ATZ 50 Tablet का उपयोग, फायदे ,साइड इफेक्ट,कीमत in Hindi

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ATZ 50 Tablet is an immunosuppressant primarily used to prevent kidney transplant rejection and manage the symptoms of active rheumatoid arthritis (a condition in which the immune system attacks the joints). It suppresses the overactive immune system by inhibiting the proliferation of certain white blood cells, thereby helping to prevent the body from rejecting newly transplanted organs. It also helps relieve joint pain and inflammation and slows disease progression in patients with rheumatoid arthritis.

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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Side effects of ATZ 50 Tablet

Bone Marrow Suppression

Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
Limit alcohol intake and abstain from smoking to promote general wellbeing.

Low White Blood Cell Count

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Infections

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Have a query?

Drug-Drug Interactions

Drug-Drug Interactions: ATZ 50 Tablet may interact with certain medicines, potentially increasing side effects or altering their effectiveness. Inform your doctor if you are taking any of the following:

Drugs used to treat gout (Allopurinol, Febuxostat)
• Potential effect: May increase the blood levels and effects of Azathioprine.
Immunosuppressants (Cladribine)
• Potential effect: May increase the risk of serious infections and certain cancers (such as skin and lymph gland cancer).
Disease-modifying anti-rheumatic drugs (Adalimumab, Baricitinib, Tofacitinib)
• Potential effect: May increase the risk of serious infections.
Drugs used to treat multiple sclerosis (Fingolimod, Teriflunomide)
• Potential effect: May increase the risk of developing anaemia, bleeding issues, and infections.
Anti-cancer medications (Mercaptopurine)
• Potential effect: May increase the risk of side effects.

Drug-Food Interactions: Avoid consuming alcohol while taking ATZ 50 Tablet , as it may cause increased dizziness.

Drug-Disease Interactions: ATZ 50 Tablet should be avoided or used with caution in people with:

Bone marrow depression (a serious condition in which the bone marrow produces fewer blood cells or platelets)
Serious bacterial, fungal, or viral infections
Kidney dysfunction
Liver disease

AzathioprineFebuxostat

Critical

AzathioprineCladribine

Severe

Drug-Drug Interactions

AzathioprineFebuxostat

Critical

How does the drug interact with ATZ 50 Tablet:
Taking ATZ 50 Tablet and Febuxostat together can increase the blood levels of ATZ 50 Tablet

How to manage the interaction:
Taking ATZ 50 Tablet with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

AzathioprineCladribine

Severe

How does the drug interact with ATZ 50 Tablet:
The use of cladribine with ATZ 50 Tablet can increase the risk of serious infections.

How to manage the interaction:
Although taking ATZ 50 Tablet and Cladribine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience symptoms fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.

AzathioprineAdalimumab

Severe

How does the drug interact with ATZ 50 Tablet:
When ATZ 50 Tablet and Adalimumab are taken together, they may raise the risk of severe infections.

How to manage the interaction:
Although there is a possible interaction between ATZ 50 Tablet and Adalimumab, you can take these medicines together if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.

AzathioprineBaricitinib

Severe

How does the drug interact with ATZ 50 Tablet:
Coadministration of baricitinib and ATZ 50 Tablet can raise the risk of developing harmful infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with ATZ 50 Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

AzathioprineMercaptopurine

Severe

How does the drug interact with ATZ 50 Tablet:
The combined use of ATZ 50 Tablet with Mercaptopurine together can increase the risk of side effects.

How to manage the interaction:
Co-administration of ATZ 50 Tablet with Mercaptopurine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately, if you experience any symptoms such as bruising or bleeding, fever, chills, sore throat, flu symptoms, mouth sores, black urine, severe stomach pain, jaundice (yellowing of the skin or eyes), or severe nausea, vomiting, or diarrhea. Do not stop using any medications without a doctor's advice.

AzathioprineTeriflunomide

Severe

How does the drug interact with ATZ 50 Tablet:
When ATZ 50 Tablet is taken with Teriflunomide, may raise the risk of side effects affecting bone marrow function, resulting in low levels of different types of blood cells. This can increase your chances of developing anemia, bleeding issues, or infections.

How to manage the interaction:
Taking ATZ 50 Tablet with Teriflunomide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience paleness, exhaustion, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, or pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

AzathioprineLeflunomide

Severe

How does the drug interact with ATZ 50 Tablet:
Taking ATZ 50 Tablet with Leflunomide can increase the risk of side effects which may lead to anemia, bleeding problems, or infections.

How to manage the interaction:
Taking Leflunomide with ATZ 50 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, pain or burning during urination. Do not discontinue any medications without consulting a doctor.

AzathioprineNatalizumab

Severe

How does the drug interact with ATZ 50 Tablet:
Taking ATZ 50 Tablet with Natalizumab can raise the risk of severe infections.

How to manage the interaction:
Although taking ATZ 50 Tablet and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.

AzathioprineInfliximab

Severe

How does the drug interact with ATZ 50 Tablet:
Coadministration of ATZ 50 Tablet and Infliximab can increase the risk or severity of developing infections.

How to manage the interaction:
Although taking Infliximab and ATZ 50 Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

AzathioprineVoclosporin

Severe

How does the drug interact with ATZ 50 Tablet:
Taking ATZ 50 Tablet with Voclosporin may lead to a higher chance of severe infections and certain cancers, such as skin cancer and lymph gland cancer (lymphoma).

How to manage the interaction:
Although taking ATZ 50 Tablet and Voclosporin together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice any symptoms like fever, chills, sore throat, muscle aches, blood in coughing fluid, red or inflamed skin, or body sores it is recommended to contact a doctor right away. Other symptoms such as weight loss, pain during urination, or difficulty breathing should also be reported promptly. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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