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Brufen 400 Tablet 20's
Brufen 400 Tablet 20's

Brufen 400 Tablet 20's is used to relieve mild to moderate pain, inflammation, and fever in adults and paediatrics above 6 months of age. It helps to treat conditions such as menstrual cramps, headache, neuralgia (nerve-related pain), migraine, back pain, dental pain, swelling and stiffness in joints and muscles, cold, and flu symptoms. It contains Ibuprofen, which works by reducing the production of chemicals prostaglandins that are produced at injury sites and cause pain and swelling. Thus, it reduces mild to moderate pain, inflammation, and fever. In some cases, you may experience certain common side effects such as indigestion, diarrhoea, constipation, flatulence (gas), general weakness, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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Health Queries

I am experiencing stomach pain after undergoing a C-section for childbirth. Is this normal, and how can I manage it?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Mild to moderate stomach pain after a C-section is common and usually due to surgical healing, gas, or muscle strain. You can manage it with rest, gentle movement, and warm compresses on the abdomen. Eat light, easily digestible food and stay hydrated to reduce gas and discomfort. Take only the pain medicines prescribed by your doctor. However, if the pain is severe or worsening, talk to your doctor.

I have knee pain sometimes. What may help relieve this problem?

Vikas Singh

Vikas Singh

M Pharmacy

Mild knee pain may occur due to strain, minor injury, or weakness of the surrounding muscles. Resting the knee, applying a warm compress, and doing gentle stretching exercises may help reduce discomfort. Maintaining a healthy weight can also reduce pressure on the knee joint. Consult a doctor if the pain becomes frequent, severe, or is associated with swelling.

I've had neck pain for 6 months and difficulty moving. What could be the cause?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Neck pain for 6 months along with difficulty moving could be due to issues like cervical spondylosis, nerve compression, poor posture, muscle strain, or even a slipped disc. Long-lasting pain like this should be checked by an orthopedic doctor. In the meantime, gentle stretching, good posture, warm compress, and avoiding sudden neck movements can help reduce discomfort.

Have a query?

Side effects of Brufen 400 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.

Drug-Drug Interactions

verifiedApollotooltip
IbuprofenKetorolac
Critical
IbuprofenMeloxicam
Critical

Drug-Drug Interactions

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IbuprofenKetorolac
Critical
How does the drug interact with Brufen 400 Tablet:
Taking Ketorolac and Brufen 400 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac and Brufen 400 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenMeloxicam
Critical
How does the drug interact with Brufen 400 Tablet:
Combining Meloxicam and Brufen 400 Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Meloxicam and Brufen 400 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenDeferasirox
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Deferasirox and Brufen 400 Tablet can increase the risk of developing gastrointestinal ulcers and bleeding.

How to manage the interaction:
Taking Deferasirox and Brufen 400 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black, tarry stools,swelling, shortness of breath, muscle cramps, tiredness, weakness, confusion, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenNaproxen
Severe
How does the drug interact with Brufen 400 Tablet:
Coadministration of Naproxen and Brufen 400 Tablet can increase the risk or severity of bleeding, ulceration, and rarely leading to serious blood loss.

How to manage the interaction:
Taking Naproxen and Brufen 400 Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenEverolimus
Severe
How does the drug interact with Brufen 400 Tablet:
The use of Everolimus and Brufen 400 Tablet can increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Everolimus and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenPralatrexate
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Pralatrexate and Brufen 400 Tablet can increase the risk of blood levels and side effects of Pralatrexate.

How to manage the interaction:
Co-administration of Pralatrexate and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like mouth ulcers or sores, vomiting, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, paleness, dizziness or fainting, unusual bruising or bleeding, infection, and flu-like symptoms (fever, chills, body aches, sore throat, muscle weakness), consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenDasatinib
Severe
How does the drug interact with Brufen 400 Tablet:
Coadministration of Dasatinib and Brufen 400 Tablet can increase the risk of bleeding.

How to manage the interaction:
Using Dasatinib and Brufen 400 Tablet together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenHuman immunoglobulin
Severe
How does the drug interact with Brufen 400 Tablet:
Taking Human immunoglobulin with Brufen 400 Tablet may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Brufen 400 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
IbuprofenPrasugrel
Severe
How does the drug interact with Brufen 400 Tablet:
Co-administration of Prasugrel and Brufen 400 Tablet can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prasugrel and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
IbuprofenTinzaparin
Severe
How does the drug interact with Brufen 400 Tablet:
The combined use of Tinzaparin and Brufen 400 Tablet can increase the risk of bleeding complications.

How to manage the interaction:
Co-administration of Tinzaparin and Brufen 400 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Nov 18, 2025 | 7:34 AM IST

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