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Anbarone Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Anbarone Tablet may interact with anticonvulsants (carbamazepine, phenytoin), antiviral drugs (nelfinavir, ritonavir), a medicine used to treat Cushing’s syndrome (aminoglutethimide), antibiotics (co-trimoxazole, rifampicin, tetracycline), immunosuppressant (ciclosporin).

Drug-Food Interaction: Anbarone Tablet may interact with St. John’s wort (herbal medicine used to treat depression). Also, limit the intake of grapefruit juice with Anbarone Tablet as it may increase the levels of Anbarone Tablet in the blood.  

Drug-Disease Interactions: Avoid taking Anbarone Tablet if you have vaginal bleeding, blood clots, severe itching, porphyria (blood disorder), liver problems, angina (chest pain), or if you ever had a heart attack, jaundice, or pemphigoid gestationis (an itchy rash that develops into blisters). If you have asthma, migraine headaches, epilepsy (fits), kidney or heart problems, inform your doctor before taking Anbarone Tablet .

Drug-Drug Interactions

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How does the drug interact with Anbarone Tablet:
Coadministration of Phenytoin and Anbarone Tablet may decrease the blood levels of Anbarone Tablet, which may make Anbarone Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Anbarone Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Anbarone Tablet:
Coadministration of Acitretin with Anbarone Tablet may interfere with the contraceptive effect of Anbarone Tablet.

How to manage the interaction:
Acitretin and Anbarone Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.
How does the drug interact with Anbarone Tablet:
Coadministration of Anbarone Tablet with Dabrafenib can reduce the metabolism and decrease the levels of Anbarone Tablet in the body.

How to manage the interaction:
Taking Anbarone Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Anbarone Tablet:
Eslicarbazepine may reduce the effects of Anbarone Tablet and its blood levels.

How to manage the interaction:
Although taking Eslicarbazepine and Anbarone Tablet results in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Anbarone Tablet:
Coadministration of Anbarone Tablet and Mycophenolic acid can decrease the levels and effects of Anbarone Tablet.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Anbarone Tablet, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Anbarone Tablet:
Using Felbamate and Anbarone Tablet together can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
There may be a possibility of interaction between Anbarone Tablet and Felbamate, but it can be taken if prescribed by a doctor. If you notice any unusual symptoms like changes in your menstrual cycle, excessive bleeding, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Anbarone Tablet:
Co-administration of Anbarone Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Anbarone Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Anbarone Tablet:
Coadministration of Anbarone Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Anbarone Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Anbarone Tablet:
Coadministration of Anbarone Tablet with Rifabutin can reduce the blood levels and effects of norethindrone.This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Taking Anbarone Tablet with Rifabutin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of abnormal bleeding, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Anbarone Tablet:
Using Etretinate and Anbarone Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Anbarone Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Anbarone Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Anbarone Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Anbarone Tablet dose.

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