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compositionComposition:DOCETAXEL-20MG
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Prescription Medicine
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DOCETEC 20MG INJECTION is an anti-cancer medicine used in the treatment of breast, lung, prostate, stomach, head/neck cancers. It works by slowing down cell growth, thus preventing the cancer cells from rapidly dividing and spreading. Common side effects include injection site reactions, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, etc.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

DOCETAXEL-20MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About DOCETEC 20MG INJECTION

DOCETEC 20MG INJECTION is a prescription chemotherapy medicine used to treat several types of advanced cancers, including breast cancer, non-small cell lung cancer, prostate cancer, gastric (stomach) or gastroesophageal junction cancer, and head and neck cancer. It works by targeting rapidly dividing cancer cells to slow down or stop their growth. This medicine is a key component in cancer treatment plans designed to manage tumor progression and improve patient outcomes.

This medicine is given as an intravenous infusion by a healthcare professional in a clinic or hospital, typically once every three weeks. Because it is injected directly into a vein, it does not have any specific food restrictions, meaning you do not need to fast before your appointment. To support your body during treatment, it is helpful to make dietary adjustments like eating small, frequent meals and drinking plenty of fluids to stay hydrated.

While undergoing treatment, many people experience common side effects such as temporary hair loss, fatigue, nausea, and changes in their nails. However, you must contact your doctor immediately if you experience more serious symptoms, such as a high fever, severe swelling in your legs, or signs of an allergic reaction during or after your infusion.

Before you begin treatment, tell your doctor if you have a history of liver problems, heart conditions, or low blood cell counts. Do not take this if you have severe liver damage, exceptionally low white blood cell levels, or a history of severe allergic reactions to this medicine or similar treatments. Your healthcare provider will perform blood tests to ensure it is safe for you to start.

This medicine can interact with other drugs, especially those that affect liver enzymes, which may change how the treatment works or increase side effects. It is best to avoid alcohol during your treatment unless your doctor advises otherwise, as alcohol may increase the risk of liver-related side effects and some formulations of DOCETEC 20MG INJECTION contain alcohol. Stopping smoking is recommended as part of your overall cancer care, although it is not a direct interaction with DOCETEC 20MG INJECTION . Pregnant women, breastfeeding mothers, and elderly patients must consult their doctor before receiving this medicine to weigh the risks and benefits.

Starting chemotherapy can feel overwhelming. Your oncology team is there to guide and support you throughout treatment, answer your questions, and help manage any side effects that arise.

Uses of DOCETEC 20MG INJECTION

Your doctor may prescribe DOCETEC 20MG INJECTION to treat several specific types of cancer. These include:

  • Breast Cancer: Helps shrink tumours and reduces the risk of the cancer returning or spreading, often used after surgery or when other treatments have not worked.
  • Non-Small Cell Lung Cancer: Used to manage and slow the progression of advanced lung cancer, particularly in cases that have not responded to other chemotherapies.
  • Prostate Cancer: Treats advanced prostate cancer that has spread to other areas of the body and is no longer responding to hormone therapies.
  • Gastric (Stomach) or Gastroesophageal Junction Cancer: Works in combination with other medicines to treat advanced gastric (stomach) or gastro-oesophageal junction cancer and help control tumour growth.
  • Head and Neck Cancer: Used to treat advanced cancers in the head and neck area, helping to reduce tumour size before other treatments like surgery or radiation.

Key Benefits

DOCETEC 20MG INJECTION helps control the growth and spread of cancer by targeting rapidly dividing cancer cells. Its benefits focus on shrinking tumours, slowing disease progression, relieving cancer-related symptoms, and improving treatment outcomes.

  • Shrinks tumours: Directly targets rapidly multiplying cancer cells. This may help reduce tumour size and relieve symptoms caused by tumour growth.
  • Slows cancer progression: Helps delay the growth and spread of cancer, allowing better control of the disease, particularly in advanced stages.
  • Relieves cancer-related symptoms: By reducing tumour burden (the total amount of cancer in the body), it can help ease symptoms such as pain, breathing difficulty, or discomfort, depending on the type and location of the cancer.
  • Supports overall treatment outcomes: Forms an important part of many cancer treatment plans, helping improve disease control, maintain quality of life, and, in appropriate patients, extend survival.
Side effects of Docetec 20mg Injection

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • DOCETEC 20MG INJECTION will be administered by a nurse or doctor.
  • Do not self-administer.

