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compositionComposition:PREDNISOLONE-40MG
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Preda-Met 40 mg Injection is used to treat symptoms associated with allergic reactions or inflammatory conditions. This medicine contains prednisolone, a corticosteroid that works by inhibiting the production of certain chemical messengers that cause inflammation. Thus, helps reduce swelling, redness, and itching. Let your doctor informed about your complete medical and medication history.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

PREDNISOLONE-40MG

Manufacturer/Marketer :

AAA Pharma Trade Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Preda-Met 40 mg Injection

Preda-Met 40 mg Injection is an injectable medication used to treat severe swelling, redness, and pain caused by a wide range of inflammatory and immune-system disorders. It is commonly prescribed to manage intense allergic reactions, severe flare-ups of arthritis, and acute breathing difficulties. This medication works quickly to target overactive immune responses that cause damage inside the body.

Because this medicine is given as an injection, the timing and frequency of your doses will be carefully managed by your healthcare provider to ensure maximum benefit. For best results, it is important to keep all of your scheduled medical appointments and follow a low-sodium, nutrient-rich diet to help control fluid buildup. Your doctor will determine how long you need this treatment based on how your body responds.

While taking Preda-Met 40 mg Injection, you may experience some common side effects like fluid retention, minor mood changes, or a slight increase in blood sugar. Most mild symptoms resolve as your body adjusts, but you should contact your doctor immediately if you experience severe symptoms like extreme muscle weakness, vision changes, or signs of an infection.

Do not take this if you have a known allergy to any of its ingredients or if you are currently fighting a widespread fungal infection. Before starting treatment, tell your doctor if you have a history of diabetes, high blood pressure, osteoporosis, or stomach ulcers, as this medicine may make these conditions harder to manage.

This medicine can interact with several other products, including blood thinners, certain pain relievers, and live vaccines, which may increase your risk of complications. You should also talk to your doctor or pharmacist if you are pregnant, planning to become pregnant, breastfeeding, or if you are an older adult, as special safety precautions may be required.

Although Preda-Met 40 mg Injection is more commonly prescribed as an oral medicine, this article specifically refers to the injectable (parenteral) formulation, which is used when rapid treatment is needed or when oral administration is not appropriate.

Uses of Preda-Met 40 mg Injection

Preda-Met 40 mg Injection is used to rapidly control severe inflammation, allergic reactions, and overactive immune responses when prompt treatment is required.

  • Severe allergic reactions: Helps control severe allergy symptoms such as swelling, hives, and breathing difficulties when rapid action is needed.
  • Inflammatory arthritis: Reduces severe joint pain, swelling, and stiffness during acute flare-ups of rheumatoid arthritis or gout.
  • Acute asthma exacerbations: Relieves severe asthma attacks by opening up the airways and reducing inflammation quickly.
  • Autoimmune disorders: Helps manage flare-ups in conditions like systemic lupus erythematosus where the body's immune system attacks its own tissues.
  • Inflammatory skin and eye conditions: Controls intense swelling and redness in severe skin disorders or eye inflammation.

Key Benefits

Preda-Met 40 mg Injection provides rapid control of severe inflammation and immune reactions, helping relieve symptoms quickly and prevent further complications.

  • Fast-acting relief: Because Preda-Met 40 mg Injection is injected directly into the body, it bypasses the digestive system. This allows the medication to work rapidly to bring severe inflammation and swelling under control, offering quicker relief than oral alternatives during emergencies.
  • Restored joint mobility: By rapidly reducing intense joint pain and swelling, this medication helps you move more comfortably and return to daily activities faster. It is particularly beneficial during severe arthritis flare-ups that make movement difficult.
  • Critical breathing support: In emergency respiratory situations, it quickly calms airway irritation and swelling. This helps open up your airways, making it much easier to breathe during severe asthma attacks or allergic reactions.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Preda-Met 40 mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Preda-Met 40 mg Injection Works

Preda-Met 40 mg Injection contains prednisolone, a corticosteroid that helps reduce inflammation and suppress an overactive immune response. Preda-Met 40 mg Injection works by binding to glucocorticoid receptors inside cells, where it suppresses the production of inflammatory mediators such as cytokines and prostaglandins while reducing the activity of the immune system. This helps decrease redness, swelling, heat, pain, and other symptoms caused by excessive inflammation. Together, these actions help prevent further tissue damage, relieve inflammation, and support the healing process in a wide range of inflammatory, allergic, and autoimmune conditions.
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Alcohol

Caution

No interaction was found. However, it is advisable not to take or limit alcohol as a precautionary measure.

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Pregnancy

Caution

Preda-Met 40 mg Injection is not recommended for use in pregnancy unless clearly necessary. Inform your doctor if you are pregnant or suspect, or planning pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Preda-Met 40 mg Injection.

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Breast Feeding

Safe if prescribed

Preda-Met 40 mg Injection is considered safe to be used during breastfeeding. If you are breastfeeding inform your doctor before receiving this injection. Your doctor will weigh the benefits and potential risks before prescribing Preda-Met 40 mg Injection.

