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Aldactone Tablet 15's
Aldactone Tablet 15's
Aldactone Tablet 15's

Aldactone Tablet is used to treat oedema (fluid overload) associated with hepatic cirrhosis (chronic liver damage), congestive heart failure, and nephrotic syndrome (a kidney condition characterized by excessive protein loss in the urine). It is also effective in managing hypertension (high blood pressure), hypokalaemia (low blood potassium levels), primary hyperaldosteronism (a condition with excessive aldosterone hormone), and heart failure. It contains Spironolactone, which works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney, or lung disease. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack, stroke, or angina (chest pain) in the future. In some cases, this medication may cause common side effects, including low blood pressure, dehydration, drowsiness, dizziness, high potassium levels, low sodium levels, elevated creatinine levels, headaches, breast enlargement in males, and absence of menstrual periods in females. Before taking this medication, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medicines you are taking and any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Health Queries

I have had left knee pain for many years, which used to worsen during periods. I have undergone uterus removal (hysterectomy), but my tubes are intact. I also have high blood pressure and take Aldactone 25 mg. My doctor prescribed alendronic acid 70 mg weekly along with supplements. How long can I safely take alendronic acid? Also, since I have poor dental health and exposed roots, what precautions should I take if I need a tooth extraction in the future?

Dr G Reddy

Dr G Reddy

M Pharmacy (Pharmaceutics)

Alendronic acid is commonly used for bone strengthening and is usually taken for 3-5 years, after which your doctor may reassess and sometimes give a gap depending on your bone health and risk. It is generally safe when taken as prescribed, but regular follow-up is important. A key precaution is dental care, as this medicine can rarely affect jaw healing (called Osteonecrosis of the Jaw). Before any tooth extraction or major dental procedure, inform both your dentist and doctor that you are taking this medicine; they may plan treatment carefully or advise timing adjustments. Maintain good oral hygiene and get routine dental check-ups to reduce risks.

I sometimes get sudden increases in my blood pressure. Should I be concerned?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

Sudden increases in blood pressure can occur due to stress, anxiety, poor sleep, excess salt intake, or missed medicines. Occasional rises may not be serious, but frequent spikes need medical attention. Monitor your blood pressure regularly and consult your doctor to adjust treatment if needed.

I am a patient with hypertension. What precautions should I follow to keep my blood pressure under control?

Dr S Aneela

Dr S Aneela

M. Pharm (Pharmacology)., PhD

Control your blood pressure by taking your medicines regularly, reducing salt intake, and eating a healthy diet. Exercise regularly, maintain a healthy weight, and avoid stress, smoking, and excess alcohol. Monitor your blood pressure regularly and consult your doctor for proper follow-up.

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Side effects of Aldactone Tablet
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Practice good hygiene by washing the vaginal area with water and mild soap.
  • Wear breathable cotton underwear and avoid scented products.
  • Check vaginal secretion changes, including colour, texture, amount, and smell.
  • Be aware of potential causes like infection or pregnancy.
  • Consult a doctor if secretions are unusual, or smelly with pain.
  • Vaginal bleeding can be abnormal if it is not related to menstruation, and needs immediate attention and cannot be ignored.
  • Get a physical examination and follow your doctor's instructions to get relief from bleeding.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Prefer practicing yoga and meditation to reduce stress and anxiety, as it can worsen vaginal bleeding.
  • Take a balanced diet and manage your weight.
  • Eat a healthy balanced diet.
  • Reduce stress with relaxation techniques such as yoga or meditation.
  • Keep track of your menstrual cycle any irregularities.
  • Have regular check ups to exclude other health problems.
  • Exercise but do not exercise to the extent of overheating.
  • Hydrate well, eat well (particularly iron and vitamins).
  • If you experience a lack of energy due to liver conditions, consult your doctor to determine the underlying cause and further management.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine instead drink plenty of water.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
SpironolactoneAmiloride
Critical

Drug-Drug Interactions

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SpironolactoneEplerenone
Critical
How does the drug interact with Aldactone Tablet:
Combining Eplerenone with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Aldactone Tablet and eplerenone, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
SpironolactoneAmiloride
Critical
How does the drug interact with Aldactone Tablet:
Coadministration of Amiloride with Aldactone Tablet may increase potassium levels in the blood.

How to manage the interaction:
Taking Amiloride with Aldactone Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctor's advice.
SpironolactonePerindopril
Severe
How does the drug interact with Aldactone Tablet:
Using perindopril together with Aldactone Tablet may cause hyperkalemia (high potassium level in blood).

How to manage the interaction:
Although taking Aldactone Tablet and perindopril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeats. Do not stop using any medications without consulting doctor.
SpironolactoneMorphine
Severe
How does the drug interact with Aldactone Tablet:
Taking Aldactone Tablet with morphine may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Aldactone Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination make sure to contact a doctor. Do not stop using any medications without consulting a doctor.
SpironolactoneTelmisartan
Severe
How does the drug interact with Aldactone Tablet:
Taking Aldactone Tablet with telmisartan may increase potassium levels in the blood.

How to manage the interaction:
Although there is a possible interaction, telmisartan can be taken with Aldactone Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of high potassium such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Maintain adequate fluid intake during treatment with these medications. Do not discontinue the medications without consulting a doctor.
SpironolactoneQuinapril
Severe
How does the drug interact with Aldactone Tablet:
Using quinapril together with Aldactone Tablet may cause hyperkalemia (increase the levels of potassium in your blood).

How to manage the interaction:
Although taking Aldactone Tablet and quinapril together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as weakness, confusion, numbness or tingling, and uneven heartbeat. Do not stop using any medications without consulting doctor.
SpironolactonePazopanib
Severe
How does the drug interact with Aldactone Tablet:
Taking Aldactone Tablet with pazopanib may significantly increase the blood levels of pazopanib. This could increase the risk of severe adverse effects.

How to manage the interaction:
Although taking Aldactone Tablet and pazopanib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, chest pain, pain in your arms, back, neck, or jaw, slurred speech or difficulty speaking, shortness of breath. Do not stop using any medications without consulting doctor.
SpironolactoneLoperamide
Severe
How does the drug interact with Aldactone Tablet:
When taken in combination Aldactone Tablet may significantly raise the loperamide levels in the blood.

How to manage the interaction:
Although taking loperamide with Aldactone Tablet together can result in an interaction, they can be taken if your doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop taking any medication without doctor's advice.
SpironolactoneAzilsartan medoxomil
Severe
How does the drug interact with Aldactone Tablet:
Coadministration of Azilsartan medoxomil with Aldactone Tablet may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aldactone Tablet and Azilsartan medoxomil together can result in an interaction, it can be taken if a doctor has prescribed it. Consult the doctor if you experience vomiting, weakness, confusion, tingling of the hands and feet, or palpitations. Do not stop using any medications without consulting a doctor.
SpironolactoneEprosartan
Severe
How does the drug interact with Aldactone Tablet:
Taking Aldactone Tablet with eprosartan may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aldactone Tablet and eprosartan together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Nov 21, 2025 | 11:22 AM IST

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