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Cyclenorm-P Tablet 6's is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Cyclenorm-P Tablet 6's may interact with anticonvulsants (carbamazepine, phenytoin), antiviral drugs (nelfinavir, ritonavir), a medicine used to treat Cushing’s syndrome (aminoglutethimide), antibiotics (co-trimoxazole, rifampicin, tetracycline), immunosuppressant (ciclosporin).

Drug-Food Interaction: Cyclenorm-P Tablet 6's may interact with St. John’s wort (herbal medicine used to treat depression). Also, limit the intake of grapefruit juice with Cyclenorm-P Tablet 6's as it may increase the levels of Cyclenorm-P Tablet 6's in the blood.  

Drug-Disease Interactions: Avoid taking Cyclenorm-P Tablet 6's if you have vaginal bleeding, blood clots, severe itching, porphyria (blood disorder), liver problems, angina (chest pain), or if you ever had a heart attack, jaundice, or pemphigoid gestationis (an itchy rash that develops into blisters). If you have asthma, migraine headaches, epilepsy (fits), kidney or heart problems, inform your doctor before taking Cyclenorm-P Tablet 6's.

NorethisteroneTelaprevir
Severe

Drug-Drug Interactions

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NorethisteroneTelaprevir
Severe
How does the drug interact with Cyclenorm-P Tablet:
Using Telaprevir and Cyclenorm-P Tablet together can increase risk of unintended pregnancy and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Telaprevir with Cyclenorm-P Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cyclenorm-P Tablet:
Co-administration of Cyclenorm-P Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Cyclenorm-P Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cyclenorm-P Tablet:
Coadministration of Acitretin with Cyclenorm-P Tablet may interfere with the contraceptive effect of Cyclenorm-P Tablet.

How to manage the interaction:
Acitretin and Cyclenorm-P Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
NorethisteroneBexarotene
Severe
How does the drug interact with Cyclenorm-P Tablet:
Coadministration of Bexarotene and Cyclenorm-P Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Cyclenorm-P Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cyclenorm-P Tablet:
Coadministration of Phenytoin and Cyclenorm-P Tablet may decrease the blood levels of Cyclenorm-P Tablet, which may make Cyclenorm-P Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Cyclenorm-P Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Cyclenorm-P Tablet:
Using Felbamate and Cyclenorm-P Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Cyclenorm-P Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cyclenorm-P Tablet:
Taking Cyclenorm-P Tablet with rifampicin can decrease the blood levels of Cyclenorm-P Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Cyclenorm-P Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneRifapentine
Severe
How does the drug interact with Cyclenorm-P Tablet:
Combining Rifapentine and norethindrone reduces the blood levels and effects of norethindrone and increases the risk of bleeding and unintended pregnancy.

How to manage the interaction:
Although there is a possible interaction between Cyclenorm-P Tablet and Rifapentine, you can take these medicines together if prescribed by your doctor. If you're having any of these symptoms like unexpected bleeding, abnormal bleeding, it's important to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cyclenorm-P Tablet:
Eslicarbazepine may reduce the effects of Cyclenorm-P Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Cyclenorm-P Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
NorethisteroneFosphenytoin
Severe
How does the drug interact with Cyclenorm-P Tablet:
Coadministration of Cyclenorm-P Tablet with Fosphenytoin can reduces the blood levels and effects of Cyclenorm-P Tablet .

How to manage the interaction:
Taking Cyclenorm-P Tablet with Fosphenytoin together can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms of abnormal bleeding while using birth control, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Cyclenorm-P Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Cyclenorm-P Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Cyclenorm-P Tablet dose.

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