe
How does the drug interact with Spirolact 50mg Tablet:
Taking Spirolact 50mg Tablet with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Spirolact 50mg Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
SpironolactoneIrbesartan
Severe
How does the drug interact with Spirolact 50mg Tablet:
Taking Irbesartan with Spirolact 50mg Tablet may increase potassium levels in the blood, which may lead to side effects.

How to manage the interaction:
Taking Irbesartan with Spirolact 50mg Tablet can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctors advise.
SpironolactoneLosartan
Severe
How does the drug interact with Spirolact 50mg Tablet:
Coadministration of Losartan with Spirolact 50mg Tablet can increase potassium levels in blood which can lead to severe conditions like kidney problems and irregular heart rhythm.

How to manage the interaction:
Taking Losartan with Spirolact 50mg Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactonePazopanib
Severe
How does the drug interact with Spirolact 50mg Tablet:
Taking Spirolact 50mg Tablet with pazopanib may significantly increase the blood levels of pazopanib. This could increase the risk of severe adverse effects.

How to manage the interaction:
Although taking Spirolact 50mg Tablet and pazopanib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, chest pain, pain in your arms, back, neck, or jaw, slurred speech or difficulty speaking, shortness of breath. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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