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संघटन :
इब्रुटिनिब-140एमजी
निर्माता/विपणक :
जॉनसन एंड जॉनसन लिमिटेड.
उपभोग प्रकार :
मौखिक
वापसी नीति :
वापसी योग्य नहीं
को या उसके बाद समाप्त हो जाएगा :
Jan-27
Drug-Drug Interactions
IbrutinibFosamprenavir
Severe
Drug-Drug Interactions
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IbrutinibFosamprenavir
Severe
How does the drug interact with Ibrunat Capsule:
Taking Fosamprenavir with Ibrunat Capsule may increase the levels of Ibrunat Capsule.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and Fosamprenavir, but it can be taken if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor. Do not discontinue any medications without a doctor's advice.
Taking Fosamprenavir with Ibrunat Capsule may increase the levels of Ibrunat Capsule.
How to manage the interaction:
There may be a possibility of interaction between Ibrunat Capsule and Fosamprenavir, but it can be taken if prescribed by a doctor. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, muscle aches, breathing difficulty, blood in coughing fluid, red or inflamed skin, body sores, pain or burning during urination, nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, irregular heart rhythm, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Ibrunat Capsule:
Taking Ibrunat Capsule with imatinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Imatinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, nausea, vomiting, loss of appetite, fluid retention, swelling, irregular heartbeat, you should consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Taking Ibrunat Capsule with imatinib may increase the levels of Ibrunat Capsule.
How to manage the interaction:
Taking Ibrunat Capsule with Imatinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, nausea, vomiting, loss of appetite, fluid retention, swelling, irregular heartbeat, you should consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
IbrutinibTinzaparin
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Tinzaparin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Tinzaparin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Tinzaparin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Tinzaparin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Taking Clopidogrel with Ibrunat Capsule can increase the risk of bleeding.
How to manage the interaction:
Although there is an interaction between Clopidogrel and Ibrunat Capsule, they can be taken together if prescribed by a doctor. However, if you experience any feeling dizzy or lightheaded, red or black, sticky stools, severe headache, or weakness, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
Taking Clopidogrel with Ibrunat Capsule can increase the risk of bleeding.
How to manage the interaction:
Although there is an interaction between Clopidogrel and Ibrunat Capsule, they can be taken together if prescribed by a doctor. However, if you experience any feeling dizzy or lightheaded, red or black, sticky stools, severe headache, or weakness, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
IbrutinibAnistreplase
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Anistreplase can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Anistreplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Anistreplase can increase the risk of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Anistreplase together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Mefenamic acid with Ibrunat Capsule can increase the risk or severity of bleeding, leading to serious blood loss.
How to manage the interaction:
Taking Mefenamic acid with Ibrunat Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Co-administration of Mefenamic acid with Ibrunat Capsule can increase the risk or severity of bleeding, leading to serious blood loss.
How to manage the interaction:
Taking Mefenamic acid with Ibrunat Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of unusual bleeding or bruising, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Ibrunat Capsule:
Taking Ticagrelor with Ibrunat Capsule can increase the risk or severity of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Ticagrelor together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Taking Ticagrelor with Ibrunat Capsule can increase the risk or severity of bleeding.
How to manage the interaction:
Taking Ibrunat Capsule with Ticagrelor together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule and Deferiprone can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Deferiprone, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Ibrunat Capsule and Deferiprone can increase the risk of developing serious infections.
How to manage the interaction:
Although there is an interaction, Ibrunat Capsule can be taken with Deferiprone, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
IbrutinibRifapentine
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Rifapentine may decrease the blood levels of Ibrunat Capsule, which may make Ibrunat Capsule less effective in treating your condition.
How to manage the interaction:
Although taking Ibrunat Capsule and Rifapentine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
Co-administration of Rifapentine may decrease the blood levels of Ibrunat Capsule, which may make Ibrunat Capsule less effective in treating your condition.
How to manage the interaction:
Although taking Ibrunat Capsule and Rifapentine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
IbrutinibDesirudin
Severe
How does the drug interact with Ibrunat Capsule:
Co-administration of Ibrunat Capsule with Desirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Desirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Co-administration of Ibrunat Capsule with Desirudin can increase the risk of bleeding leading to serious blood loss.
How to manage the interaction:
Taking Ibrunat Capsule with Desirudin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Drug-Food Interactions
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IBRUTINIB-140MGGrapefruit and Grapefruit Juice, Herbal products/medicines
Common Foods to Avoid:
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Grapefruit Juice, Grapefruit, St. John’S Wort
How to manage the interaction:
Consumption of grape fruit or its products, St. John’S Wort during Ibrunat Capsule treatment may lead to an interaction. Avoid consumption of grape fruit or its products, St. John’S Wort while on therapy with Ibrunat Capsule.
Product Substitutes
शराब
Consult your doctor
यह ज्ञात नहीं है कि शराब इब्रुनैट कैप्सूल 30's को प्रभावित करती है या नहीं। हालाँकि, इब्रुनैट कैप्सूल 30's के साथ उपचार के दौरान शराब के सेवन से बचें क्योंकि इससे आपकी स्थिति और खराब हो सकती है।
गर्भावस्था
Unsafe
इब्रुटिनिब गर्भावस्था श्रेणी डी से संबंधित है। इब्रुनैट कैप्सूल 30's का उपयोग गर्भावस्था के दौरान नहीं किया जाना चाहिए। इब्रुनैट कैप्सूल 30's के साथ उपचार के दौरान प्रभावी गर्भनिरोधक का उपयोग करें और गर्भावस्था से बचें।
स्तनपान
Unsafe
इब्रुनैट कैप्सूल 30's लेते समय स्तनपान कराने से बचें।
ड्राइविंग
Caution
इब्रुनैट कैप्सूल 30's चक्कर आना और थकान का कारण बन सकता है। यदि आपको कोई साइड इफ़ेक्ट महसूस होता है जिससे आपकी ऐसा करने की क्षमता कम हो सकती है तो गाड़ी न चलाएं या मशीनरी न चलाएं।
जिगर
Caution
यदि आपको मध्यम या गंभीर आधारभूत यकृत क्षति है तो इब्रुनैट कैप्सूल 30's लेने से बचें। हल्के यकृत क्षति वाले रोगियों में खुराक समायोजन की आवश्यकता हो सकती है। यदि आपको यकृत रोग का इतिहास है, तो डॉक्टर को सूचित करें।
किडनी
Consult your doctor
यदि आपको किडनी की बीमारी का इतिहास है, तो इब्रुनैट कैप्सूल 30's लेने से पहले अपने डॉक्टर को सूचित करें।
बच्चे
Unsafe
इब्रुनैट कैप्सूल 30's की बच्चों के लिए अनुशंसा नहीं की जाती है क्योंकि सुरक्षा और प्रभावशीलता स्थापित नहीं की गई है।
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