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Meftal-250 DT Tablet is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods. It contains Mefenamic acid, which works by blocking the effect of chemical messengers that cause pain and inflammation. In some cases, you may experience certain common side effects such as abdominal pain, nausea, vomiting, diarrhoea, heartburn and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking pain killers (aspirin, ibuprofen, celecoxib, diclofenac, naproxen), anti-gout (probenecid), immunosuppressants (cyclosporine, tacrolimus), anticoagulants (warfarin, heparin), anti-rheumatoid (methotrexate), anti-HIV (zidovudine), anti-depressant (duloxetine, lithium, fluoxetine, sertraline), or steroid medication (mifepristone).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have a history of peptic ulcers, bleeding disorders, asthma, fluid retention, gastrointestinal toxicity, rash, renal toxicity, thrombosis, anaemia, heart failure, liver toxicity, high blood pressure, platelet aggregation inhibition, or hyperkalemia (high potassium levels).

Drug-Drug Interactions

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How does the drug interact with Meftal-250 DT Tablet:
Coadministration of Meftal-250 DT Tablet with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Meftal-250 DT Tablet with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Meftal-250 DT Tablet:
Co-administration of Meftal-250 DT Tablet with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Meftal-250 DT Tablet with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
How does the drug interact with Meftal-250 DT Tablet:
Using cabozantinib together with Meftal-250 DT Tablet may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Meftal-250 DT Tablet and Cabozantinib, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like blood clotting problems, excessive bleeding, or severe headaches, it's best to contact a doctor right away. They can help address any complications and provide the necessary support. Do not stop using any medications without talking to a doctor.
How does the drug interact with Meftal-250 DT Tablet:
The combined use of Meftal-250 DT Tablet and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Meftal-250 DT Tablet and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Meftal-250 DT Tablet:
Coadministration of cidofovir with Meftal-250 DT Tablet can increase the risk of kidney problems.

How to manage the interaction:
Although taking Meftal-250 DT Tablet and cidofovir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidLomitapide
Severe
How does the drug interact with Meftal-250 DT Tablet:
Coadministration of Meftal-250 DT Tablet with Lomitapide can cause liver damage.

How to manage the interaction:
Co-administration of Meftal-250 DT Tablet with Lomitapide can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
How does the drug interact with Meftal-250 DT Tablet:
The combined use of Indometacin and Meftal-250 DT Tablet can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
Taking Indometacin with Meftal-250 DT Tablet together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Meftal-250 DT Tablet:
Coadministration of Meftal-250 DT Tablet with Dabigatran can increase the risk or severity of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Meftal-250 DT Tablet with Dabigatran etexilate together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Meftal-250 DT Tablet:
Using Meftal-250 DT Tablet and baricitinib together may increase the risk of gastrointestinal perforation (a serious health condition where a hole develops through the stomach or intestine).

How to manage the interaction:
Co-administration of Meftal-250 DT Tablet with Baricitinib can result in an interaction, but it can be taken if your doctor has advised it. If you notice any signs like severe stomach pain, fever, or vomiting, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Meftal-250 DT Tablet:
Meftal-250 DT Tablet and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Meftal-250 DT Tablet and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without first consulting your doctor, never stop taking any medications.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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