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Heplock Injection 2 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Drug-Drug Interactions

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Drug-Drug Interaction: Heplock Injection 2 ml may have interaction with pain killers (salicylic acid, ibuprofen, indomethacin, phenylbutazone, and celecoxib), dextran, anti-malarial (hydroxychloroquine), blood thinner (abciximab, eptifibatide, dipyridamole), heart medicines (digitalis), antibiotic (tetracycline), nicotine, antiallergics, or blood pressure-lowering pills (nitroglycerin)

Drug-Food Interaction: Heplock Injection 2 ml may interact with alcohol. Avoid foods rich in vitamin K like coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, brussels sprouts as they may affect the working of Heplock Injection 2 ml. It is advisable to avoid smoking and use of tobacco products and nicotine as they may reduce the effectiveness of Heplock Injection 2 ml.

Drug-Disease Interaction: Use with caution in patients with bleeding problems, low platelet count (thrombocytopenia) and thrombosis (blood clot in veins).

HeparinBazedoxifene
Critical

Drug-Drug Interactions

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How does the drug interact with Heplock Injection 2 ml:
Taking Tenecteplase with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Heplock Injection 2 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Heplock Injection 2 ml:
When Heplock Injection 2 ml is taken with bazedoxifene the effects of Heplock Injection 2 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Heplock Injection 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Mifepristone with Heplock Injection 2 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Heplock Injection 2 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Alteplase with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Heplock Injection 2 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Heplock Injection 2 ml:
Using Heplock Injection 2 ml with Oritavancin can make Heplock Injection 2 ml less effective as a therapy.

How to manage the interaction:
Heplock Injection 2 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Heplock Injection 2 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Ticlopidine with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Heplock Injection 2 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Taking Heplock Injection 2 ml with Enoxaparin may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Heplock Injection 2 ml and Enoxaparin, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Heplock Injection 2 ml:
Coadministration of Heplock Injection 2 ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Heplock Injection 2 ml and Apixaban may cause an interaction, it is still possible to take it if a doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
How does the drug interact with Heplock Injection 2 ml:
Coadministration of Ketorolac with Heplock Injection 2 ml can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ketorolac and Heplock Injection 2 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, call a doctor immediately. Do not stop using any medications without a doctor's advice.
HeparinDicoumarol
Severe
How does the drug interact with Heplock Injection 2 ml:
Coadministration of Heplock Injection 2 ml and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Heplock Injection 2 ml and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-10IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-10IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Heplock Injection 2 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Heplock Injection 2 ml.

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