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Bisobis A 5 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as a heart attack and stroke. It suppresses the contraction of blood vessels and promotes smooth blood flow. Common side effects include headache, nausea, dizziness, weakness, decreased blood pressure, and a slow heart rate. Inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Corona Remedies Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Bisobis A 5 Tablet

Bisobis A 5 Tablet is a prescription medicine used to treat high blood pressure and prevent chest pain caused by reduced blood flow to the heart. 
By managing these cardiovascular conditions, this oral tablet helps lower your long-term risk of serious complications, such as heart attacks and strokes. It works by targeting different pathways in your cardiovascular system to make it easier for your heart to pump blood.

For the best results, you must take Bisobis A 5 Tablet consistently every day at the same time, exactly as your doctor has prescribed. You can take this medication with or without food. To get the most benefit from your treatment, it is highly recommended to combine this medicine with healthy lifestyle adjustments, such as eating a low-salt diet and staying physically active.

While taking Bisobis A 5 Tablet , you may experience some mild side effects, such as dizziness, headaches, or swollen ankles. Most of these symptoms are temporary, but you must contact your doctor immediately if you experience serious issues, such as an unusually slow heartbeat, fainting, or chest pain that worsens.

Talk to your doctor before starting this medicine if you have certain health conditions, including a history of heart failure, liver damage, kidney disease, asthma, or blood circulation disorders. Do not take this if you have advanced heart block or a very slow baseline heart rate.

Bisobis A 5 Tablet can interact with other blood pressure medicines, alcohol, and smoking, which can cause your blood pressure to drop too low or increase your risk of severe side effects. If you are pregnant, breastfeeding, planning a pregnancy, or are an older adult, you must consult your doctor or pharmacist to discuss your specific safety considerations before starting treatment.
 

Uses of Bisobis A 5 Tablet

Your doctor may prescribe Bisobis A 5 Tablet to help manage the following conditions:

  • High Blood Pressure (Hypertension): Bisobis A 5 Tablet helps relax your blood vessels and regulate your heart rate, which lowers blood pressure and reduces the risk of strokes, heart attacks, and kidney failure.
  • Chronic Stable Angina (Chest Pain): Bisobis A 5 Tablet helps prevent chest pain by improving oxygen and blood flow to your heart muscle, reducing the frequency of sudden painful attacks.

Key Benefits

Bisobis A 5 Tablet is used to treat high blood pressure and certain heart conditions. It combines two medicines that work together to relax blood vessels and reduce the heart's workload, helping improve cardiovascular health.

  • Lowers High Blood Pressure: Helps reduce elevated blood pressure, lowering the risk of complications such as heart attack, stroke, and kidney damage.
  • Reduces the Heart's Workload: Slows the heart rate and relaxes blood vessels, allowing the heart to pump blood more efficiently.
  • Relieves Chest Pain: Helps reduce the frequency and severity of angina, making physical activities more comfortable.
  • Supports Heart Health: Improves overall cardiovascular function and helps protect the heart from the long-term effects of uncontrolled high blood pressure.
  • Convenient Combination Therapy: Combines two effective medicines in a single tablet, simplifying treatment and supporting better adherence to therapy.
     
Side effects of Bisobis A 5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Bisobis A 5 Tablet can be taken with or without food, but taking it after meals may help reduce the risk of dizziness or stomach upset.
  • It is advised to take Bisobis A 5 Tablet once daily at the same time each day, preferably in the morning, or as prescribed by your doctor.
  • Swallow Bisobis A 5 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Bisobis A 5 Tablet Works

Bisobis A 5 Tablet contains amlodipine and bisoprolol fumarate. It is a combination medication containing two active ingredients that work in different, complementary ways to support your heart and blood vessels. The first active component, amlodipine, is a calcium channel blocker. It works by relaxing and widening the smooth muscles of your blood vessel walls. This widening action allows blood to flow more freely throughout your body, which lowers your overall blood pressure. The second active component, bisoprolol fumarate, belongs to a class of medicines known as beta-blockers. It targets specific receptors in your heart to slow down your heart rate and reduce the force with which your heart pumps. By reducing how hard your heart has to work, this component decreases your heart's demand for oxygen, which prevents chest pain and keeps your heart rate stable. Together, these two active components help lower blood pressure, reduce the heart's workload, and improve overall heart function.
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Alcohol

Caution

You are recommended not to consume alcohol along with Bisobis A 5 Tablet as it may potentiate the blood pressure-lowering effect of Bisobis A 5 Tablet .