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Driving

Caution

Preda-Met 40 mg Injection has no or insignificant effect on one's ability to drive or operate machinery. In rare cases, Preda-Met 40 mg Injection may cause blurred vision or other visual disturbances. If you experience these symptoms, do not drive or operate machinery until you are alert.

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Liver

Caution

Tell your doctor before receiving the Preda-Met 40 mg Injection if you have a history of liver diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Preda-Met 40 mg Injection.

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Kidney

Caution

Tell your doctor before receiving the Preda-Met 40 mg Injection if you have a history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Preda-Met 40 mg Injection.

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Children

Caution

Preda-Met 40 mg Injection is generally not recommended for use in children because it can cause growth and development delays as well as severe headaches with blurred vision or temporary visual problems. Before prescribing this medication to your child, your paediatrician may weigh the benefits and risks.

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Heart

Consult your doctor

Preda-Met 40 mg Injection can be used in patients with heart conditions, but it carry risks such as fluid retention, elevated blood pressure, and increased cardiovascular disease risk even at low doses. It's crucial to consult your doctor to determine if the benefits outweigh the risks in your specific case.

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Geriatrics

Caution

Geriatric patients can receive Preda-Met 40 mg Injection, but it may be more vulnerable to side effects like osteoporosis, fluid retention, and blood sugar changes. It's important to use it under close medical supervision with tailored dosing and regular monitoring.

What if I have taken an overdose of Preda-Met 40 mg Injection

An overdose is unlikely when the injection is administered by a healthcare professional. However, if you suspect an overdose or experience severe symptoms like extreme muscle weakness, easy bruising, or changes in your heart rate, seek immediate medical attention or call a poison control centre right away.

Diet & Lifestyle Advise

  • Limit sodium intake: Reduce the amount of salt in your meals to help prevent fluid retention and swelling, which are common when using this medicine.
  • Support bone health: Focus on eating foods rich in calcium and vitamin D, such as leafy greens, dairy products, or fortified alternatives, to help protect your bones during treatment.
  • Monitor blood sugar: If you have diabetes, check your blood sugar levels regularly, as this medication can raise glucose levels and may require you to adjust your diabetes treatment.
  • Avoid active infections: Stay away from people who are sick with contagious illnesses, such as chickenpox or measles, because this medicine can temporarily lower your body's ability to fight off infections.
  • Engage in gentle exercise: Perform light, weight-bearing activities like walking to help maintain muscle strength and bone density, provided your doctor agrees it is safe for you.
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How Soon It Starts Working

The time required for Preda-Met 40 mg Injection to start to work: The onset time of Preda-Met 40 mg Injection has not been clinically established. The time for which the effects of Preda-Met 40 mg Injection last: The duration of Preda-Met 40 mg Injection’s effect is clinically not established.

What if you forget to take Preda-Met 40 mg Injection

If you miss an appointment for your injection, contact your healthcare provider immediately to reschedule. If you are self-injecting at home and miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and return to your regular schedule. Do not double the dose to catch up.

Storage

• Store Preda-Met 40 mg Injection vials at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the vial before use: Always check that the solution is clear. Do not use it if it appears cloudy, discoloured, or contains visible particles.
  • Use sterile equipment every time: Never reuse needles, syringes, or single-dose vials, as this can lead to serious infections.
  • Rotate injection sites: Change the injection site with each dose to help prevent skin irritation and damage to the underlying tissues.
  • Carry a medical alert identification: Carry a steroid treatment card or wear a medical alert bracelet so healthcare professionals know you are receiving corticosteroid therapy during emergencies.
  • Avoid live vaccines: Do not receive live vaccines, such as the MMR or shingles vaccine, unless your doctor advises it, as Preda-Met 40 mg Injection may weaken your immune response.
  • Do not stop treatment suddenly: Long-term use can suppress your body's hypothalamic-pituitary-adrenal (HPA) axis, reducing your body's natural steroid production. Stopping treatment abruptly may lead to adrenal insufficiency (adrenal crisis), which can be life-threatening. Always follow your doctor's tapering schedule.

Drug-Drug Interactions

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The following medicines may interact with Preda-Met 40 mg Injection:

  • Blood thinners (such as warfarin): Taking these medicines together may increase the risk of bleeding and require closer monitoring.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Pain relievers such as ibuprofen or aspirin may increase the risk of stomach irritation, ulcers, or gastrointestinal bleeding when used with Preda-Met 40 mg Injection.
  • Diabetes medicines: Preda-Met 40 mg Injection may reduce the effectiveness of insulin and oral diabetes medicines, requiring adjustments to your diabetes treatment.
Critical

Drug-Drug Interactions

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How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Co-administration of Preda-Met 40 mg Injection 10 ml and Vigabatrin together can increase the risk or severity of side effects associated with vision loss.

How to manage the interaction:
Taking Preda-Met 40 mg Injection 10 ml with Vigabatrin is not recommended, it can be taken if prescribed by the doctor. Regular eye check ups are advised during this treatment. Do not discontinue any medication without consulting a doctor.
Critical
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Co-administration of Methylphenidate with Iohexol may increase the risk or severity of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Preda-Met 40 mg Injection 10 ml with Iohexol is not recommended, please consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
When Preda-Met 40 mg Injection 10 ml is taken with Mifepristone, it may decrease the levels of Preda-Met 40 mg Injection 10 ml, which may be less effective in treating your condition.

