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Indocap SR Capsule is used to relieve symptoms caused by osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, such as stiffness, swelling and joint pain. It is also used to treat acute gouty arthritis, musculoskeletal pain, lower back pain, period pain, and pain following joint and bone surgery. It contains Indomethacin, which works by reducing the production of prostaglandins (chemicals) that are produced at injury sites and cause pain and swelling. In some cases, you may experience certain common side effects, such as headache, dizziness, diarrhoea, vomiting, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Indocap SR Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Eat fiber-rich foods like fruits, whole grains, and vegetables as a part of your diet.
  • Minimize fasting, intense physical exercises, smoking and better to avoid drinking alcohol to reduce symptoms.
  • Maintain a normal routine by having three meals a day and staying hydrated.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

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Drug-Drug Interactions

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Drug-Drug Interactions: Indocap SR Capsule may have interaction with ibuprofen, naproxen, and aspirin (used to relieve pain), duloxetine (used to treat depression), metoprolol (used to treat high blood pressure), celecoxib, and prednisone (used to treat arthritis).

Drug-Food Interactions: Avoid consuming alcohol along with Indocap SR Capsule as it could lead to increased drowsiness and dizziness. It could also elevate the risk of stomach bleeding.

Drug-Disease Interactions: Indocap SR Capsule should not be given in patients with heart failure, fluid retention (oedema), asthma, gastrointestinal toxicity, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), rash, platelet aggregation inhibition, CNS problems, kidney and liver toxicity.

Drug-Drug Interactions

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How does the drug interact with Indocap SR Capsule:
Co-administration of Indomethacin with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Indocap SR Capsule with Cidofovir is not recommended as it can lead to an interaction, it can be used if prescribed by a doctor. However, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, shortness of breath, cramping in the muscles, weakness, confusion, and irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Indocap SR Capsule:
Co-administration of Ketorolac together with Indomethacin may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, and ulcers.

How to manage the interaction:
Taking Indocap SR Capsule with Ketorolac is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Indocap SR Capsule:
Taking indomethacin with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between fondaparinux and Indocap SR Capsule, it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Indocap SR Capsule:
Co-administration of Methotrexate with Indomethacin can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Methotrexate and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with Indocap SR Capsule:
Co-administration of Human immunoglobulin with Indocap SR Capsule may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Indomethacin can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, breathing difficulty, muscle cramps, tiredness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Indocap SR Capsule:
Co-administration of Indomethacin with Tenofovir disoproxil can increase the risk of developing kidney injury.

How to manage the interaction:
There may be a possibility of interaction between Tenofovir disoproxil and Indocap SR Capsule, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, weakness, and irregular heartbeat, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Indocap SR Capsule:
Coadministration of Flucytosine with Indomethacin can increase the risk of developing infections.

How to manage the interaction:
Although there is a possible interaction between Flucytosine and Indocap SR Capsule, you can take these medicines together if prescribed by your doctor. Contact a doctor if you experience fever, muscle ache, sore throat, or shortness of breath. Do not stop using any medications without a doctor's advice.
How does the drug interact with Indocap SR Capsule:
Co-administration of Indocap SR Capsule with Naproxen can increase the risk or severity of gastric bleeding, ulceration, and perforation leading to serious blood loss.

How to manage the interaction:
Taking Indocap SR Capsule with Naproxen together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Indocap SR Capsule:
The combined use of Indocap SR Capsule and mefenamic acid can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indocap SR Capsule with Mefenamic acid together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
IndometacinValdecoxib
Severe
How does the drug interact with Indocap SR Capsule:
The combined use of Indocap SR Capsule and valdecoxib can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and perforation.

How to manage the interaction:
There may be a possibility of interaction between Indocap SR Capsule and Valdecoxib, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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