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Jan-27
Drug-Drug Interactions
AmlodipineDantrolene
Critical
Severe
Drug-Drug Interactions
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AmlodipineDantrolene
Critical
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Met XL AM 25/5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Using Met XL AM 25/5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).
How to manage the interaction:
Taking Met XL AM 25/5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Taking simvastatin with Met XL AM 25/5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Met XL AM 25/5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
Taking simvastatin with Met XL AM 25/5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).
How to manage the interaction:
Although taking Met XL AM 25/5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineFosphenytoin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
When Met XL AM 25/5 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Met XL AM 25/5 Tablet, which may make Met XL AM 25/5 Tablet less effective.
How to manage the interaction:
Although taking Met XL AM 25/5 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
When Met XL AM 25/5 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Met XL AM 25/5 Tablet, which may make Met XL AM 25/5 Tablet less effective.
How to manage the interaction:
Although taking Met XL AM 25/5 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and phenytoin together may drastically lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although Met XL AM 25/5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Using Met XL AM 25/5 Tablet and phenytoin together may drastically lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although Met XL AM 25/5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Ceritinib together with Met XL AM 25/5 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Ceritinib together with Met XL AM 25/5 Tablet can slow heart rate and increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with Ceritinib, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, or an irregular heartbeat, consult the doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet and rifampicin together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Met XL AM 25/5 Tablet and rifampicin together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and rifabutin together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
Using Met XL AM 25/5 Tablet and rifabutin together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with rifabutin, but it can be taken if a doctor has advised it. Consult the doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of lemborexant and Met XL AM 25/5 Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Met XL AM 25/5 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Coadministration of lemborexant and Met XL AM 25/5 Tablet may increase the blood levels of lemborexant.
How to manage the interaction:
Although co-administration of Met XL AM 25/5 Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet with itraconazole may significantly raise the blood levels and effects of Met XL AM 25/5 Tablet.
How to manage the interaction:
Met XL AM 25/5 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
Coadministration of Met XL AM 25/5 Tablet with itraconazole may significantly raise the blood levels and effects of Met XL AM 25/5 Tablet.
How to manage the interaction:
Met XL AM 25/5 Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet and carbamazepine together may significantly reduce Met XL AM 25/5 Tablet blood levels, making the medicine less effective.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Met XL AM 25/5 Tablet and carbamazepine together may significantly reduce Met XL AM 25/5 Tablet blood levels, making the medicine less effective.
How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate
Drug-Food Interactions
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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.
Grapefruit Juice, Grapefruit
How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.
Product Substitutes
शराब
Unsafe
आपको मेट एक्सएल एएम 25/5 टैबलेट 20's के साथ शराब न लेने की सलाह दी जाती है क्योंकि इससे कोई परस्पर क्रिया हो सकती है, जिससे मेट एक्सएल एएम 25/5 टैबलेट 20's के चिकित्सीय प्रभाव कम हो सकते हैं। अगर आपको कोई चिंता है तो कृपया अपने डॉक्टर से सलाह लें।
गर्भावस्था
Caution
मेट एक्सएल एएम 25/5 टैबलेट 20's का उपयोग गर्भावस्था में केवल तभी किया जा सकता है जब इसकी पूरी तरह से आवश्यकता हो। यदि आपको कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
स्तनपान
Caution
स्तनपान के दौरान मेट एक्सएल एएम 25/5 टैबलेट 20's का उपयोग करने की अनुशंसा नहीं की जाती है। यदि आपको कोई चिंता है तो कृपया अपने डॉक्टर से परामर्श करें।
ड्राइविंग
Caution
मेट एक्सएल एएम 25/5 टैबलेट 20's के कारण चक्कर आ सकता है या सतर्कता में कमी आ सकती है, जिससे आपकी गाड़ी चलाने की क्षमता प्रभावित हो सकती है।
जिगर
Caution
मेट एक्सएल एएम 25/5 टैबलेट 20's को उन लोगों के लिए उपयोग करने की अनुशंसा नहीं की जाती है जिन्हें पहले से ही लीवर की बीमारी है। किसी भी चिंता के मामले में कृपया अपने डॉक्टर से परामर्श करें।
किडनी
Caution
मेट एक्सएल एएम 25/5 टैबलेट 20's संभवतः गुर्दे के लिए सुरक्षित है, लेकिन गुर्दे की कमी वाले लोगों को इसका उपयोग सावधानी से करना चाहिए। किसी भी चिंता के मामले में कृपया अपने डॉक्टर से परामर्श करें।
बच्चे
Unsafe
मेट एक्सएल एएम 25/5 टैबलेट 20's को 12 वर्ष से कम उम्र के बच्चों में उपयोग के लिए अनुशंसित नहीं किया जाता है। यदि आपको कोई चिंता है तो कृपया अपने चिकित्सक से परामर्श करें।
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