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సంఘటన :
మెథోట్రెక్సేట్-10ఎంజి
తయారీదారు/మార్కెటర్ :
రీజెనిక్స్ డ్రగ్స్ లిమిటెడ్
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
రిటర్న్ చేయబడదు
ఇప్పటి నుండి చెల్లుబాటు అవుతుంది :
జనవరి-27
Drug-Drug Interactions
MethotrexateEtretinate
Critical
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Extrate 5mg Tablet:
Co-administration of Etretinate with Extrate 5mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Extrate 5mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Extrate 5mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Extrate 5mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Coadministration of omeprazole with Extrate 5mg Tablet may increase the levels and side effects of omeprazole.
How to manage the interaction:
Although there is a possible interaction between omeprazole and Extrate 5mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of omeprazole with Extrate 5mg Tablet may increase the levels and side effects of omeprazole.
How to manage the interaction:
Although there is a possible interaction between omeprazole and Extrate 5mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Using thalidomide together with Extrate 5mg Tablet can increase the risk of developing blood clots.
How to manage the interaction:
Although there is a possible interaction between thalidoamide and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
Using thalidomide together with Extrate 5mg Tablet can increase the risk of developing blood clots.
How to manage the interaction:
Although there is a possible interaction between thalidoamide and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Coadministration of Extrate 5mg Tablet with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of Extrate 5mg Tablet with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Coadministration of Everolimus with Extrate 5mg Tablet can increase the risk or severity of kidney disorders.
How to manage the interaction:
Taking Everolimus with Extrate 5mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Everolimus with Extrate 5mg Tablet can increase the risk or severity of kidney disorders.
How to manage the interaction:
Taking Everolimus with Extrate 5mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Coadministration of leflunomide with Extrate 5mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Extrate 5mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of leflunomide with Extrate 5mg Tablet may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Extrate 5mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Coadministration of trimethoprim with Extrate 5mg Tablet can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Coadministration of trimethoprim with Extrate 5mg Tablet can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Co-administration of Extrate 5mg Tablet with pantoprazole can increase the levels and side effects of Extrate 5mg Tablet.
How to manage the interaction:
Although there is a possible interaction between pantoprazole and Extrate 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Extrate 5mg Tablet with pantoprazole can increase the levels and side effects of Extrate 5mg Tablet.
How to manage the interaction:
Although there is a possible interaction between pantoprazole and Extrate 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexatePhenylbutazone
Severe
How does the drug interact with Extrate 5mg Tablet:
Coadministration of phenylbutazone with Extrate 5mg Tablet may increase the levels and side effects of phenylbutazone.
How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of phenylbutazone with Extrate 5mg Tablet may increase the levels and side effects of phenylbutazone.
How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Extrate 5mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Extrate 5mg Tablet:
Co-administration of Sirolimus with Extrate 5mg Tablet can increase the risk or severity of kidney damage.
How to manage the interaction:
Although there is a possible interaction between sirolimus and Extrate 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Sirolimus with Extrate 5mg Tablet can increase the risk or severity of kidney damage.
How to manage the interaction:
Although there is a possible interaction between sirolimus and Extrate 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
METHOTREXATE-5MGCaffeine containing foods/drinks
Moderate
Drug-Food Interactions
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METHOTREXATE-5MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Extrate 5mg Tablet. Avoid taking caffeine while taking Extrate 5mg Tablet. This can increase the risk or severity of side effects.
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Extrate 5mg Tablet. Avoid taking caffeine while taking Extrate 5mg Tablet. This can increase the risk or severity of side effects.
Product Substitutes
మద్యం
అసురక్షితం
Extrate 5mg Tablet తీసుకుంటున్నప్పుడు మద్యం సేవించకుండా ఉండాలని సిఫార్సు చేయబడింది.
గర్భం
అసురక్షితం
Extrate 5mg Tablet తీవ్రమైన పుట్టుకతో వచ్చే లోపాలకు కారణం కావచ్చు. మీరు గర్భవతిగా ఉన్నప్పుడు Extrate 5mg Tablet తీసుకోవాలని సిఫార్సు చేయబడలేదు.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
Extrate 5mg Tablet తల్లిపాలలోకి వెళుతుంది. Extrate 5mg Tabletతో చికిత్స పొందుతున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి.
డ్రైవింగ్
జాగ్రత్త
Extrate 5mg Tablet మైకము మరియు అలసటకు కారణం కావచ్చు; మీరు ఈ లక్షణాలను అనుభవిస్తే డ్రైవ్ చేయవద్దు లేదా భారీ యంత్రాలను నడపవద్దు.
కాలేయం
జాగ్రత్త
మీకు దీర్ఘకాలిక కాలేయ వ్యాధి ఉంటే Extrate 5mg Tablet తీసుకోవద్దు. Extrate 5mg Tablet తీసుకునే ముందు మీకు కాలేయ బలహీనత ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
కిడ్నీ
జాగ్రత్త
Extrate 5mg Tablet తీసుకునే ముందు మీకు కిడ్నీ బలహీనత ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
జాగ్రత్త
వైద్యుడు సూచించినట్లయితే మాత్రమే పిల్లలలో Extrate 5mg Tablet జాగ్రత్తగా ఉపయోగించాలి.
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