How DOCETEC 20MG INJECTION Works

DOCETEC 20MG INJECTION contains docetaxel, a chemotherapy medicine that belongs to a group of medicines called taxanes. It works by attaching to tiny structures inside cells called microtubules, which play an essential role in cell division. DOCETEC 20MG INJECTION stabilises these microtubules and prevents them from breaking down, stopping cancer cells from completing the process of cell division. As a result, the cancer cells are unable to multiply and eventually die. Because cancer cells grow and divide much faster than most normal cells, they are more affected by DOCETEC 20MG INJECTION . However, some healthy cells that also divide rapidly, such as those in the hair follicles, bone marrow, and digestive tract, may also be affected, which can lead to some of the common side effects of chemotherapy. Together, these actions help slow or stop the growth of cancer cells and support the treatment of various types of cancer.
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Alcohol

Unsafe

It is unsafe to consume alcohol while using DOCETEC 20MG INJECTION since it may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Unsafe

It is unsafe to use DOCETEC 20MG INJECTION in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using DOCETEC 20MG INJECTION .

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Breast Feeding

Unsafe

DOCETEC 20MG INJECTION is not recommended during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting DOCETEC 20MG INJECTION .

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Driving

Unsafe

DOCETEC 20MG INJECTION causes dizziness and drowsiness that may affect your ability to drive. Do not drive or operate machinery if you experience unmanageable side effects with DOCETEC 20MG INJECTION .

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Liver

Caution

Please let your doctor know if you have any history of liver diseases or hepatic impairment. Before being treated with DOCETEC 20MG INJECTION , your doctor may advise you of blood tests to check your liver functioning.

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Kidney

Caution

Please let your doctor know if you have any history of kidney diseases before starting DOCETEC 20MG INJECTION .

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Children

Unsafe

Safety and efficacy of DOCETEC 20MG INJECTION have not been established in patients younger than 18 years.

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Heart

Caution

DOCETEC 20MG INJECTION should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving DOCETEC 20MG INJECTION .

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Geriatrics

Caution

DOCETEC 20MG INJECTION should be administered with caution in elderly patients due to an increased risk of side effects. Seek medical advice if you have any concerns.

What if I have taken an overdose of DOCETEC 20MG INJECTION

Since your treatment is prepared and given by qualified medical staff in a controlled clinical environment, an overdose is extremely rare. In the unlikely event that an incorrect amount is given, or if you experience severe, immediate side effects during or shortly after your infusion, notify your healthcare team right away. They are trained to manage these situations immediately in the clinic.

Diet & Lifestyle Advise

  • Stay hydrated: Drink at least 8 to 10 glasses of water, clear broths, or herbal teas daily, especially on the days surrounding your treatment, to help flush the medicine through your kidneys and prevent dehydration.
  • Eat small, frequent meals: If you experience nausea or a loss of appetite, try eating five or six small, nutrient-rich meals throughout the day rather than three large ones to maintain your strength.
  • Protect against infections: Wash your hands frequently with soap and water, avoid crowded places, and stay away from individuals who are sick, as your body's ability to fight off infections will be temporarily lowered.
  • Care for your skin and nails: Use mild, fragrance-free soaps and moisturisers, wear loose clothing, and protect your skin with sunscreen, as this treatment makes your skin and nails more sensitive to light and irritation.
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How Soon It Starts Working

The time required for DOCETEC 20MG INJECTION to start to work: DOCETEC 20MG INJECTION ideally shows its action within less than an hour after administration. The time for which the effects of DOCETEC 20MG INJECTION last: The effect of DOCETEC 20MG INJECTION lasts for 11 hours.

What if you forget to take DOCETEC 20MG INJECTION

Because this treatment is scheduled and given by healthcare professionals in a clinic, it is highly unlikely that you will miss a dose on your own. However, if you must miss or reschedule an infusion appointment due to illness or other reasons, contact your oncology clinic immediately. They will help you reschedule your appointment to keep your treatment plan on track.