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Pregnancy

Caution

Consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribed only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Bisobis A 5 Tablet is not recommended in breastfeeding mothers.

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Driving

Caution

Bisobis A 5 Tablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Bisobis A 5 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Bisobis A 5 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Bisobis A 5 Tablet is not recommended in children as the safety and efficacy of Bisobis A 5 Tablet have not yet been established.

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Heart

Caution

Bisobis A 5 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Bisobis A 5 Tablet .

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Geriatrics

Caution

Bisobis A 5 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Please consult your doctor before using Bisobis A 5 Tablet .

What if I have taken an overdose of Bisobis A 5 Tablet

In case of an accidental overdose, seek immediate medical attention or contact a poison control centre. Symptoms of an overdose may include severe dizziness, fainting, extreme weakness, or an exceptionally slow heart rate.

Diet & Lifestyle Advise

  • Reduce Sodium Intake: Avoid processed foods and limit the amount of table salt you add to your meals to help naturally keep your blood pressure down.
  • Follow a Heart-Healthy Diet: Focus on whole foods, including plenty of fresh vegetables, fruits, whole grains, lean proteins, and low-fat dairy options.
  • Engage in Regular Exercise: Incorporate moderate physical activity, such as 30 minutes of brisk walking, most days of the week. Always consult your doctor before starting any new exercise routine.
  • Limit Alcohol and Avoid Tobacco: Limit your alcohol consumption, and avoid smoking entirely, as tobacco damages your blood vessels and actively raises blood pressure.
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How Soon It Starts Working

The time required for Bisobis A 5 Tablet to start to work: The effect of Bisobis A 5 Tablet is seen between 2 to 4 hours of administration.

The time for which the effects of Bisobis A 5 Tablet last: Bisobis A 5 Tablet effect lasts for 24 hours.

What if you forget to take Bisobis A 5 Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular timing. Do not take a double dose to make up for a missed one.

Storage

•Store the tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Do not stop taking this medicine abruptly: Sudden withdrawal can cause your blood pressure to spike dangerously or trigger severe chest pain. Your doctor will guide you on gradually increasing dose or tapering off if you need to stop.
  • Rise slowly: Stand up slowly from sitting or lying down to reduce the risk of dizziness, lightheadedness, or fainting.
  • Monitor your blood pressure: Keep a regular log of your blood pressure and heart rate at home to share with your doctor during check-ups.
  • Avoid driving if dizzy: Do not drive or operate machinery if you feel sleepy, lightheaded, or tired, especially when starting the medication or after a dose change.
  • Alert your healthcare team: Always inform your dentist, surgeon, or any other healthcare specialist that you are taking Bisobis A 5 Tablet before undergoing any medical procedures.
     

Drug-Drug Interactions

verifiedApollotooltip

Bisobis A 5 Tablet may interact with certain medicines, affecting its effectiveness or increasing the risk of side effects.

  • Other Blood Pressure Medicines: Taking this medicine with other drugs that lower blood pressure can cause your blood pressure to drop too low.
  • Heart Rhythm Medications: Combining this medicine with drugs that control irregular heartbeats can cause your heart rate to slow down excessively.
  • Pain Relievers (NSAIDs): Medicines like ibuprofen or naproxen can reduce the blood-pressure-lowering effectiveness of Bisobis A 5 Tablet .

