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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with LIPAGE F TABLET :

• Blood thinners (like warfarin): LIPAGE F TABLET may increase the effects of these medications, raising your risk of bleeding. Your doctor may need to adjust your blood thinner dose.
• Other lipid-lowering drugs (like gemfibrozil): Combining these with LIPAGE F TABLET significantly increases the risk of severe muscle damage (myopathy or rhabdomyolysis).
• Immunosuppressants (like cyclosporine): Taking these together can increase the levels of LIPAGE F TABLET in your blood, raising the risk of serious side effects.
• Colchicine: Using this gout medication alongside LIPAGE F TABLET can increase your risk of muscle pain and weakness.

Drug-Food Interactions

The following foods and beverages may interact with LIPAGE F TABLET and affect its absorption, safety, or effectiveness:

• Grapefruit and grapefruit juice: Grapefruit is known to interact with some statin medicines. However, this interaction is not considered clinically significant with rosuvastatin. If you regularly consume grapefruit products, discuss this with your doctor to determine whether any dietary changes are needed.
• High-fat meals: Taking LIPAGE F TABLET with a meal helps improve the absorption of the fenofibrate component, ensuring the medication works effectively.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking LIPAGE F TABLET , as it may worsen your condition or cause complications:

• Liver disease: Do not take LIPAGE F TABLET if you have active liver disease or unexplained, persistent elevations in liver enzymes, as it may cause further liver damage.
• Kidney disease: Severe kidney impairment can prevent the medicine from clearing your body properly, increasing the risk of toxicity. Your doctor may need to adjust your treatment or choose an alternative.
• Gallbladder disease: LIPAGE F TABLET may increase cholesterol excretion into the bile, potentially leading to the formation of gallstones. Avoid use if you have pre-existing gallbladder disease.