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Azaprin Tablet is an immunosuppressant primarily used to prevent kidney transplant rejection and manage the symptoms of active rheumatoid arthritis (a condition in which the immune system attacks the joints). It suppresses the overactive immune system by inhibiting the proliferation of certain white blood cells, thereby helping to prevent the body from rejecting newly transplanted organs. It also helps relieve joint pain and inflammation and slows disease progression in patients with rheumatoid arthritis.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Azaprin Tablet
  • Aim for at least five servings of a well-balanced diet per day that is full of vibrant fruits and vegetables.
  • Eat more whole foods, lean meats, and plant-based foods, and eat healthy fruits like bananas, oranges, and berries.
  • Limit alcohol intake and abstain from smoking to promote general wellbeing.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

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Drug-Drug Interactions

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Drug-Drug Interactions: Azaprin Tablet may interact with certain medicines, potentially increasing side effects or altering their effectiveness. Inform your doctor if you are taking any of the following:

  • Drugs used to treat gout (Allopurinol, Febuxostat)
    Potential effect: May increase the blood levels and effects of Azathioprine.
  • Immunosuppressants (Cladribine)
    Potential effect: May increase the risk of serious infections and certain cancers (such as skin and lymph gland cancer).
  • Disease-modifying anti-rheumatic drugs (Adalimumab, Baricitinib, Tofacitinib)
    Potential effect: May increase the risk of serious infections.
  • Drugs used to treat multiple sclerosis (Fingolimod, Teriflunomide)
    Potential effect: May increase the risk of developing anaemia, bleeding issues, and infections.
  • Anti-cancer medications (Mercaptopurine)
    Potential effect: May increase the risk of side effects.

Drug-Food Interactions: Avoid consuming alcohol while taking Azaprin Tablet , as it may cause increased dizziness.

Drug-Disease Interactions: Azaprin Tablet should be avoided or used with caution in people with:

  • Bone marrow depression (a serious condition in which the bone marrow produces fewer blood cells or platelets)
  • Serious bacterial, fungal, or viral infections
  • Kidney dysfunction
  • Liver disease

Drug-Drug Interactions

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How does the drug interact with Azaprin Tablet:
Taking Azaprin Tablet and Febuxostat together can increase the blood levels of Azaprin Tablet

How to manage the interaction:
Taking Azaprin Tablet with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Azaprin Tablet:
When Etanercept is used with Azaprin Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Azaprin Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AzathioprineCertolizumab
Severe
How does the drug interact with Azaprin Tablet:
When Azaprin Tablet and Certolizumab are taken together, they may raise the risk of severe infections

How to manage the interaction:
Although there is a possible interaction between Azaprin Tablet and certolizumab, you can take these medicines together if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azaprin Tablet:
The combined use of Azaprin Tablet with Mercaptopurine together can increase the risk of side effects.

How to manage the interaction:
Co-administration of Azaprin Tablet with Mercaptopurine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately, if you experience any symptoms such as bruising or bleeding, fever, chills, sore throat, flu symptoms, mouth sores, black urine, severe stomach pain, jaundice (yellowing of the skin or eyes), or severe nausea, vomiting, or diarrhea. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azaprin Tablet:
Coadministration of Azaprin Tablet and Infliximab can increase the risk or severity of developing infections.

How to manage the interaction:
Although taking Infliximab and Azaprin Tablet together can cause an interaction, it can be taken if a doctor has suggested it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azaprin Tablet:
The use of fingolimod with Azaprin Tablet may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azaprin Tablet with Fingolimod can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
AzathioprineGolimumab
Severe
How does the drug interact with Azaprin Tablet:
When Azaprin Tablet and Golimumab are taken together, they may raise the risk of severe infections

How to manage the interaction:
There may be a possibility of interaction between Azaprin Tablet and Golimumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm (a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Azaprin Tablet:
The use of cladribine with Azaprin Tablet can increase the risk of serious infections.

How to manage the interaction:
Although taking Azaprin Tablet and Cladribine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience symptoms fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain during urination, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Azaprin Tablet:
When Azaprin Tablet and Clozapine are taken together can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Azaprin Tablet with Clozapine can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
AzathioprineOlaratumab
Severe
How does the drug interact with Azaprin Tablet:
Using Azaprin Tablet together with olaratumab may increase the risk of serious infections.

How to manage the interaction:
Taking Olaratumab with Azaprin Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you need to take both medications together, it's important to closely monitor your health and get regular blood tests to check for any problems with your blood cells. If you notice any of these symptoms - like feeling weak, getting sick easily, having a fever or sore throat, or having trouble breathing - it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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