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Bupron XL 300 Tablet is used to treat depression. Besides this, it is also used to help people stop smoking. It contains Bupropion, which works by increasing the levels of serotonin responsible for improving mood. In some cases, this medicine may cause side effects such as nausea, headache, dizziness, vomiting, difficulty sleeping, fever, constipation, and sweating. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Bupron XL 300 Tablet:
Co-administration of Metoclopramide with Bupron XL 300 Tablet can increase the levels of Metoclopramide and increase the risk or severity of developing seizures (fits).

How to manage the interaction:
Taking Metoclopramide with Bupron XL 300 Tablet is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Taking tranylcypromine with Bupron XL 300 Tablet can increase the risk of severe high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Bupron XL 300 Tablet can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Taking Safinamide with Bupron XL 300 Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Taking Safinamide with Bupron XL 300 Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience symptoms such as headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Taking Rasagiline with Bupron XL 300 Tablet can cause increased blood pressure.

How to manage the interaction:
Taking rasagiline with Bupron XL 300 Tablet is not recommended as it can result in an interaction but can be taken if a doctor has advised it. However, if you experience headache, sleep disturbances, tremor (shaking of hands & legs), restlessness, nervousness, anxiety, and rapid heartbeat contact a doctor. Do not discontinue any medications without consulting a doctor.
BupropionIsocarboxazid
Critical
How does the drug interact with Bupron XL 300 Tablet:
Using Bupron XL 300 Tablet together with isocarboxazid can cause blood pressure to get dangerously high.

How to manage the interaction:
Taking Isocarboxazid with Bupron XL 300 Tablet can cause an interaction, consult a doctor before taking it. Consult a doctor if you experience headache, sleep disturbances, tremor, restlessness, nervousness, anxiety, palpitation, and rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Taking Bupron XL 300 Tablet with amoxapine may raise the chance of seizures(fits), which can happen with either medicine. Furthermore, Bupron XL 300 Tablet can raise amoxapine levels in the blood, which may exacerbate other adverse effects.

How to manage the interaction:
Co- administration of Bupron XL 300 Tablet along with amoxapine can possibly lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Taking Bupron XL 300 Tablet with galantamine may raise the chance of seizures (fits).

How to manage the interaction:
Co-administration of Bupron XL 300 Tablet along with galantamine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience confusion, jerky movements, loss of consciousness, dizziness, muscle stiffness, palpitations, or shortness of breath, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Bupron XL 300 Tablet is capable of causing seizures (fits) and combining it with Prednisolone, may enhance the risk.

How to manage the interaction:
Although taking Prednisolone and Bupron XL 300 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. You should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
When Bupron XL 300 Tablet, is taken with granisetron it can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in body)

How to manage the interaction:
Co- administration of Bupron XL 300 Tablet along with granisetron can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications if you experience, confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Bupron XL 300 Tablet:
Bupron XL 300 Tablet is capable of causing seizures in rare cases, and combining it with cyclobenzaprine, may enhance the risk. If you are old, going through alcohol or drug withdrawal, have a history of seizures, or have a disorder affecting the central nervous system, such as a brain tumour or head trauma, you may be more vulnerable.

How to manage the interaction:
Co-administration of Bupron XL 300 Tablet along with cyclobenzaprine can possibly lead to an interaction, it can be taken if recommended by your doctor . While taking these medications, you should avoid or restrict your usage of alcohol. Avoid tasks that need mental attention, such as driving or operating dangerous machinery, until you have a better understanding of how the medications impact you.However, if you have any questions or concerns, see your doctor. Your doctor may be able to prescribe non-interfering alternatives. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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