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Drug-Drug Interactions
Critical
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Symketo 200mg Tablet:
When Regorafenib is taken with Symketo 200mg Tablet, it can increase the levels of Regorafenib, which may lead to side effects.
How to manage the interaction:
Taking Regorafenib with Symketo 200mg Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
When Regorafenib is taken with Symketo 200mg Tablet, it can increase the levels of Regorafenib, which may lead to side effects.
How to manage the interaction:
Taking Regorafenib with Symketo 200mg Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Symketo 200mg Tablet:
Using Symketo 200mg Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.
How to manage the interaction:
Taking Symketo 200mg Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
Using Symketo 200mg Tablet with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.
How to manage the interaction:
Taking Symketo 200mg Tablet with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Symketo 200mg Tablet:
Coadministration of Lovastatin with Symketo 200mg Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.
How to manage the interaction:
Taking Symketo 200mg Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Coadministration of Lovastatin with Symketo 200mg Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.
How to manage the interaction:
Taking Symketo 200mg Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Symketo 200mg Tablet:
When Dronedarone is taken with Symketo 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Symketo 200mg Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
When Dronedarone is taken with Symketo 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Symketo 200mg Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
Critical
How does the drug interact with Symketo 200mg Tablet:
Co-administration of ticagrelor with Symketo 200mg Tablet can cause severe bleeding.
How to manage the interaction:
Taking Ticagrelor with Symketo 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of ticagrelor with Symketo 200mg Tablet can cause severe bleeding.
How to manage the interaction:
Taking Ticagrelor with Symketo 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleLomitapide
Critical
How does the drug interact with Symketo 200mg Tablet:
When Lomitapide is taken with Symketo 200mg Tablet, it may increase the risk of side effects.
How to manage the interaction:
Taking Symketo 200mg Tablet with Lomitapide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor immediately. Do not stop using any medications without talking to the doctor.
When Lomitapide is taken with Symketo 200mg Tablet, it may increase the risk of side effects.
How to manage the interaction:
Taking Symketo 200mg Tablet with Lomitapide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor immediately. Do not stop using any medications without talking to the doctor.
Critical
How does the drug interact with Symketo 200mg Tablet:
Coadministration of Ivabradine with Symketo 200mg Tablet can increase the risk or severity of side effects.
How to manage the interaction:
Taking Ivabradine with Symketo 200mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Ivabradine with Symketo 200mg Tablet can increase the risk or severity of side effects.
How to manage the interaction:
Taking Ivabradine with Symketo 200mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Symketo 200mg Tablet:
When Pimozide is taken with Symketo 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Symketo 200mg Tablet with Pimozide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
When Pimozide is taken with Symketo 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.
How to manage the interaction:
Taking Symketo 200mg Tablet with Pimozide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleVenetoclax
Critical
How does the drug interact with Symketo 200mg Tablet:
When Venetoclax is taken with Symketo 200mg Tablet, it can increase the risk of side effects.
How to manage the interaction:
Taking Symketo 200mg Tablet with Venetoclax is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. if you experience nausea, vomiting, diarrhea, fatigue, bleeding problems, and infections, consult a doctor. Do not stop using any medications without talking to a doctor.
When Venetoclax is taken with Symketo 200mg Tablet, it can increase the risk of side effects.
How to manage the interaction:
Taking Symketo 200mg Tablet with Venetoclax is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. if you experience nausea, vomiting, diarrhea, fatigue, bleeding problems, and infections, consult a doctor. Do not stop using any medications without talking to a doctor.
Critical
How does the drug interact with Symketo 200mg Tablet:
Using alfuzosin together with Symketo 200mg Tablet may significantly increase the blood levels of alfuzosin, which may result in side effects.
How to manage the interaction:
Taking Alfuzosin with Symketo 200mg Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Using alfuzosin together with Symketo 200mg Tablet may significantly increase the blood levels of alfuzosin, which may result in side effects.
How to manage the interaction:
Taking Alfuzosin with Symketo 200mg Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Consumption of grapefruit or its juice with Symketo 200mg Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Symketo 200mg Tablet.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Consumption of grapefruit or its juice with Symketo 200mg Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Symketo 200mg Tablet.
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