Why Do False Positives Occur?
Although false positives are uncommon, several legitimate biological and technical factors can contribute to them.
1. Chemical Pregnancy (Very Early Pregnancy Loss)
A chemical pregnancy is one of the most frequent causes of false positives. It happens when:
1. Fertilisation occurs
2. hCG begins to rise
3. The pregnancy does not progress beyond the earliest stage
Because the hormone was produced briefly, the test turns positive. By the time you test again, hCG may have dropped, resulting in a negative result.
Possible reasons include:
1. Chromosomal abnormalities
2. Implantation failure
3. Hormonal imbalance
Chemical pregnancies are very early losses and are not a reflection of future fertility issues.
2. Evaporation Lines
If a test is read outside the recommended time window, an evaporation line may appear. These faint, often colourless marks may resemble a positive result.
Characteristics of evaporation lines:
1. Usually lacks colour
2. Appear after the urine dries
3. Often thinner than the control line
This is why reading the test at the exact time specified in the instructions (usually 3–5 minutes) is crucial.
3. Fertility Treatments Containing hCG
Women undergoing fertility treatment may be prescribed hCG injections to trigger ovulation. These medications can remain in the body for up to two weeks, leading to false positives.
If you have received such treatment, your doctor will advise you when to take a home test.
4. Certain Medical Conditions
Some medical conditions cause elevated hCG levels or substances similar to hCG, which can affect the test.
These may include:
1. Ovarian cysts
2. Certain tumours
3. Pituitary hCG production (uncommon in older women)
4. Disorders of the reproductive organs
Although rare, these health conditions can influence test results and require medical assessment.
5. Medications That Can Influence Results
Most medicines do not affect pregnancy test results. However, a few drugs can potentially cause a false positive.
These include:
1. hCG-containing fertility injections
2. Certain antipsychotic medicines (in rare cases)
3. Some anti-seizure medications
If you are on fertility-related medication, always check the timing of your test.
6. Recent Pregnancy, Miscarriage, or Abortion
After childbirth, miscarriage, or medical abortion, hCG may remain in the body for days to weeks. During this time, a pregnancy test may show a positive result even though the pregnancy is not ongoing.
7. Faulty or Expired Test Kits
Using an expired or damaged test kit can lead to inaccurate results.
Common issues include:
1. Antibodies lose sensitivity over time
2. Exposure to heat or moisture
3. Damaged packaging
4. Rare manufacturing defects
Always check the expiry date and ensure the packaging is intact.
8. User Error or Incorrect Technique
Incorrect use is surprisingly common and can lead to false readings.
Examples include:
1. Leaving the test strip in urine for too long
2. Allowing urine to spill onto the result window
3. Not placing the test on a flat surface
4. Reading the result too late
5. Testing without tracking cycle timing
Following the instructions carefully is essential for accuracy.