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Zuprinor 10 Transdermal Patch is primarily used to treat pain. It contains 'Buprenorphine', an opioid partial agonist-antagonist. It works by blocking a chemical messenger in the brain that is responsible for causing pain. This provides pain relief by acting on specific receptors in the brain. Common side effects of Zuprinor 10 Transdermal Patch are drowsiness, dry mouth, vomiting, blurred vision, constipation, application site reactions, dizziness, or tiredness.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical
How does the drug interact with Zuprinor 10 Transdermal Patch:
Using alvimopan together with Zuprinor 10 Transdermal Patch can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Zuprinor 10 Transdermal Patch is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
Taking Ziprasidone with Zuprinor 10 Transdermal Patch can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Zuprinor 10 Transdermal Patch is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
When Zuprinor 10 Transdermal Patch is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
There's an interaction between Zuprinor 10 Transdermal Patch alongside Selegiline that can result in an interaction but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
Taking Zuprinor 10 Transdermal Patch with bupropion may raise the chance of seizures, which can happen with either medicine.

How to manage the interaction:
Co- administration of Zuprinor 10 Transdermal Patch along with bupropion can lead to an interaction, it can be taken if recommended by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these drugs effect you. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
When Zuprinor 10 Transdermal Patch is used with Clonazepam, it may lead to significant adverse effects such as respiratory difficulties.

How to manage the interaction:
Co-administration of Zuprinor 10 Transdermal Patch alongside Clonazepam can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you know how these drugs affect you. Do not discontinue any medications without consulting a doctor.
BuprenorphineMephenytoin
Severe
How does the drug interact with Zuprinor 10 Transdermal Patch:
Using Zuprinor 10 Transdermal Patch together with Mephenytoin can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Mephenytoin and Zuprinor 10 Transdermal Patch, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on your health and be aware of any changes. If you experience tiredness or having trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
Co-administration of Zuprinor 10 Transdermal Patch with divalproex may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Zuprinor 10 Transdermal Patch with Divalproex can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
Coadministration of phenytoin and Zuprinor 10 Transdermal Patch may reduce the blood levels of Zuprinor 10 Transdermal Patch.

How to manage the interaction:
Although taking Zuprinor 10 Transdermal Patch and phenytoin together can result in an interaction, it can be taken if a doctor has advised it. Ensure that you are taking these drugs precisely as directed. consult the doctor, if you experience restlessness, irritability, anxiety, depression, pupil dilation, tremors, rapid heartbeat, body aches, involuntary shaking and kicking, abdominal pain, decreased hunger, nausea, vomiting, diarrhea, and weight loss. Avoid tasks demanding mental focus, such as handling dangerous machinery or operating a vehicle. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Zuprinor 10 Transdermal Patch:
When Zuprinor 10 Transdermal Patch is used with topiramate, it may lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of Zuprinor 10 Transdermal Patch alongside topiramate can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Consult a doctor if you have any questions or concerns. Do not discontinue any medications without consulting a doctor.
BuprenorphineParaldehyde
Severe
How does the drug interact with Zuprinor 10 Transdermal Patch:
Using Zuprinor 10 Transdermal Patch together with Paraldehyde can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Paraldehyde and Zuprinor 10 Transdermal Patch together can cause an interaction, it can be taken if a doctor has suggested it. Doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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