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CONTRAPILL KIT TABLET

CONTRAPILL KIT TABLET is used for the medical termination of the pregnancy before 63 days after the first day of the last menses period. It also works in the second trimester of pregnancy. It contains Mifepristone and Misoprostol, which blocks the effects of the progesterone hormone required in women to continue the pregnancy. Also, it increases the womb's (uterus) contraction and dilates the cervix, thereby expelling the pregnancy. In some cases, you may experience side effects such as nausea, uterine cramps, vomiting, diarrhoea, infection following abortion, dizziness, and uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Contrapill Kit Tablet
  • Your doctor may reduce your medication dose gradually if you have too much cortisol, while still managing your condition.
  • Try hot baths, massages, and gentle exercises like water aerobics or tai chi to ease aches and pains.
  • Limit sodium and fatty foods to reduce health risks.
  • Consume foods rich in calcium, like dairy, leafy greens, fortified plant milk, and salmon, to support bone health.
  • Include sources of vitamin D in your meals, such as cod liver oil, egg yolks, fortified milk, and fatty fish like swordfish and salmon.
  • Make time for things you enjoy and set limits to avoid getting too tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Health Queries

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Drug-Drug Interactions

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Drug-Drug Interactions: CONTRAPILL KIT TABLET interacts with corticosteroids (dexamethasone), antifungal (ketoconazole, itraconazole), antibiotics (erythromycin, rifampicin),  anti-epileptic (phenytoin, phenobarbital, carbamazepine), immunosuppressants (cyclosporine, tacrolimus, sirolimus), medicines to treat migraine (ergotamine). So, CONTRAPILL KIT TABLET should not be taken along with these drugs.

Drug-Food Interactions: Please tell your doctor about all the Vitamins, herbs, and supplements you are taking as CONTRAPILL KIT TABLET may interact with them to produce unpleasant side effects. Also, CONTRAPILL KIT TABLET is known to interact with St John’s Wort (a natural remedy used to treat mild depression), and grapefruit juice.

Drug-Disease Interactions: CONTRAPILL KIT TABLET should be taken with caution in people who have a bleeding problem, confirmed or suspected ectopic pregnancy, heart problem, liver or kidney disease, vaginal bleeding, porphyria (an inherited blood disease that may cause nervous system or skin problems).

Mifepristone + MisoprostolDabigatran etexilate
Critical
Mifepristone + MisoprostolDalteparin
Critical

Drug-Drug Interactions

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Mifepristone + MisoprostolDabigatran etexilate
Critical
How does the drug interact with Contrapill Kit Tablet:
When Contrapill Kit Tablet is taken with Dabigatran etexilate, it may increase the risk of severe vaginal bleeding.

How to manage the interaction:
Taking Contrapill Kit Tablet with Dabigatran etexilate is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolDalteparin
Critical
How does the drug interact with Contrapill Kit Tablet:
Co-administration of Contrapill Kit Tablet with Dalteparin can increase the risk of vaginal bleeding.

How to manage the interaction:
Although taking Dalteparin with Contrapill Kit Tablet may lead to an interaction, they can be taken if a doctor prescribes it. Emergency medical attention may be needed for persistent, excessive bleeding. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolLurasidone
Critical
How does the drug interact with Contrapill Kit Tablet:
Co-administration of Lurasidone with Contrapill Kit Tablet can increase the levels of Lurasidone which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lurasidone with Contrapill Kit Tablet together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any abnormal muscle movements, seizures (fits), high blood sugar, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolPrednisolone
Critical
How does the drug interact with Contrapill Kit Tablet:
When Contrapill Kit Tablet is taken with Prednisolone, the effects of Prednisolone might be considerably reduced, which may be less effective in treating your condition.

How to manage the interaction:
Taking Prednisolone with Contrapill Kit Tablet is not recommended, they can be taken together if advised by a doctor. Do not discontinue the medication without consulting a doctor.
Mifepristone + MisoprostolTolvaptan
Critical
How does the drug interact with Contrapill Kit Tablet:
When Tolvaptan is taken with Contrapill Kit Tablet, it may increase the levels of Tolvaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan and Contrapill Kit Tablet together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
Mifepristone + MisoprostolTacrolimus
Critical
How does the drug interact with Contrapill Kit Tablet:
Taking Tacrolimus with Contrapill Kit Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk and/or severity of side effects.

How to manage the interaction:
Taking Tacrolimus with Mifepristone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
Mifepristone + MisoprostolMidazolam
Critical
How does the drug interact with Contrapill Kit Tablet:
Co-administration of Contrapill Kit Tablet and Midazolam may significantly increase Midazolam blood levels and effects, which increases the risk of side effects.

How to manage the interaction:
Although taking Contrapill Kit Tablet and Midazolam together may result in an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
Mifepristone + MisoprostolDefibrotide
Critical
How does the drug interact with Contrapill Kit Tablet:
Co-administration of Contrapill Kit Tablet with Defibrotide can increase the risk and severity of vaginal bleeding.

How to manage the interaction:
Taking Contrapill Kit Tablet with Defibrotide is not recommended, but it can be taken if prescribed by the doctor. However, if you experience excessive, prolonged vaginal bleeding, consult the doctor. Do not stop using any medications without talking to a doctor.
Mifepristone + MisoprostolTriamcinolone
Critical
How does the drug interact with Contrapill Kit Tablet:
Using Contrapill Kit Tablet with Triamcinolone can significantly reduce the effects of Triamcinolone.

How to manage the interaction:
Taking Triamcinolone with Contrapill Kit Tablet is not recommended but can be taken if prescribed by a doctor. However, if you notice any unusual symptoms contact a doctor. Do not discontinue any medications without consulting a doctor.
Mifepristone + MisoprostolPrasugrel
Critical
How does the drug interact with Contrapill Kit Tablet:
Co-administration of Contrapill Kit Tablet with Prasugrel can increase the chance of experiencing vaginal bleeding.

How to manage the interaction:
Taking Prasugrel with Contrapill Kit Tablet can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience prolonged, heavy bleeding, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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MIFEPRISTONE-200MG+MISOPROSTOL-200MCGFruit juices, Fruits
Moderate

Drug-Food Interactions

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MIFEPRISTONE-200MG+MISOPROSTOL-200MCGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or grapefruit juice along with Contrapill Kit Tablet may cause the medication's blood levels to rise to unwanted levels and raise the chance of adverse effects. Avoid taking grapefruit or grapefruit juice along with Contrapill Kit Tablet as this can raise the chance of adverse effects. However, consult a doctor if you experience headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, hypokalemia (low blood potassium), fluid retention, swelling, and high blood pressure.

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