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Gelusil MPS Xtra Cool Syrup is used to relieve acidity-related stomach discomfort such as heartburn, indigestion, and gastritis (inflammation of the stomach). It helps reduce excess stomach acid and eases bloating and gas. It improves digestive comfort and reduces stomach irritation.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.

  • Medicine to increase platelet count (Eltrombopag)
    Potential effect: May interfere with the absorption of eltrombopag and reduce its effectiveness.
  • Anticancer medicines (Pazopanib, Gefitinib)
    Potential effect: May reduce the blood levels and effectiveness of pazopanib and gefitinib.
  • Vitamin D3 supplement (Colecalciferol)
    Potential effect: May increase the risk of toxicity when used together.
  • Calcium supplements (Calcium citrate malate)
    Potential effect: May increase aluminium levels in the blood by enhancing the effect of aluminium hydroxide, raising the risk of side effects.
  • Mineral salts (Potassium citrate, Sodium citrate)
    Potential effect: May increase aluminium hydroxide levels in the blood and increase the risk of adverse effects.
  • Anti-HIV medicine (Dolutegravir)
    Potential effect: May reduce the effectiveness of dolutegravir by affecting its absorption.

Drug-Food Interactions:

  • Alcohol: Avoid alcohol while taking Gelusil MPS Xtra Cool Syrup , as it may increase stomach acid production and worsen acidity and heartburn.

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Gelusil MPS Xtra Cool Syrup .

  • Constipation
  • Inflammatory bowel disease
  • Intestinal obstruction disorder (blocked intestine)
  • Renal dysfunction (kidney problem)
Aluminium hydroxideEltrombopag
Critical
Aluminium hydroxidePazopanib
Critical

Drug-Drug Interactions

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Aluminium hydroxideEltrombopag
Critical
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Coadministration of Eltrombopag and aluminum hydroxide may interfere with the absorption of eltrombopag and reduce its effectiveness.

How to manage the interaction:
Taking Eltrombopag with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
Aluminium hydroxidePazopanib
Critical
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Co-administration of pazopanib with Gelusil MPS Xtra Cool Syrup 200 ml can reduce the blood levels and effects of pazopanib.

How to manage the interaction:
Although there is an interaction between Pazopanib and Gelusil MPS Xtra Cool Syrup 200 ml, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Aluminium hydroxideColecalciferol
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
The combined use of aluminum hydroxide with colecalciferol may increase the risk of toxicity.

How to manage the interaction:
Co-administration of Colecalciferol with Gelusil MPS Xtra Cool Syrup 200 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like bone pain, muscle weakness, anemia, seizures, or dementia, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
Aluminium hydroxideGefitinib
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Coadministration of Gefitinib and Gelusil MPS Xtra Cool Syrup 200 ml can reduce the levels of Gefitinib in the body. This can lead to reduced treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Gefitinib and Gelusil MPS Xtra Cool Syrup 200 ml, but it can be taken if prescribed by a doctor. If you notice that your symptoms are getting worse or not improving, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Aluminium hydroxideCalcium citrate
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Co-administration of Calcium citrate with Aluminum hydroxide may increase the effects of aluminum hydroxide, which could result in too high aluminum blood levels.

How to manage the interaction:
Although there is an interaction, calcium citrate can be used with aluminum hydroxide if prescribed by the doctor. However, maintain a gap of 2-3 hours between both medicines. Do not discontinue the medication without a doctor's advice.
Aluminium hydroxideSodium citrate
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Co-administration of Gelusil MPS Xtra Cool Syrup 200 ml and Sodium citrate may increase aluminum levels and risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Sodium citrate and Gelusil MPS Xtra Cool Syrup 200 ml, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms like severe stomach pain, constipation, loss of appetite, pain when you urinate, muscle weakness, tiredness nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Aluminium hydroxideDolutegravir
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Taking dolutegravir with Gelusil MPS Xtra Cool Syrup 200 ml can reduce the effectiveness of Dolutegravir.

How to manage the interaction:
Although taking Dolutegravir and Aluminum hydroxide together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take dolutegravir at least two hours before or six hours after the Gelusil MPS Xtra Cool Syrup 200 ml dose. Do not discontinue using any medications without consulting a doctor.
Aluminium hydroxidePotassium citrate
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Taking Potassium citrate with Gelusil MPS Xtra Cool Syrup 200 ml can increase the levels of aluminum hydroxide, which may lead to side effects.

How to manage the interaction:
Co-administration of Potassium citrate and Gelusil MPS Xtra Cool Syrup 200 ml may result in an interaction, it can be taken if prescribed by the doctor. However if you experience any symptoms, consult the doctor. It is advised to separate doses of aluminum hydroxide and potassium citrate by 2 to 3 hours. Do not discontinue any medication without consulting the doctor.
Magnesium hydroxidePatiromer calcium
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Taking Gelusil MPS Xtra Cool Syrup 200 ml and Patiromer calcium may reduce the effectiveness of patiromer calcium.

How to manage the interaction:
Although taking Gelusil MPS Xtra Cool Syrup 200 ml and Patiromer calcium together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, lightheadedness, shaking of hands and legs, muscle twitching, numbness or tingling, prolonged muscle spasms, slowed breathing, irregular heartbeat, confusion contact a doctor. Do not discontinue any medications without consulting a doctor.
Magnesium hydroxideRaltegravir
Severe
How does the drug interact with Gelusil MPS Xtra Cool Syrup 200 ml:
Taking Gelusil MPS Xtra Cool Syrup 200 ml with Raltegravir may make the raltegravir less effective.

How to manage the interaction:
Taking Gelusil MPS Xtra Cool Syrup 200 ml with Raltegravir together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience any unusual symtopms. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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ALUMINIUM HYDROXIDE-250MG/5ML+DIMETHICONE-50MG/5ML+MAGNESIUM HYDROXIDE-250MG/5MLFruits

Drug-Food Interactions

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ALUMINIUM HYDROXIDE-250MG/5ML+DIMETHICONE-50MG/5ML+MAGNESIUM HYDROXIDE-250MG/5MLFruits
Common Foods to Avoid:
Oranges

How to manage the interaction:
Consumption of citrate or citric acid containing food with Gelusil MPS Xtra Cool Syrup 200 ml can increase the blood levels of aluminium, which can result in kidney damage. Avoid consumption of Gelusil MPS Xtra Cool Syrup 200 ml and citric acid containing foods at the same time. It is advised to consume Gelusil MPS Xtra Cool Syrup 200 ml at least 2-3 after consumption of Gelusil MPS Xtra Cool Syrup 200 ml.

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