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compositionComposition:REPAGLINIDE-0.5MG+VOGLIBOSE-0.3MG
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Prescription Medicine
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Repaone V-0.5/0.3 Tablet 10's is used to treat type 2 diabetes. It works by increasing the amount of insulin released by the pancreas and helps regulate the amount of glucose in the blood. It provides better post-meal blood sugar control and reduces the risk of diabetes-related complications by maintaining stable glucose levels.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

REPAGLINIDE-0.5MG+VOGLIBOSE-0.3MG

Manufacturer/Marketer :

Nester Lifescience Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Repaone V-0.5/0.3 Tablet 10's

Repaone V-0.5/0.3 Tablet 10's is a prescription medicine used to manage blood sugar levels in adults with type 2 diabetes. It mainly helps control the rise in blood sugar that occurs after meals. Your doctor may prescribe this combination when diet, exercise, or treatment with a single diabetes medicine does not provide enough blood sugar control.

Take Repaone V-0.5/0.3 Tablet 10's exactly as prescribed, usually shortly before your main meals. If you skip a meal, skip the dose for that meal to reduce the risk of low blood sugar. Following a balanced diet, staying physically active, and checking your blood sugar as advised are also important parts of managing diabetes.

Some people may experience low blood sugar, gas, bloating, diarrhoea, or stomach discomfort. Consult your doctor right away if you develop severe or persistent stomach pain, repeated vomiting, yellowing of the skin or eyes, or symptoms of severe low blood sugar, such as confusion, extreme dizziness, seizures, or loss of consciousness.

Before starting Repaone V-0.5/0.3 Tablet 10's, tell your doctor if you have liver or kidney problems, digestive or bowel conditions, or a history of frequent low blood sugar. Do not take this medicine if you have type 1 diabetes or diabetic ketoacidosis. Your doctor will review your health and current medicines to determine whether this treatment is suitable for you.

Repaone V-0.5/0.3 Tablet 10's may interact with alcohol and certain medicines, including other diabetes medicines. These interactions may affect your blood sugar levels or increase the risk of side effects. If you are pregnant, planning a pregnancy, breastfeeding, or an older adult, consult your doctor before starting treatment.

Uses of Repaone V-0.5/0.3 Tablet 10's

Your doctor may prescribe Repaone V-0.5/0.3 Tablet 10's to manage the following condition: 

  • Type 2 Diabetes Mellitus: Repaone V-0.5/0.3 Tablet 10's helps lower high blood sugar levels, specifically targeting and controlling the sharp sugar spikes that happen immediately after meals.

Key Benefits

When used alongside a balanced diet, regular physical activity, and other parts of your diabetes care plan, Repaone V-0.5/0.3 Tablet 10's helps control post-meal blood sugar levels. The main benefits are:

  • Controls blood sugar after meals: Helps reduce sharp rises in blood sugar after eating.
  • Provides complementary blood sugar control: Combines two medicines that work in different ways to manage post-meal blood sugar levels.
  • Supports long-term diabetes management: Keeping blood sugar within the recommended range may help reduce the risk of diabetes-related complications affecting the nerves, kidneys, eyes, and other parts of the body.
  • Supports steadier blood sugar levels: Better control of post-meal blood sugar may help reduce symptoms related to high blood sugar, such as increased thirst, frequent urination, and tiredness.
Side effects of Repaone V-0.5/0.3 Tablet
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

Directions for Use

  • Repaone V-0.5/0.3 Tablet 10's should be taken at least 30 minutes before a meal.
  • It is usually taken once daily at the same time each day or as prescribed by your doctor.
  • Swallow Repaone V-0.5/0.3 Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Repaone V-0.5/0.3 Tablet 10's Works

Repaone V-0.5/0.3 Tablet 10's contains voglibose and repaglinide, which work in different but complementary ways to control the rise in blood sugar after meals. Voglibose works in the intestine by blocking enzymes called alpha-glucosidases. These enzymes help break down complex carbohydrates from food into simple sugars. By slowing this process, voglibose delays the absorption of sugar into the bloodstream and helps reduce a rapid rise in blood sugar after eating. Repaglinide works by helping the pancreas release insulin around mealtimes. Insulin helps move sugar from the blood into the body’s cells, where it can be used for energy. Together, voglibose and repaglinide help control post-meal blood sugar levels.
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Alcohol

Unsafe

Limit alcohol while taking this medication because it can increase your risk of developing low blood sugar and a high ketone level.

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Pregnancy

Caution

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

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Breast Feeding

Consult your doctor

Please consult your doctor if you have any concerns regarding this; your doctor will decide whether the Repaone V-0.5/0.3 Tablet 10's can be given to breastfeeding mothers or not.

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Driving

Caution

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity requiring alertness or clear vision until you can safely perform such activities.

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Liver

Caution

Repaone V-0.5/0.3 Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. Inform your doctor if you have a history of liver impairment/disorder.