Storage

•DOCETEC 20MG INJECTION is stored, prepared, and handled only by trained healthcare professionals in a hospital or clinic.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Take your pre-medications: Always take your prescribed steroid pills exactly as directed by your doctor before your infusion to prevent severe allergic reactions and fluid buildup.
  • Monitor the injection site: Tell your nurse immediately if you feel any burning, stinging, pain, or swelling around the vein where the medicine is being injected during your infusion.
  • Check your temperature daily: Keep a reliable thermometer at home and check your temperature regularly. If you develop a fever of 100.4°F (38°C) or higher, go to the nearest emergency room immediately or follow your oncology team's emergency instructions. Do not wait to see if the fever improves.
  • Avoid getting pregnant: Use highly effective, non-hormonal birth control during your treatment and for several months after your final dose, as this medicine can cause severe harm to an unborn baby.
  • Watch for leg swelling: Track your weight and look for sudden swelling in your ankles, feet, or hands, and report these changes to your doctor right away.
  • Inform your family members or caregivers: Make sure they know the warning signs of infection, allergic reactions, and fever so they can help you seek urgent medical care if you are unable to do so yourself.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with DOCETEC 20MG INJECTION and increase the risk of side effects or alter its effectiveness:

  • Medicines that affect the way your liver breaks down drugs: Medicines such as ketoconazole, itraconazole, or certain antibiotics like erythromycin can slow down how your liver processes DOCETEC 20MG INJECTION , increasing the amount of the medicine in your blood and raising the risk of side effects. 
DocetaxelInfliximab
Severe
DocetaxelRitonavir
Severe

Drug-Drug Interactions

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DocetaxelInfliximab
Severe
How does the drug interact with Docetec 20mg Injection:
When Docetec 20mg Injection is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Docetec 20mg Injection together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
DocetaxelRitonavir
Severe
How does the drug interact with Docetec 20mg Injection:
Taking Ritonavir and Docetec 20mg Injection may significantly increase the blood levels of Docetec 20mg Injection.

How to manage the interaction:
Taking Docetec 20mg Injection with Ritonavir together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms feeling sick, having diarrhea, sores in your mouth, retaining fluids, experiencing nerve pain, numbness or tingling, muscle pain or weakness, feeling tired, dizzy or faint, having trouble with bleeding or bruising, having a fever or chills, a sore throat, muscle aches, difficulty breathing, feeling pain or burning when you pee, or bleeding contact a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelKetoconazole
Severe
How does the drug interact with Docetec 20mg Injection:
Coadministration of Ketoconazole and Docetec 20mg Injection may significantly increase the blood levels of Docetec 20mg Injection. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Docetec 20mg Injection together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelAmiodarone
Severe
How does the drug interact with Docetec 20mg Injection:
Coadministration of Amiodarone with Docetec 20mg Injection may significantly increase the blood levels of Docetec 20mg Injection.

How to manage the interaction:
Co-administration of Docetec 20mg Injection with Amiodarone can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, make sure to consult a doctor. Do not stop using any medications without talking to a doctor.
DocetaxelItraconazole
Severe
How does the drug interact with Docetec 20mg Injection:
Coadministration of Itraconazole may significantly increase the blood levels of Docetec 20mg Injection.

How to manage the interaction:
Although there is a possible interaction between Docetec 20mg Injection and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
DocetaxelThalidomide
Severe
How does the drug interact with Docetec 20mg Injection:
Taking thalidomide together with Docetec 20mg Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Docetec 20mg Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
DocetaxelVerapamil
Severe
How does the drug interact with Docetec 20mg Injection:
Taking verapamil with Docetec 20mg Injection may significantly increase the blood levels of Docetec 20mg Injection. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Docetec 20mg Injection and Verapamil together may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medication without consulting a doctor.
DocetaxelVoriconazole
Severe
How does the drug interact with Docetec 20mg Injection:
Taking Docetec 20mg Injection with Voriconazole may significantly increase the blood levels of Docetec 20mg Injection.

How to manage the interaction:
Although taking Docetec 20mg Injection and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience dizziness, fever, chills, diarrhea, sore throat, muscle pain, shortness of breath, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
DocetaxelEtanercept
Severe
How does the drug interact with Docetec 20mg Injection:
When Etanercept is used with Docetec 20mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Docetec 20mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
DocetaxelPosaconazole
Severe
How does the drug interact with Docetec 20mg Injection:
Taking Docetec 20mg Injection with posaconazole can increase the blood levels of Docetec 20mg Injection. This may increase the risk of side effects.

