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DUB 5 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, it may be used in the treatment of breast cancer. It contains Norethisterone, which works by restoring the hormone levels in the body. In some cases, this medicine may cause side effects such as unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, and diarrhoea. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Obsurge Biotech Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About DUB 5 mg Tablet

DUB 5 mg Tablet is used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis.

DUB 5 mg Tablet contains Norethisterone, which mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining.

Common side effects include unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhoea, headache, breast pain, and tenderness. Most of these side effects do not require medical attention. However, if the side effects persist, please consult your doctor.

If you are allergic to DUB 5 mg Tablet or any other medicines, please tell your doctor. DUB 5 mg Tablet is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking DUB 5 mg Tablet . It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking DUB 5 mg Tablet .

Uses of DUB 5 mg Tablet

DUB 5 mg Tablet is used to treat endometriosis. The detailed uses of DUB 5 mg Tablet are as follows:

  • Menstrual Cycle Regulation: DUB 5 mg Tablet is commonly used to regulate irregular menstrual cycles or to induce menstruation in women experiencing amenorrhea (absence of periods).
  • Management of Endometriosis: DUB 5 mg Tablet is also effective in managing endometriosis, a condition where uterine-like tissue grows outside the uterus, leading to pain and irregular bleeding.
  • Support in Hormone Replacement Therapy: In postmenopausal women, DUB 5 mg Tablet is often combined with estrogen therapy to prevent endometrial hyperplasia (thickening of the uterine lining), which can result from estrogen use alone.
  • Relieve Menstrual problems: DUB 5 mg Tablet is sometimes prescribed to alleviate symptoms of premenstrual syndrome (PMS) and to provide relief from excessive bleeding or pain during menstruation.

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Directions for Use

  • DUB 5 mg Tablet can be taken with or without food, or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow DUB 5 mg Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Key Benefits

  • DUB 5 mg Tablet contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone.
  • It restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps treat menstrual disorders.
  • DUB 5 mg Tablet is also used in the treatment of breast cancer.

How DUB 5 mg Tablet Works

DUB 5 mg Tablet contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of DUB 5 mg Tablet

Take DUB 5 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, breast enlargement and vaginal bleeding. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • If you are allergic to DUB 5 mg Tablet or any other medicines, please tell your doctor.
  • DUB 5 mg Tablet is not recommended for pregnant women as it may harm an unborn baby.
  • If you are breastfeeding, consult a doctor before taking DUB 5 mg Tablet .
  • It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking DUB 5 mg Tablet .
  • You are advised to stop smoking while taking DUB 5 mg Tablet as it may increase the risk of adverse effects.
  • If you are about to undergo any surgery, please inform your doctor that you are taking DUB 5 mg Tablet as it may increase the effect of certain anesthetics.
  • If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking DUB 5 mg Tablet and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with DUB 5 mg Tablet:
The combined use of DUB 5 mg Tablet and phenobarbital can reduce the blood levels and effects of DUB 5 mg Tablet.

How to manage the interaction:
Although taking phenobarbital and DUB 5 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with DUB 5 mg Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking DUB 5 mg Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with DUB 5 mg Tablet:
Using Etretinate and DUB 5 mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking DUB 5 mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
How does the drug interact with DUB 5 mg Tablet:
Taking griseofulvin with DUB 5 mg Tablet may reduce blood levels and the effects of DUB 5 mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and DUB 5 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with DUB 5 mg Tablet:
Coadministration of DUB 5 mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking DUB 5 mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with DUB 5 mg Tablet:
Co-administration of DUB 5 mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking DUB 5 mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with DUB 5 mg Tablet:
Coadministration of Phenytoin and DUB 5 mg Tablet may decrease the blood levels of DUB 5 mg Tablet, which may make DUB 5 mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and DUB 5 mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. If you experience any symptoms, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with DUB 5 mg Tablet:
Coadministration of DUB 5 mg Tablet with Dabrafenib can reduce the metabolism and decrease the levels of DUB 5 mg Tablet in the body.

How to manage the interaction:
Taking DUB 5 mg Tablet with Dabrafenib together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of hot flashes, vaginal dryness, or abnormal bleeding, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneBoceprevir
Severe
How does the drug interact with DUB 5 mg Tablet:
Using Boceprevir and DUB 5 mg Tablet together can reduce the blood levels and decrease the effectiveness of norethindrone.

How to manage the interaction:
Combining Boceprevir with DUB 5 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, abnormal bleeding, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
NorethisteroneFosamprenavir
Severe
How does the drug interact with DUB 5 mg Tablet:
Using norethindrone together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Taking DUB 5 mg Tablet with Fosamprenavir together can result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing any symptoms, it's important to reach out to a doctor right away. They can recommend other options that won't interfere with your medication. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of DUB 5 mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the DUB 5 mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the DUB 5 mg Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

[PROGESTIN]

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Alcohol

Consult your doctor

The interaction of DUB 5 mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using DUB 5 mg Tablet .

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Pregnancy

Unsafe

DUB 5 mg Tablet is a category X pregnancy drug and is not recommended for use during pregnancy as it may harm the unborn baby. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Consult your doctor

DUB 5 mg Tablet is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Safe if prescribed

DUB 5 mg Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Unsafe

DUB 5 mg Tablet is not recommended if you have liver disease. However, if you have any concerns regarding this, please consult a doctor.

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Kidney

Caution

Take DUB 5 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

DUB 5 mg Tablet is not recommended for use in children under 18 years.

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Heart

Caution

DUB 5 mg Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking DUB 5 mg Tablet .

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Geriatrics

Unsafe

DUB 5 mg Tablet is generally not recommended for elderly patients due to an increased risk of side effects and reduced effectiveness.

Country of origin

INDIA

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - DUB0006

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