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Lefno-10 Tablet 10's
Lefno-10 Tablet 10's
Lefno-10 Tablet 10's

Lefno-10 Tablet is used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. It contains Leflunomide, which suppresses the activated immune system to reduce pain, inflammation and swelling. This medicine may cause side effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Lefno-10 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug-Drug Interactions

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LeflunomideAlectinib
Severe
LeflunomideAmbrisentan
Severe

Drug-Drug Interactions

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LeflunomideAlectinib
Severe
How does the drug interact with Lefno-10 Tablet:
Taking alectinib with Lefno-10 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Lefno-10 Tablet and alectinib, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
LeflunomideAmbrisentan
Severe
How does the drug interact with Lefno-10 Tablet:
Taking Lefno-10 Tablet and ambrisentan can lead to or increase the risk or severity of developing liver problems.

How to manage the interaction:
Although there is an interaction between Lefno-10 Tablet and ambrisentan, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
LeflunomideGlimepiride
Severe
How does the drug interact with Lefno-10 Tablet:
Co-administration of Lefno-10 Tablet may increase the blood levels and effects of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, Glimepiride can be taken with Lefno-10 Tablet if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
LeflunomideIdarubicin
Severe
How does the drug interact with Lefno-10 Tablet:
Taking Idarubicin and Lefno-10 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Idarubicin can be taken with Lefno-10 Tablet, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
LeflunomideCiclosporin
Severe
How does the drug interact with Lefno-10 Tablet:
Using Lefno-10 Tablet together with ciclosporin can increase the risk of side effects

How to manage the interaction:
Co-administration of ciclosporin with Lefno-10 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience contact a doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, or pain during urination. Do not stop using any medications without talking to a doctor.
LeflunomideBelinostat
Severe
How does the drug interact with Lefno-10 Tablet:
Combining Belinostat with Lefno-10 Tablet can increase the risk of negative side effects.

How to manage the interaction:
Co-administration of Lefno-10 Tablet with Belinostat can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs of liver damage, complications, infection, or any other symptoms like fever, chills, diarrhea, sore throat, muscle aches, or shortness of breath, contact your doctor right away. Other symptoms to watch out for include weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-coloured urine, or bleeding. Do not stop using any medications without talking to your doctor.
LeflunomideCyclophosphamide
Severe
How does the drug interact with Lefno-10 Tablet:
Taking Cyclophosphamide with Lefno-10 Tablet may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Cyclophosphamide can be taken with Lefno-10 Tablet if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
LeflunomideDuloxetine
Severe
How does the drug interact with Lefno-10 Tablet:
Coadministration of duloxetine and Lefno-10 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Duloxetine with Cyclobenzaprine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience fever, chills, joint pain or swelling, itching, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
LeflunomideFebuxostat
Severe
How does the drug interact with Lefno-10 Tablet:
Coadministration of febuxostat with Lefno-10 Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Febuxostat with Lefno-10 Tablet can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
LeflunomideInfliximab
Severe
How does the drug interact with Lefno-10 Tablet:
Combining Infliximab with Lefno-10 Tablet can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Lefno-10 Tablet with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, burning, paleness, fatigue, dizziness, lightheadedness, and bruising or bleeding when you pee, contact a doctor right away. Do not discontinue any medications without first consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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