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Oline Plus Tablet is used to treat schizophrenia and bipolar disorder (manic depression). It contains Fluoxetine and Olanzapine which work by restoring the balance of certain natural substances in the brain. In some cases, this medicine may cause side effects such as drowsiness, lightheadedness, restlessness, irritability, tremors, dry mouth, constipation, and increased appetite. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Oline Plus Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

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Drug-Drug Interactions

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Drug-Drug Interactions: Oline Plus Tablet may interact with other benzodiazepines or anti-anxiety drugs (lorazepam and diazepam) and opioid analgesics (tramadol and codeine).

Drug-Food Interactions: Oline Plus Tablet may interact with alcohol, increasing drowsiness.

Drug-Disease Interactions: Oline Plus Tablet should be used with caution in patients with dementia, CNS (central nervous system) depression, obesity, eye problems, acute alcohol intoxication (change in mental behaviour after alcohol consumption), brain stroke, heart diseases, hyperlipidemia (lipid alterations), hyperglycemia/diabetes, liver disease, kidney problems, epilepsy, and parkinsonism (brain disorder).

Olanzapine + FluoxetinePotassium citrate
Critical

Drug-Drug Interactions

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Olanzapine + FluoxetinePotassium citrate
Critical
How does the drug interact with Oline Plus Tablet:
Taking Oline Plus Tablet with Potassium citrate can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although co-administration of Oline Plus Tablet and Potassium citrate leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oline Plus Tablet:
Taking Oline Plus Tablet with Potassium chloride (oral form) can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Although co-administration of Oline Plus Tablet and Potassium chloride leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oline Plus Tablet:
Co-administration of metoclopramide with Oline Plus Tablet can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Oline Plus Tablet and metoclopramide, you can take these medicines if prescribed by a doctor. However, if you experience any symptoms like muscle movements which are not controllable, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, jitteriness, restlessness, or foot tapping, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oline Plus Tablet:
Combining Oline Plus Tablet with Disopyramide can increase the risk of irregular heart beat.

How to manage the interaction:
Taking Oline Plus Tablet with Disopyramide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of the symptoms like loose stools, vomiting, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heart beat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oline Plus Tablet:
Using Oline Plus Tablet together with Linezolid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Linezolid and Oline Plus Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, dizziness, drowsiness, severe headache,, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness,stomach pain, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Oline Plus Tablet:
Using Oline Plus Tablet together with Phenelzine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Phenelzine and Oline Plus Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, dizziness, drowsiness, severe headache, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach pain, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
Olanzapine + FluoxetineDihydroergotamine
Severe
How does the drug interact with Oline Plus Tablet:
Using Oline Plus Tablet together with Dihydroergotamine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Dihydroergotamine and Oline Plus Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, dizziness, drowsiness, severe headache, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach pain, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oline Plus Tablet:
Taking diazepam together with Oline Plus Tablet can cause severe side effects.

How to manage the interaction:
Combining Oline Plus Tablet and Diazepam can lead to an interaction, it can be taken if a doctor has suggested it. If you experience any symptoms like dizziness, fainting, drowsiness, rapid breathing, weakness or difficulty in speaking, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Oline Plus Tablet:
Using Oline Plus Tablet together with Venlafaxine can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Venlafaxine and Oline Plus Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, dizziness, drowsiness, severe headache, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach pain, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Oline Plus Tablet:
Combining Oline Plus Tablet with Dronedarone can increase the risk of irregular heart beat.

How to manage the interaction:
Taking Oline Plus Tablet with Dronedarone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of the symptoms like loose stools, vomiting, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heart beat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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