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Kidney

Caution

Repaone V-0.5/0.3 Tablet 10's to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal function. Repaone V-0.5/0.3 Tablet 10's is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Repaone V-0.5/0.3 Tablet 10's. Please consult the doctor before taking this medicine. Your doctor will weigh the benefits and potential risks before prescribing them.

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Children

Unsafe

The safety and efficacy of Repaone V-0.5/0.3 Tablet 10's in children have not been established. Please consult the doctor if you have any doubts or concerns regarding this.

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Heart

Caution

Please inform your doctor if you have a history of heart disease before taking Repaone V-0.5/0.3 Tablet 10's. Your doctor will prescribe it only if the potential benefits outweigh the possible risks.

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Geriatrics

Caution

Repaone V-0.5/0.3 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Repaone V-0.5/0.3 Tablet 10's in geriatrics, please consult your doctor.

What if I have taken an overdose of Repaone V-0.5/0.3 Tablet 10's

Taking too much of this medicine can cause severe low blood sugar (hypoglycaemia). If you suspect an overdose and experience symptoms like confusion, severe shakiness, sweating, or fainting, seek emergency medical care immediately.

Diet & Lifestyle Advise

  • Eat your meals at regular, consistent times every day to help this medicine work safely and prevent sudden drops in blood sugar.
    Always carry a fast-acting sugar source with you, such as fruit juice, raisins, glucose tablets, or hard candy, to treat sudden low blood sugar.
  • Incorporate regular, moderate physical activity like walking into your daily routine, as exercise helps your body use blood sugar more effectively.
  • Monitor your blood sugar levels regularly as advised by your doctor to track how well your treatment is working.
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How Soon It Starts Working

The time required for Repaone V-0.5/0.3 Tablet 10's to start to work: Repaone V-0.5/0.3 Tablet 10's shows its action within 15 to 30 minutes of administration.

The time for which the effects of Repaone V-0.5/0.3 Tablet 10's last: Repaone V-0.5/0.3 Tablet 10's effect lasts for 4 to 6 hours.

What if you forget to take Repaone V-0.5/0.3 Tablet 10's

If you remember your missed dose right before your meal, take it then. If you have already finished your meal, skip the missed dose and take your next dose before your next scheduled meal. Do not take a double dose to make up for a missed one.

Storage

•Store Repaone V-0.5/0.3 Tablet 10's tablets at room temperature, ideally between 15°C and 30°C, in a dry place.

Drug Warnings

  • Do not skip meals: Take Repaone V-0.5/0.3 Tablet 10's shortly before a meal. If you skip a meal, skip the dose for that meal to reduce the risk of low blood sugar.
  • Know the signs of low blood sugar: Watch for sweating, shakiness, hunger, dizziness, weakness, or confusion. Make sure people close to you know these signs and how to help in an emergency.
  • Carry a quick source of sugar: Keep glucose tablets, glucose gel, fruit juice, or hard candy with you in case your blood sugar drops too low.
  • Monitor your blood sugar: Check your blood sugar as advised and keep a record of your readings to share with your doctor during follow-up visits.
  • Check the packaging: Make sure the blister strip is intact and check the expiry date before use. Do not take tablets that are expired or look different from usual.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Repaone V-0.5/0.3 Tablet 10's and require closer monitoring or dose adjustments:

  • Other diabetes medicines: Insulin and medicines such as sulfonylureas may increase the risk of low blood sugar when taken with Repaone V-0.5/0.3 Tablet 10's. Metformin may be used as part of a diabetes treatment plan, but your doctor will decide whether the combination is suitable for you.
  • Beta-blockers: Medicines such as propranolol or metoprolol may make some warning signs of low blood sugar, such as a fast heartbeat, less noticeable.
  • Certain pain relievers: Some medicines, including aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, may affect blood sugar control or increase the risk of low blood sugar. Use them only as advised by your doctor.
  • Steroids, diuretics, and thyroid medicines: These medicines may raise blood sugar levels and reduce the blood-sugar-lowering effect of Repaone V-0.5/0.3 Tablet 10's. Your doctor may monitor your blood sugar more closely.
Repaglinide + VogliboseMoxifloxacin
Severe
Repaglinide + VogliboseCinoxacin
Severe

Drug-Drug Interactions

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Repaglinide + VogliboseMoxifloxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Moxifloxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Moxifloxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseCinoxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Cinoxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Cinoxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseNalidixic acid
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Nalidixic acid with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Nalidixic acid with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseGemifloxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Gemifloxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Gemifloxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseCiprofloxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Ciprofloxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Ciprofloxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseEnoxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Enoxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Enoxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseGrepafloxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Grepafloxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Grepafloxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseOfloxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Ofloxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Ofloxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseClopidogrel
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Clopidogrel with Repaglinide and Voglibose can lead to decrease in blood sugars.

How to manage the interaction:
Although taking clopidogrel with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, or sweating, consult a doctor. Do not discontinue any medication without consulting a doctor.
Repaglinide + VogliboseNorfloxacin
Severe
How does the drug interact with Repaone V-0.5/0.3 Tablet:
Co-administration of Norfloxacin with Repaglinide and Voglibose can lead to increase or decrease in blood sugars.