How to manage the interaction:
Taking Preda-Met 40 mg Injection 10 ml with Mifepristone is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Co-administration of Preda-Met 40 mg Injection 10 ml and Gatifloxacin together can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Preda-Met 40 mg Injection 10 ml and Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Using baricitinib together with Preda-Met 40 mg Injection 10 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Preda-Met 40 mg Injection 10 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, severe abdominal pain, nausea, or vomiting, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Coadministration of posaconazole with Preda-Met 40 mg Injection 10 ml may significantly increase the blood levels of Preda-Met 40 mg Injection 10 ml, which may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Preda-Met 40 mg Injection 10 ml, it can be taken if a doctor has advised it. However, if you experience swelling, weight gain, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, irregular menstruation, excessive facial or body hair growth, abnormal body fat distribution, especially in the face, neck, back, and waist, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Co-administration of Desmopressin with Preda-Met 40 mg Injection 10 ml together may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Desmopressin and Preda-Met 40 mg Injection 10 ml can cause an interaction, but it can be taken if advised by a doctor. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood), Contact a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Taking Preda-Met 40 mg Injection 10 ml with ritonavir may significantly increase the blood levels of Preda-Met 40 mg Injection 10 ml.

How to manage the interaction:
Although taking Preda-Met 40 mg Injection 10 ml and Ritonavir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience swelling, palpitations, sweating, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, menstrual irregularities, or excessive growth of facial or body hair contact a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Co-administration of Bempedoic acid with Preda-Met 40 mg Injection 10 ml can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Preda-Met 40 mg Injection 10 ml if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Preda-Met 40 mg Injection 10 ml:
Co-administration of Levofloxacin with Preda-Met 40 mg Injection 10 ml may increase the risk of tendinitis(inflammation of the thick fibrous cords that attach muscle to bone).

How to manage the interaction:
Concomitant administration of levofloxacin with Preda-Met 40 mg Injection 10 ml can result in an interaction, it can be taken if a doctor has advised it. If you experience pain, swelling, or inflammation in a tendon location such as the back of the ankle, shoulder, biceps, hand, or thumb, call a doctor immediately. You should also refrain from exercising or using the afflicted region until a doctor gives you further instructions. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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The following food or drink may interact with Preda-Met 40 mg Injection:

  • Caffeine: Excessive caffeine intake may increase restlessness or difficulty sleeping while receiving Preda-Met 40 mg Injection. Although there is no significant direct interaction, limiting excessive caffeine intake may help reduce these additive effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CORTICOSTEROIDS]

FAQs

Preda-Met 40 mg Injection belongs to the corticosteroid drug class. It is used to treat symptoms associated with allergic reactions or inflammatory conditions. Preda-Met 40 mg Injection is primarily used to treat arthritis, tennis elbow, and golfer's elbow, which cause swelling and pain in the joints and tendons.
Preda-Met 40 mg Injection contains prednisolone, a corticosteroid medicine. It works by inhibiting the transmission of certain chemical messengers in the body that cause inflammation and allergic conditions; thus, it effectively treats various medical conditions associated with allergic and inflammatory conditions.
Corticosteroid medications such as Preda-Met 40 mg Injection can alter how your body processes carbs and sugars (glucose). They can elevate your blood sugar by preventing insulin from working. If you have diabetes your doctor may monitor your blood glucose levels regularly while you are on treatment with this medicine.
Preda-Met 40 mg Injection is not recommended for treating viral infections such as measles, chickenpox, shingles, or any other viral conditions.
Complete the entire course of treatment with Preda-Met 40 mg Injection even if you feel better after receiving a few doses as abrupt stopping may lead to undesirable effects.
While taking Preda-Met 40 mg Injection, do not receive a "live" vaccine (including measles, mumps, polio, chickenpox) as the vaccine may not work, and you may develop the disease again.
Because it is given as an injection, Preda-Met 40 mg Injection typically begins to work quickly, often within a few hours, to help reduce severe swelling and inflammation. Talk to your doctor if you do not feel better.
Mild redness or soreness can occur at the injection site. However, if you notice spreading redness, severe swelling, warmth, or pus, contact your doctor immediately, as these may be signs of an infection.
Yes, this medicine can cause water retention and a larger appetite, which may lead to weight gain. Following a low-sodium diet and staying active can help manage this. Talk to your doctor if you are concerned.
This medicine should only be used during pregnancy or breastfeeding if the benefits outweigh the risks. Talk to your doctor to understand how this medication might affect you and your baby.
It is best to avoid or limit alcohol while using Preda-Met 40 mg Injection, as both can irritate your stomach lining and increase your risk of developing stomach ulcers or bleeding. Talk to your doctor or pharmacist for personalised advice.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

E-11, MOTI NAGAR , NEW DELHI-110015
Other Info - PRE1021
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