How to manage the interaction:
Although using Posaconazole and Docetec 20mg Injection together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience vomiting, diarrhea, mouth sores, nerve pain, numbness, tingling, muscle pain or weakness. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain foods and beverages may affect how DOCETEC 20MG INJECTION is processed in the body:

  • Grapefruit and grapefruit juice: Grapefruit can block the enzymes that break down this medicine in your body, potentially leading to higher, unsafe levels of DOCETEC 20MG INJECTION in your system.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

DOCETEC 20MG INJECTION belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers.
DOCETEC 20MG INJECTION contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.
DOCETEC 20MG INJECTION should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using DOCETEC 20MG INJECTION .
During treatment with DOCETEC 20MG INJECTION , it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.
It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.
DOCETEC 20MG INJECTION might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, DOCETEC 20MG INJECTION is not recommended. Please consult your doctor for more information.
DOCETEC 20MG INJECTION is administered through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.
DOCETEC 20MG INJECTION may cause weight loss due to common side effects such as loss of appetite, nausea, vomiting, diarrhoea, and fatigue. But, in rare cases, some patients may experience fluid retention or increased hunger, which can lead to weight gain. Consult your doctor or pharmacist for personalized guidance if you have concerns about weight changes.
The duration of DOCETEC 20MG INJECTION treatment varies depending on the type of your cancer, dose of DOCETEC 20MG INJECTION , and your response to therapy. Typically, it is administered once every 3 weeks. Your doctor will determine the total length of treatment for you based on your specific situation.
No, it is advisable not to drink alcohol while taking DOCETEC 20MG INJECTION . Drinking alcohol during treatment may cause increased dizziness and drowsiness.
No, DOCETEC 20MG INJECTION is not available in pill form. It is available in two primary dosage forms: injection and powder for injection.
Before administering DOCETEC 20MG INJECTION , certain blood tests are required to ensure safe administration. These tests include a Complete Blood Count (CBC) to check blood cell counts, blood urea nitrogen (BUN) and creatinine levels to assess kidney function, liver function tests (LFTs) to evaluate liver health, and electrolyte level checks. Additionally, other tests may be required depending on individual patient needs and medical history. These blood tests help healthcare providers assess kidney and liver function and other vital parameters to ensure that DOCETEC 20MG INJECTION can be administered safely and effectively. Your healthcare provider will determine the necessary blood tests and monitoring requirements.
Hair loss caused by DOCETEC 20MG INJECTION is often reversible. While DOCETEC 20MG INJECTION can cause hair thinning or loss, hair growth returns once treatment is stopped. However, in some cases, hair loss may be permanent. Consult your healthcare provider for guidance and support if you're concerned about hair loss.
Dexamethasone is used with DOCETEC 20MG INJECTION to avoid toxicities.
DOCETEC 20MG INJECTION is a chemotherapy medication that belongs to the class of drugs known as anti-neoplastic/anticancer drugs. It is a cytotoxic agent that prevents the cancer cells from rapidly dividing and spreading.
DOCETEC 20MG INJECTION causes dizziness and drowsiness that may affect your ability to drive. So, do not drive or operate machinery if you experience these.
The common side effects of DOCETEC 20MG INJECTION may include vomiting, constipation, changes in taste, extreme tiredness, muscle, joint, or bone pain, hair loss, nail changes, increased eye tearing, sores in the mouth and throat, and redness, dryness, or swelling at the injection site. However, these symptoms usually diminish as your body adjusts to the medication. If these symptoms worsen, please consult a doctor for relief.
DOCETEC 20MG INJECTION is generally considered safe when following your doctor's advice. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
DOCETEC 20MG INJECTION contains Docetaxel, which belongs to the anticancer drugs.
Safety and efficacy of DOCETEC 20MG INJECTION have not been established in patients younger than 18 years.
A fever of 100.4°F (38°C) or higher is considered a medical emergency during chemotherapy because your immune system may be weakened. Go to the nearest emergency room immediately or follow your oncology team's emergency instructions. A fever during chemotherapy may indicate febrile neutropenia, a serious condition caused by a very low white blood cell count that requires urgent medical treatment.
You should avoid receiving live vaccines while undergoing chemotherapy, as your weakened immune system may not be able to handle them safely. Always check with your oncology team before receiving any vaccine, including the annual flu shot. Talk to your doctor or pharmacist first.

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Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - DOC0054
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