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సంఘటన :
TOFACITINIB-5MG
తయారీదారు/మార్కెటర్ :
Pfizer Ltd
వినియోగ రకం :
నోటి ద్వారా
రిటర్న్ పాలసీ :
తిరిగి ఇవ్వబడదు
ఇప్పటి నుండి గడువు ముగుస్తుంది :
Jan-27
Have a query?
Drug-Drug Interactions
Severe
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Ifosfamide with Tofashine 5 mg Tablet may increase the risk of serious infection.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Ifosfamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Taking Ifosfamide with Tofashine 5 mg Tablet may increase the risk of serious infection.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Ifosfamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on your condition. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Oxaliplatin may increase the risk of infection.
How to manage the interaction:
Although taking Oxaliplatin and Tofashine 5 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
Taking Tofashine 5 mg Tablet with Oxaliplatin may increase the risk of infection.
How to manage the interaction:
Although taking Oxaliplatin and Tofashine 5 mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Tofashine 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
Taking Tofashine 5 mg Tablet with Dactinomycin may increase the risk of serious infection.
How to manage the interaction:
Taking Dactinomycin with Tofashine 5 mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any complications, infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning when you pee, make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
TofacitinibTelithromycin
Severe
How does the drug interact with Tofashine 5 mg Tablet:
When Tofashine 5 mg Tablet is taken with Telithromycin, it can slow down the way the body breaks down Tofashine 5 mg Tablet.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
When Tofashine 5 mg Tablet is taken with Telithromycin, it can slow down the way the body breaks down Tofashine 5 mg Tablet.
How to manage the interaction:
Taking Tofashine 5 mg Tablet with Telithromycin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Co-administration of Tofashine 5 mg Tablet and Prednisolone can increase the risk of serious infections, diverticular disease (development of small bulges in the lining of the intestine), or gastrointestinal bleeding or perforation.
How to manage the interaction:
Although taking Tofashine 5 mg Tablet and Prednisolone together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in the coughing fluid, weight loss, red or inflamed skin, body sores, pain or burning when urinating, severe abdominal pain, fever, nausea, or vomiting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Tofashine 5 mg Tablet and Prednisolone can increase the risk of serious infections, diverticular disease (development of small bulges in the lining of the intestine), or gastrointestinal bleeding or perforation.
How to manage the interaction:
Although taking Tofashine 5 mg Tablet and Prednisolone together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in the coughing fluid, weight loss, red or inflamed skin, body sores, pain or burning when urinating, severe abdominal pain, fever, nausea, or vomiting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TofacitinibBoceprevir
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Boceprevir may increases the blood levels of Tofashine 5 mg Tablet which increases risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Tofashine 5 mg Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tofashine 5 mg Tablet with Boceprevir may increases the blood levels of Tofashine 5 mg Tablet which increases risk of side effects.
How to manage the interaction:
There may be a possibility of interaction between Tofashine 5 mg Tablet and Boceprevir, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, fainting, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Vincristine may increase the risk of infection.
How to manage the interaction:
Co-administration of Vincristine with Tofashine 5 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Taking Tofashine 5 mg Tablet with Vincristine may increase the risk of infection.
How to manage the interaction:
Co-administration of Vincristine with Tofashine 5 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking azacitidine with Tofashine 5 mg Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Azacitidine and Tofashine 5 mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
Taking azacitidine with Tofashine 5 mg Tablet can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between Azacitidine and Tofashine 5 mg Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Co-administration of Tofashine 5 mg Tablet with Capecitabine may increase the risk of serious and potential infections.
How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofashine 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
Co-administration of Tofashine 5 mg Tablet with Capecitabine may increase the risk of serious and potential infections.
How to manage the interaction:
Although there is an interaction, Capecitabine can be taken with Tofashine 5 mg Tablet if prescribed by the doctor. Consult the prescriber if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue the medication without consulting a doctor.
Severe
How does the drug interact with Tofashine 5 mg Tablet:
Taking Tofashine 5 mg Tablet with Temsirolimus may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Taking Tofashine 5 mg Tablet with Temsirolimus may increase the risk of infection.
How to manage the interaction:
Although there is a possible interaction between Tofashine 5 mg Tablet and Temsirolimus, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting your doctor.
Drug-Food Interactions
TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Drug-Food Interactions
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TOFACITINIB-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofashine 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofashine 5 mg Tablet, as it can lead to an interaction.
Grapefruit, Grapefruit Juice
How to manage the interaction:
Consuming grapefruit products while taking Tofashine 5 mg Tablet can increase the risk of side effects. Avoid consuming grapefruit products while being treated with Tofashine 5 mg Tablet, as it can lead to an interaction.
మద్యం
జాగ్రత్త
ఆల్కహాల్ Tofashine 5 mg Tablet 10'sతో సంకర్షణ చెందుతుందో లేదో తెలియదు, కాబట్టి దయచేసి వైద్యుడిని సంప్రదించండి.
గర్భం
అసురక్షితం
గర్భధారణ సమయంలో Tofashine 5 mg Tablet 10's తీసుకోకూడదు. మీరు గర్భం దాల్చే అవకాశం ఉన్న స్త్రీ అయితే, Tofashine 5 mg Tablet 10'sతో చికిత్స సమయంలో మరియు ఆపివేసిన 4 వారాల తర్వాత ప్రభావవంతమైన గర్భనిరోధకతను ఉపయోగించండి.
తల్లిపాలు ఇవ్వడం
అసురక్షితం
Tofashine 5 mg Tablet 10's తీసుకుంటున్నప్పుడు తల్లిపాలు ఇవ్వడం మానుకోండి. మీకు ఏవైనా సందేహాలు ఉంటే దయచేసి వైద్యుడిని సంప్రదించండి.
డ్రైవింగ్
సురక్షితం
సాధారణంగా Tofashine 5 mg Tablet 10's మీరు డ్రైవ్ చేసే సామర్థ్యాన్ని ప్రభావితం చేయదు. అయితే, మీరు అప్రమత్తంగా ఉంటే మాత్రమే డ్రైవ్ చేయండి లేదా యంత్రాలను నడపండి.
కాలేయం
జాగ్రత్త
కాలేయ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కాలేయ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి. తీవ్రమైన కాలేయ సమస్యలు ఉన్న రోగులకు Tofashine 5 mg Tablet 10's సిఫార్సు చేయబడలేదు.
కిడ్నీ
జాగ్రత్త
కిడ్నీ బలహీనత ఉన్న రోగులలో మోతాదు సర్దుబాటు అవసరం కావచ్చు. మీకు కిడ్నీ బలహీనత లేదా దీనికి సంబంధించి ఏవైనా సందేహాలు ఉంటే దయచేసి మీ వైద్యుడిని సంప్రదించండి.
పిల్లలు
అసురక్షితం
భద్రత మరియు ప్రభావం నిర్ధారించబడనందున 18 సంవత్సరాల కంటే తక్కువ వయస్సు ఉన్న పిల్లలకు Tofashine 5 mg Tablet 10's సిఫార్సు చేయబడలేదు.
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