Drug-Drug Interactions

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How does the drug interact with Bisobis A 5 Tablet:
Co-administration of ceritinib together with bisoprolol can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between bisoprolol and ceritinib, but it can taken together if prescribed by the doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Bisobis A 5 Tablet:
Using phenobarbital and amlodipine may drastically lower amlodipine blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with amlodipine can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bisobis A 5 Tablet:
Coadministration of amlodipine and rifampicin together may lower amlodipine blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between amlodipine and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bisobis A 5 Tablet:
Coadministration of Bisobis A 5 Tablet and carbamazepine together may significantly reduce amlodipine blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Bisobis A 5 Tablet and carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Bisobis A 5 Tablet:
When Amlodipine is taken with Fosphenytoin, it may decrease the blood levels of Amlodipine, which may make Amlodipine less effective.

How to manage the interaction:
Although taking Amlodipine and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bisobis A 5 Tablet:
Using amlodipine and rifabutin together may lower amlodipine blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between amlodipine with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bisobis A 5 Tablet:
When Bisoprolol is combined with Atenolol the severity or risk of side effects may be increased.

How to manage the interaction:
Although there may be an interaction, atenolol can be taken with bisoprolol if prescribed by the doctor. Consult the prescriber if you experience any unusual side effects. Do not discontinue the medication without consulting a doctor.
Bisoprolol + AmlodipinePotassium gluconate
Severe
How does the drug interact with Bisobis A 5 Tablet:
Co-administration of Potassium gluconate may increase the hyperkalemic (high potassium levels in the blood) activities of Bisoprolol.

How to manage the interaction:
Although there may be an interaction, Potassium gluconate can be taken with Bisoprolol if prescribed by the doctor. Consult the prescriber if you develop symptoms of hyperkalemia (high potassium) such as muscle weakness, numbness, shortness of breath, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Bisobis A 5 Tablet:
Co-administration of Bisoprolol with Fingolimod may cause excessive slowing of the heart rate that can lead to serious cardiac complications.

How to manage the interaction:
Although there may be an interaction, Bisoprolol can be taken with Fingolimod if prescribed by the doctor. Consult the prescriber if you develop dizziness, fainting, lightheadedness, shortness of breath, chest pain, or heart palpitations during treatment. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Bisobis A 5 Tablet:
Co-administration of Bisobis A 5 Tablet with Verapamil can lead to increased risk or severity of side effects.

How to manage the interaction:
Although there may be an interaction, Bisobis A 5 Tablet can be taken with verapamil if prescribed by the doctor. Consult a prescriber if you experience headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may influence the safety or effectiveness of Bisobis A 5 Tablet during treatment.

  • Grapefruit and Grapefruit Juice: Avoid grapefruit products, as they can raise the concentration of the medication in your body and increase the risk of side effects.
  • Alcohol: Avoid or limit alcohol, as it can worsen dizziness and lower your blood pressure to unsafe levels.
AMLODIPINE-5MG+BISOPROLOL FUMARATE-5MGFruit juices, Fruits
Mild

