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Hydoc 500 mg Capsule is used to treat head and neck cancer and sickle cell anaemia (blocking the flow of blood that causes pain and organ damage). It works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) (haemoglobin of the unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, restores the flow of blood, and protects against problems like painful sickle cell attacks. It may cause side effects such as loss of appetite (feeling unwell and stomach upset), increased bleeding tendency, nausea, upset stomach, and vomiting.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Severe

Drug-Drug Interactions

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How does the drug interact with Hydoc 500 mg Capsule:
Taking Baricitinib with Hydoc 500 mg Capsule can increase the risk of developing serious infections.

How to manage the interaction:
Although Baricitinib and Hydoc 500 mg Capsule together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Hydoc 500 mg Capsule:
Hydoc 500 mg Capsule when used in conjunction with bacitracin may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydoc 500 mg Capsule with bacitracin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hydoc 500 mg Capsule:
Hydoc 500 mg Capsule when used with leflunomide may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydoc 500 mg Capsule with leflunomide, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideRopivacaine
Severe
How does the drug interact with Hydoc 500 mg Capsule:
Ropivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydoc 500 mg Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydoc 500 mg Capsule and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hydoc 500 mg Capsule:
Levobupivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydoc 500 mg Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydoc 500 mg Capsule and levobupivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hydoc 500 mg Capsule:
Taking Bupivacaine and Hydoc 500 mg Capsule may cause methemoglobinemia (a rare disorder in which the iron in the hemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately).

How to manage the interaction:
Although taking Hydoc 500 mg Capsule and bupivacaine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hydoc 500 mg Capsule:
Hydoc 500 mg Capsule when used together with infliximab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydoc 500 mg Capsule with infliximab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Hydoc 500 mg Capsule:
Taking Hydoc 500 mg Capsule with natalizumab, especially taking both simultaneously, may raise the risk of serious infections, which may lead to infections like progressive multifocal leukoencephalopathy (PML), an uncommon but dangerous viral infection of the brain that can result in impairment.

How to manage the interaction:
Co-administration of Hydoc 500 mg Capsule with natalizumab can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you are experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. If you have growing weakness on one side of your body, awkwardness of limbs, visual disruption, disorientation, or changes in thinking, memory, or personality, inform your doctor.
Severe
How does the drug interact with Hydoc 500 mg Capsule:
Prilocaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydoc 500 mg Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydoc 500 mg Capsule and Prilocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Hydoc 500 mg Capsule:
Hydoc 500 mg Capsule when used in conjunction with etanercept may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydoc 500 mg Capsule with etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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