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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Heofulvin 500 mg Tablet 10's is used to treat fungal infections of the skin like ringworm, jock itch, athlete's foot, and fungal infections of nails and hair. It contains Griseofulvin, which works by binding to the keratin (a protein that is formed in the cells of the skin, hair follicles, and nail bed) and inhibits the growth and multiplication of fungal cells. Thereby, it prevents newly grown keratin from being infected by fungal cells. The infected keratin dies and sheds from the body, leaving new healthy keratin. Some people may experience side effects such as nausea, diarrhoea, headache, and discomfort in the stomach. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Heofulvin 500 mg Tablet:
When Ranolazine is taken with Heofulvin 500 mg Tablet, may significantly reduce the blood levels of Ranolazine, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Heofulvin 500 mg Tablet with Ranolazine is not recommended, they can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Heofulvin 500 mg Tablet:
Using drospirenone together with Heofulvin 500 mg Tablet may decrease the blood levels and effects of drospirenone.

How to manage the interaction:
Although taking Heofulvin 500 mg Tablet and Drospirenone together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, or if you think you might be pregnant while using birth control, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Heofulvin 500 mg Tablet:
Using levonorgestrel with Heofulvin 500 mg Tablet may reduce levonorgestrel blood levels and effects.

How to manage the interaction:
Although taking levonorgestrel and Heofulvin 500 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you use hormone replacement treatment(levonorgestrel) for menopause, consult the doctor if your symptoms do not improve or if you begin to bleed abnormally. Do not discontinue any medications without consulting a doctor.
GriseofulvinUlipristal
Severe
How does the drug interact with Heofulvin 500 mg Tablet:
When taken together the blood levels of ulipristal may be significantly decreased by Heofulvin 500 mg Tablet, which might impair the effectiveness of the medicine in treating the disease.

How to manage the interaction:
Although there is a possible interaction between Heofulvin 500 mg Tablet and Ulipristal, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Heofulvin 500 mg Tablet:
Taking Heofulvin 500 mg Tablet with norethisterone may reduce blood levels and the effects of norethisterone.

How to manage the interaction:
Although there is a possible interaction between Heofulvin 500 mg Tablet and Norethisterone, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GriseofulvinAminolevulinic acid
Severe
How does the drug interact with Heofulvin 500 mg Tablet:
Aminolaevulinic acid sensitizes skin to bright sunlight and taking it with another medication that can have the same effect (i.e., photosensitivity) such as Heofulvin 500 mg Tablet may increase chance of getting a serious sunburn.

How to manage the interaction:
Although taking Heofulvin 500 mg Tablet and Aminolaevulinic acid together can cause an interaction, it can be taken if a doctor has suggested it. After treatment, avoid exposing your eyes and skin to sunlight or intense interior lights for 48 hours. Do not discontinue any medications without consulting a doctor.
GriseofulvinEtonogestrel
Severe
How does the drug interact with Heofulvin 500 mg Tablet:
Taking Heofulvin 500 mg Tablet with etonogestrel may reduce blood levels and the effects of etonogestrel.

How to manage the interaction:
Although there is a possible interaction between Heofulvin 500 mg Tablet and Etonogestrel, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, or if you think you might be pregnant while using birth control, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Heofulvin 500 mg Tablet:
Taking ethinyl estradiol with Heofulvin 500 mg Tablet may reduce blood levels and the effects of ethinyl estradiol.

How to manage the interaction:
Although taking Ethinylestradiol and Heofulvin 500 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you use hormone replacement therapy (ethinyl estradiol) for menopause, inform a doctor if your symptoms are no longer controlled or if you deal with unusual bleeding. Do not stop using any medications without a doctor's advice.
How does the drug interact with Heofulvin 500 mg Tablet:
When Everolimus is taken with Heofulvin 500 mg Tablet, it may decrease the blood levels of everolimus, which may make everolimus less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Everolimus and Heofulvin 500 mg Tablet, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Heofulvin 500 mg Tablet:
When Desogestrel is used with Heofulvin 500 mg Tablet may decrease the effectiveness of Desogestrel.

How to manage the interaction:
Co-administration of Desogestrel with Heofulvin 500 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. If you experience abnormal menstruation, dryness of the vagina, or increased hot flushes or if you're looking for other birth control options, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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