Drug-Food Interactions

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AMLODIPINE-5MG+BISOPROLOL FUMARATE-5MGFruit juices, Fruits
Mild
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit or grapefruit juice with Bisobis A 5 Tablet can increase the blood levels of amlodipine. Avoid or limit consumption of grapefruit juice.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Bisobis A 5 Tablet is used to treat high blood pressure, a chronic condition in which the force exerted by the blood against the artery wall is high.
Bisobis A 5 Tablet works by reducing the workload on the heart and relaxing the blood vessels to ensure a fluid flow of blood. Thereby, lowering high blood pressure.
Do not stop taking Bisobis A 5 Tablet without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Bisobis A 5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Bisobis A 5 Tablet .
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidneys and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Bisobis A 5 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
Bisobis A 5 Tablet may cause palpitations, a sensation that the heart is racing, pounding, or fluttering. A minor fluctuation should not be a worry; however, if palpitations continue or you begin to feel unwell, speak with your doctor.
Try not to miss a dose in the first place. If you missed a dose of Bisobis A 5 Tablet , you are advised to take it as soon as you remember. However, if it is time for the scheduled dose, skip the missed dose and take the scheduled dose. Avoid taking a double dose of Bisobis A 5 Tablet as it may lead to low blood pressure.
No, Bisobis A 5 Tablet is not habit-forming. However, it is essential to use this medication under medical supervision and follow the prescribed dosage and duration.
Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.
Taking Bisobis A 5 Tablet may cause dizziness in some individuals. This medication can temporarily drop blood pressure, resulting in lightheadedness or dizziness, especially when standing up quickly or changing positions. The vasodilation effect of amlodipine and the heart rate slowing effect of bisoprolol can both contribute to this side effect. If you experience dizziness after taking this medication, it's essential to move slowly when standing up, avoid sudden changes in position, and sit or lie down if the dizziness occurs. If the dizziness persists or worsens, consult your doctor, as they may need to adjust your dosage or recommend alternative treatments. Remember to prioritize your safety and consult your healthcare provider if you have any concerns.
Store Bisobis A 5 Tablet at room temperature, away from heat and direct sunlight. When it's no longer needed or has expired, dispose of it responsibly. Check your local waste management guidelines for instructions. Make sure it is not consumed by children, pets, and other people.
The use of Bisobis A 5 Tablet is contraindicated to certain individuals. Those with a known hypersensitivity to amlodipine, bisoprolol, or any component of Bisobis A 5 Tablet should avoid using it. Additionally, it may not recommended for patients with cardiogenic shock, heart block (second or third-degree), sick sinus syndrome, or bradycardia (heart rate < 60 beats per minute) and pulmonary oedema (a condition characterized by fluid accumulation in the lungs). Furthermore, pregnant and breastfeeding women should not use this medication, as it may harm the fetus or baby. Finally, concurrent use with certain medications, such as beta-blockers, calcium channel blockers, digoxin, and catecholamine-depleting drugs, is also contraindicated. It's essential to consult a healthcare professional to discuss individual circumstances and determine if Bisobis A 5 Tablet is safe to use.
The use of Bisobis A 5 Tablet can lead to headaches in some individuals, typically due to the vasodilation effects of amlodipine, which can cause blood vessels to widen, or the beta-blocking effects of bisoprolol. While headaches are a common side effect in around 10-20% of patients, they are usually mild and temporary. If you experience a headache while taking this medication, In that case, it's essential to consult your healthcare provider to determine the best course of action, as they can recommend strategies to manage headaches or adjust your dosage if necessary and also rule out any underlying conditions or interactions with other medications.
Common side effects of Bisobis A 5 Tablet may include headache, dizziness, palpitations, abdominal pain, oedema, ankle swelling, fatigue, cold extremities, nausea, vomiting, diarrhoea, and constipation. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.
Use caution when driving or operating heavy machinery, as Bisobis A 5 Tablet may cause drowsiness or impaired coordination.
Limit alcohol intake or avoid it, as it may potentiate the blood pressure-lowering effects of Bisobis A 5 Tablet .
Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
No, this medicine is generally not recommended during pregnancy as it can reduce blood flow to the unborn baby. If you suspect you are pregnant or are planning a pregnancy, talk to your doctor or pharmacist immediately.
Yes, one of the active components of this medicine slows down your heart rate. If your pulse drops below 50 beats per minute, or if you feel weak, tired, and dizzy, talk to your doctor or pharmacist right away.
Stopping this medicine abruptly can cause a sudden, dangerous rise in your blood pressure or trigger severe chest pain attacks. If you need to stop, your doctor will provide a safe plan to reduce your dose gradually. Talk to your doctor or pharmacist before making any changes.
You should avoid eating grapefruit or drinking grapefruit juice while taking this medicine. Grapefruit can increase the level of the medication in your body, which can make side effects like dizziness and ankle swelling worse. Talk to your doctor or pharmacist for more details.
Yes, ankle and foot swelling is a known side effect of this medicine. Elevating your legs when sitting can help. If the swelling becomes painful, severe, or is accompanied by difficulty breathing, talk to your doctor or pharmacist immediately.

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Country of origin

India

Manufacturer/Marketer address

Corona House, Block C, Mondeal Business Park, Near Gurudwara,, S. G. Highway, Thaltej, Thaltej, Ahmedabad, Gujarat 380059
Other Info - BIS0215
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