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Aldactone 100 Tablet 15's
Aldactone 100 Tablet 15's
Aldactone 100 Tablet 15's
Aldactone 100 Tablet 15's
Aldactone 100 Tablet 15's
Aldactone 100 Tablet 15's

Aldactone 100 Tablet is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. It contains Spironolactone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future. In some cases, this medication may cause common side effects, including low blood pressure, dehydration, drowsiness, dizziness, high potassium levels, low sodium levels, elevated creatinine levels, headaches, breast enlargement in males, and absence of menstrual periods in females. Before taking this medication, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medicines you are taking and any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Health Queries

Is Aldactone 100 Tablet an anti-androgen?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

Yes, Aldactone 100 Tablet (Spironolactone) has anti-androgenic effects. It is primarily a potassium-sparing diuretic used to treat high blood pressure (hypertension) and fluid retention (oedema), but it can also block the action of male hormones (androgens). Because of this, it is sometimes used off-label for conditions such as acne, excess hair growth (hirsutism), and hormonal imbalances. Always consult a doctor before using it for these purposes to ensure it is safe and appropriate for you.

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Side effects of Aldactone 100 Tablet
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Practice good hygiene by washing the vaginal area with water and mild soap.
  • Wear breathable cotton underwear and avoid scented products.
  • Check vaginal secretion changes, including colour, texture, amount, and smell.
  • Be aware of potential causes like infection or pregnancy.
  • Consult a doctor if secretions are unusual, or smelly with pain.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
  • If you experience a lack of energy due to liver conditions, consult your doctor to determine the underlying cause and further management.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine instead drink plenty of water.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug-Drug Interactions

verifiedApollotooltip
SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with Aldactone 100 Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Aldactone 100 Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with Aldactone 100 Tablet:
Coadministration of Amiloride with Aldactone 100 Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Aldactone 100 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactoneValsartan
Severe
How does the drug interact with Aldactone 100 Tablet:
Using Aldactone 100 Tablet together with valsartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aldactone 100 Tablet and valsartan together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting a doctor.
SpironolactoneMorphine
Severe
How does the drug interact with Aldactone 100 Tablet:
Taking Aldactone 100 Tablet with morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Aldactone 100 Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination make sure to contact a doctor. Do not stop using any medications without consulting a doctor.
SpironolactoneCiclosporin
Severe
How does the drug interact with Aldactone 100 Tablet:
Taking Aldactone 100 Tablet with ciclosporin may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aldactone 100 Tablet and ciclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience slow, fast, or uneven heartbeat, rapid breathing, numbness or tingly feeling, and muscle pain or weakness. Do not stop using any medications without consulting a doctor.
SpironolactonePotassium citrate
Severe
How does the drug interact with Aldactone 100 Tablet:
Taking Aldactone 100 Tablet with potassium citrate may increase potassium levels in the blood which can lead to kidney problems and abnormal heart rhythm.

How to manage the interaction:
Although taking Aldactone 100 Tablet and potassium citrate together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
SpironolactoneCaptopril
Severe
How does the drug interact with Aldactone 100 Tablet:
Combining Aldactone 100 Tablet with Captopril may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Taking Captopril with Aldactone 100 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advise.
SpironolactonePerindopril
Severe
How does the drug interact with Aldactone 100 Tablet:
Using perindopril together with Aldactone 100 Tablet may cause hyperkalemia (high potassium level in blood).

How to manage the interaction:
Although taking Aldactone 100 Tablet and perindopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop using any medications without consulting doctor.
SpironolactoneVenetoclax
Severe
How does the drug interact with Aldactone 100 Tablet:
Taking Aldactone 100 Tablet with venetoclax may significantly increase the blood levels and side effects of venetoclax.

How to manage the interaction:
Although taking Aldactone 100 Tablet and azilsartan medoxomil together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, diarrhea, fatigue, anemia (low numbers of blood cells), bleeding problems, and infections. Do not stop using any medications without consulting doctor.
SpironolactoneRamipril
Severe
How does the drug interact with Aldactone 100 Tablet:
Using ramipril together with Aldactone 100 Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking Aldactone 100 Tablet and captopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 21, 2025 | 11:22 AM IST

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