How to manage the interaction:
Although taking Norfloxacin with Repaglinide and Voglibose may result in interaction, it can be taken if prescribed by a doctor. However, if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, sweating, increased thirst or increased urination, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Certain drinks may affect blood sugar control during treatment.

  • Alcohol: Alcohol may increase the risk of low blood sugar or make blood sugar levels more difficult to control. Limit or avoid alcohol as advised by your doctor.
REPAGLINIDE-0.5MG+VOGLIBOSE-0.3MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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REPAGLINIDE-0.5MG+VOGLIBOSE-0.3MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consumption of grape fruit or grape juice while on the treatment with Repaglinide and Voglibose can increase the blood levels of Repaglinide and Voglibose which can cause headache, dizziness, drowsiness, nervousness, weakness, shaking of hands or legs, nausea, hunger, or sweating. Avoid or limit consumption of grape fruit or grape juice while on the treatment with Repaglinide and Voglibose.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Repaone V-0.5/0.3 Tablet 10's is primarily used to treat Type 2 diabetes. It prevents the rise of blood sugar levels after a meal.
Repaone V-0.5/0.3 Tablet 10's is composed of two medicines, namely Repaglinide and voglibose. Repaglinide increases the amount of insulin released by the pancreas by stimulating the pancreas to release insulin into the body, and helps regulate the amount of glucose (sugar) in the blood. Voglibose helps control the amount of glucose (sugars) in the blood by inhibiting the intestinal enzyme (alpha-glucosidase) and delaying the digestion and absorption of carbohydrates in the intestine. Altogether, they prevent blood sugar from rising very high after meals.
If you have symptoms like increased hunger, thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact the doctor, as it can be a condition of type 2 diabetes.
No. Repaone V-0.5/0.3 Tablet 10's is only prescribed to treat type 2 diabetes, also called non-insulin-dependent diabetes.
Repaone V-0.5/0.3 Tablet 10's should be avoided in patients allergic to any of the components or excipients of this medicine. Make sure to inform your healthcare professional if you are pregnant or breastfeeding.
Do not take Repaone V-0.5/0.3 Tablet 10's if you are pregnant unless prescribed by the doctor. Your doctor will prescribe Repaone V-0.5/0.3 Tablet 10's only if the benefits outweigh the risks.
Please do not stop taking Repaone V-0.5/0.3 Tablet 10's without consulting your doctor on your own, as it may cause an increase in blood glucose levels. Continue taking Repaone V-0.5/0.3 Tablet 10's for as long as your doctor prescribes it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Repaone V-0.5/0.3 Tablet 10's.
Swallow the medicine as a whole with water; do not crush, break or chew it.
Repaone V-0.5/0.3 Tablet 10's is composed of two medicines, namely Repaglinide and voglibose.
The dose of Repaone V-0.5/0.3 Tablet 10's depends on your medical condition, age, and response to treatment. Your doctor will determine the best dose for you.
Common side effects of Repaone V-0.5/0.3 Tablet 10's may include hypoglycaemia, allergy, stomach pain, diarrhoea, and nausea. These side effects may occur in some individuals but not everyone. Most side effects are temporary and don't require medical attention, but consult your doctor if they persist.
Before starting Repaone V-0.5/0.3 Tablet 10's, discuss your medical history, allergies, current medications, and concerns with your physician.
No. If you skip a meal, skip the dose for that meal. Taking Repaone V-0.5/0.3 Tablet 10's without eating may increase the risk of low blood sugar. Follow your doctor’s advice if your meal schedule changes frequently.
Repaone V-0.5/0.3 Tablet 10's is taken shortly before meals to help control the rise in blood sugar after eating. Your blood sugar readings may begin to improve after starting treatment, but the response varies between individuals. Your doctor may also check your HbA1c, usually about every 3 months, to assess long-term blood sugar control.
If you feel shaky, sweaty, hungry, dizzy, weak, or confused, check your blood sugar if possible and take a fast-acting source of sugar, such as glucose tablets, glucose gel, or fruit juice. Check your blood sugar again after 15 minutes and repeat treatment if it remains low. Seek urgent medical help if you have seizures, lose consciousness, or cannot safely eat or drink.
Alcohol can make blood sugar levels more difficult to control and may increase the risk of low blood sugar. Limit or avoid alcohol during treatment, particularly if you have liver problems or frequently experience low blood sugar.
Repaglinide may cause modest weight gain in some people. Following your recommended diet, staying physically active, and monitoring your weight may help manage weight changes. Inform your doctor if you experience rapid or significant weight gain.
Tell your doctor if you have kidney problems before taking Repaone V-0.5/0.3 Tablet 10's. Your doctor will assess your kidney function, blood sugar levels, other medicines, and overall health to determine whether this treatment is suitable for you.

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Country of origin

India

Manufacturer/Marketer address

SF-22, Rajratna Complex, Opp. Navrangpura Municipal School, Navrangpura, Ahmedabad-380009, Gujarat
Other Info - REP0398
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