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Oxacin TZ Tablet

Oxacin TZ Tablet is indicated in the treatment of bacterial and parasitic infections. It is used to treat a wide variety of infections which are caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes and protozoa. It contains Ciprofloxacin and Tinidazole, which kills bacteria and parasites that are responsible for causing infections. In some cases, you may experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Oxacin TZ Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug-Drug Interactions

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CiprofloxacinQuinidine
Critical
CiprofloxacinSotalol
Critical

Drug-Drug Interactions

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CiprofloxacinQuinidine
Critical
How does the drug interact with Oxacin TZ Tablet:
When Oxacin TZ Tablet is taken with Quinidine, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Oxacin TZ Tablet with Quinidine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinSotalol
Critical
How does the drug interact with Oxacin TZ Tablet:
Coadministration of sotalol together with Oxacin TZ Tablet can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Sotalol with Oxacin TZ Tablet is generally avoided as it can result in an interaction, it can be taken together if prescribed by a doctor. However, consult the doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty. Do not discontinue any medications without consulting a doctor.
CiprofloxacinFlibanserin
Critical
How does the drug interact with Oxacin TZ Tablet:
When Flibanserin is taken with Oxacin TZ Tablet, it can cause extreme drowsiness and reduces blood pressure that can lead to dizziness, lightheadedness, fainting.

How to manage the interaction:
Taking Oxacin TZ Tablet with Flibanserin is not recommended, but it can be taken if prescribed by the doctor. It is advised to take flibanserin at bedtime to reduce the risk of side effects
CiprofloxacinThioridazine
Critical
How does the drug interact with Oxacin TZ Tablet:
Combining Oxacin TZ Tablet with Thioridazine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Oxacin TZ Tablet with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinTizanidine
Critical
How does the drug interact with Oxacin TZ Tablet:
Coadministration of Oxacin TZ Tablet and Tizanidine together can increase the risk of side effects.

How to manage the interaction:
Using Oxacin TZ Tablet and Tizanidine together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
CiprofloxacinDronedarone
Critical
How does the drug interact with Oxacin TZ Tablet:
When Dronedarone is taken with Oxacin TZ Tablet, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Oxacin TZ Tablet with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinAmiodarone
Critical
How does the drug interact with Oxacin TZ Tablet:
Taking Amiodarone and Oxacin TZ Tablet may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone with Oxacin TZ Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
CiprofloxacinZiprasidone
Critical
How does the drug interact with Oxacin TZ Tablet:
Coadministration of Oxacin TZ Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Oxacin TZ Tablet with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
CiprofloxacinProcainamide
Critical
How does the drug interact with Oxacin TZ Tablet:
Using Oxacin TZ Tablet with Procainamide can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Oxacin TZ Tablet with Procainamide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
CiprofloxacinHalofantrine
Critical
How does the drug interact with Oxacin TZ Tablet:
Using Oxacin TZ Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Oxacin TZ Tablet with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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CIPROFLOXACIN-500MG+TINIDAZOLE-600MGCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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CIPROFLOXACIN-500MG+TINIDAZOLE-600MGCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Using caffeine together with ciprofloxacin may increase the effects of caffeine. Taking dairy products such as milk, yogurt, or calcium-fortified foods can make the medication less effective. Avoid taking caffeine with ciprofloxacin, as it causes effects. Contact your doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate. Avoid taking milk, yogurt, or calcium-fortified foods. You could interrupt the feeding for 1 hour before and 2 hours after the ciprofloxacin dose. Do not stop using any medications without talking to your doctor

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