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Etoposide 50 mg Capsule 8's
Etoposide 50 mg Capsule is used to treat various types of cancer, including testicular cancer, small cell lung cancer, blood cancer, ovarian cancer, and lymphoma. It contains Etoposide which works by preventing the growth and spread of cancer cells. In some cases, this medicine may cause side effects such as temporary hair loss, nausea and vomiting, loss of appetite, diarrhoea, and irregular heartbeat. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Side effects of Etoposide 50 mg Capsule
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
EtoposideAdalimumab
Severe

Drug-Drug Interactions

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EtoposideRotavirus vaccine
Critical
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When the Rotavirus vaccine is used together with Etoposide 50 mg Capsule, it may not work as well.

How to manage the interaction:
Taking Etoposide 50 mg Capsule with the Rotavirus vaccine can cause an, please consult doctor before taking it. You may be at risk of acquiring an infection from the vaccination or having a decreased response of the vaccine depending on the dose and length of time you have been on Etoposide 50 mg Capsule. Do not discontinue any medications without a doctor's advice.
EtoposideAdalimumab
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When Etoposide 50 mg Capsule is used with Adalimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Etoposide 50 mg Capsule and Adalimumab together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideLeflunomide
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When Etoposide 50 mg Capsule is used with Leflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Leflunomide and Etoposide 50 mg Capsule, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideFingolimod
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When Etoposide 50 mg Capsule is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Etoposide 50 mg Capsule with Fingolimod together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideCladribine
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
Taking Cladribine with Etoposide 50 mg Capsule can increase the risk of serious infections.

How to manage the interaction:
Taking Etoposide 50 mg Capsule with Cladribine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating, make sure to contact the doctor right away. Do not stop using any medications without a doctor's advice.
EtoposideIdelalisib
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When Etoposide 50 mg Capsule is used with Idelalisib, Idelalisib may increase the blood levels and effects of Etoposide 50 mg Capsule.

How to manage the interaction:
Taking Etoposide 50 mg Capsule with Idelalisib together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EtoposideTeriflunomide
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When Etoposide 50 mg Capsule is used with Teriflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etoposide 50 mg Capsule with Teriflunomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EtoposideNatalizumab
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
Taking Etoposide 50 mg Capsule with natalizumab, especially taking both simultaneously with little to no time in between, may raise the risk of serious infections.

How to manage the interaction:
Although taking Etoposide 50 mg Capsule and Natalizumab together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. progressive weakening on one side of your body, clumsiness of limbs, visual disturbance, disorientation, or changes in your thinking, memory, or personality. Do not stop using any medications without talking to a doctor.
EtoposideVoclosporin
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
When Etoposide 50 mg Capsule is used with Voclosporin, the risk of severe infections, as well as certain cancers including skin cancer and cancer of the lymph glands (lymphoma), increases.

How to manage the interaction:
Although taking Etoposide 50 mg Capsule and Voclosporin together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, If you experience a fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
EtoposideThalidomide
Severe
How does the drug interact with Etoposide 50 mg Capsule 50 mg Capsule:
Taking thalidomide together with Etoposide 50 mg Capsule may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Etoposide 50 mg Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ETOPOSIDE-50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ETOPOSIDE-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit

How to manage the interaction:
Consumption of Grapefruit, grapefruit juice with Etoposide 50 mg Capsule, blocks metabolism, which might raise Etoposide 50 mg Capsule levels in the blood. Avoid the consumption of grapefruit juice while taking Etoposide 50 mg Capsule.

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