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Tofadoz-11 XR Tablet 10's
Tofadoz-11 XR Tablet 10's

Tofadoz 11 XR Tablet is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It contains Tofacitinib which works by lowering inflammation and symptoms associated with arthritis. In some cases, this medicine may cause side effects such as diarrhoea, headache, upper respiratory tract infection, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Tofadoz-11 XR Tablet
  • Practice good hygiene by washing hands frequently when touching any wounds.
  • Apply creams or lotions to the dry skin and moisturize it.
  • Wear the proper clothing and footwear when working outside.
  • Cover the wounds with bandage and change it daily.
  • Avoid baths at swimming pools, lakes and rivers.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Drink a lot of water to control diarrhoea and prevent dehydration.
  • Avoid spicy, fatty, or high-fiber foods that may irritate the colon.
  • Reduce stress through methods such as deep breathing or meditation.
  • Include probiotics or supplements containing live bacteria to maintain the health of the gut.
  • Quit smoking since smoking makes colitis symptoms worse.
  • See your doctor right away if you experience extreme inflammation, bleeding stools, or abdominal pain.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • To promote overall health, drink plenty of water and consume hydrating foods like watermelon and leafy greens.
  • Support gut health with probiotic-rich foods such as yoghurt and sauerkraut.
  • Eat antioxidant-rich foods like berries and green tea, while limiting sugary drinks, alcohol, and processed foods.
  • Additionally, reduce stress through relaxation techniques like deep breathing and meditation.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug-Drug Interactions

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TofacitinibBoceprevir
Severe
TofacitinibFluorouracil
Severe

Drug-Drug Interactions

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TofacitinibBoceprevir
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking Tofadoz-11 XR Tablet with Boceprevir may increases the blood levels of Tofadoz-11 XR Tablet which increases risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Tofadoz-11 XR Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
TofacitinibFluorouracil
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Using Tofadoz-11 XR Tablet together with fluorouracil may increase the risk of serious infections.

How to manage the interaction:
Although there is a interaction between Tofadoz-11 XR Tablet and fluorouracil but can be taken if advised by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TofacitinibPrimidone
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking Tofadoz-11 XR Tablet with Primidone may reduce the blood levels and effects of Tofadoz-11 XR Tablet.

How to manage the interaction:
Although there is an interaction between Primidone and Tofadoz-11 XR Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TofacitinibTacrolimus
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking tacrolimus together with Tofadoz-11 XR Tablet may increase the risk of serious infections.

How to manage the interaction:
Although taking tacrolimus and Tofadoz-11 XR Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TofacitinibItraconazole
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking Itraconazole with Tofadoz-11 XR Tablet may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Tofadoz-11 XR Tablet and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
TofacitinibTopotecan
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking Tofadoz-11 XR Tablet with Topotecan may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofadoz-11 XR Tablet and Topotecan, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibCarfilzomib
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking Carfilzomib with Tofadoz-11 XR Tablet may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Tofadoz-11 XR Tablet with Carfilzomib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibVincristine
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Taking Tofadoz-11 XR Tablet with Vincristine may increase the risk of infection.

How to manage the interaction:
Co-administration of Vincristine with Tofadoz-11 XR Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
TofacitinibBudesonide
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
Using Tofadoz-11 XR Tablet together with budesonide may increase the risk of serious infections.

How to manage the interaction:
Co-administration of budesonide along with Tofadoz-11 XR Tablet can lead to an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
TofacitinibVoriconazole
Severe
How does the drug interact with Tofadoz-11 XR Tablet:
When Tofadoz-11 XR Tablet is taken with Voriconazole may increase the risk of side effects.

How to manage the interaction:
Although taking Voriconazole and Tofadoz-11 XR Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, fever, shortness of breath, and pain or burning during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TOFACITINIB-11MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consuming grapefruit products while taking Tofadoz-11 XR Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofadoz-11 XR Tablet, as it can lead to an interaction.

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