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compositionComposition:AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MG
prescription
Prescription Medicine
info
Amlopin-M 25 Tablet 10's
Amlopin-M 25 Tablet 10's
Amlopin-M 25 Tablet 10's

Amlopin-M 25 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as a heart attack and stroke. It is a combination medicine which suppresses the contraction of blood vessels and promotes smooth blood flow. It also alters the response to nerve impulses in the heart, thereby making the heart pump blood more easily. Common side effects include headache, nausea, dizziness, stomach upset, and weakness.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MG

Manufacturer/Marketer :

USV Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Amlopin-M 25 Tablet

Amlopin-M 25 Tablet is used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest.

Amlopin-M 25 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow.

In some cases, Amlopin-M 25 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention. However, talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Avoid consuming alcohol with Amlopin-M 25 Tablet as there may be an interaction. Amlopin-M 25 Tablet  may cause dizziness; therefore, drive only if you are alert.

Uses of Amlopin-M 25 Tablet

Amlopin-M 25 Tablet is used in the treatment of hypertension and angina pectoris. The detailed uses of Amlopin-M 25 Tablet are as follows:

  • Treatment of Hypertension: Amlopin-M 25 Tablet lowers blood pressure by relaxing blood vessels and slowing heart rate.
  • Management of Angina (Chest Pain): Amlopin-M 25 Tablet improves blood flow to the heart, reducing pain and discomfort.
  • Support in Chronic Heart Failure: Amlopin-M 25 Tablet reduces the workload on the heart and improves pumping efficiency.
  • Control of Abnormal Heart Rhythms: Amlopin-M 25 Tablet helps regulate heartbeat and prevent arrhythmias.

Key Benefits

  • Amlopin-M 25 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine.
  • It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. 
  • Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate.
  • Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries.
  • In addition, Amlopin-M 25 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.
Side effects of Amlopin-M 25 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

Directions for Use

  • Take Amlopin-M 25 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Amlopin-M 25 Tablet Works

Amlopin-M 25 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Amlopin-M 25 Tablet helps treat high blood pressure.
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Alcohol

Unsafe

You are advised not to take alcohol with Amlopin-M 25 Tablet as there may be an interaction, reducing the therapeutic effects of Amlopin-M 25 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Amlopin-M 25 Tablet may be used in pregnancy only if absolutely warranted. Please consult your doctor if you have any concerns.

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Breast Feeding

Consult your doctor

Amlopin-M 25 Tablet is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Amlopin-M 25 Tablet may cause dizziness or loss of alertness, which may affect your ability to drive.

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Liver

Consult your doctor

Amlopin-M 25 Tablet is not recommended for use in those with established liver disease. Please consult your doctor in case of any concerns.

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Kidney

Consult your doctor

Amlopin-M 25 Tablet is probably safe on the kidney but should be used with caution in those with renal impairment. Please consult your doctor in case of any concerns.

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Children

Unsafe

Amlopin-M 25 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

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Heart

Caution

Amlopin-M 25 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Caution

Amlopin-M 25 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Amlopin-M 25 Tablet .

What if I have taken an overdose of Amlopin-M 25 Tablet

Do not take more than the prescribed dose. Overdose of Amlopin-M 25 Tablet may cause low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin. Seek immediate medical attention if you suspect that you might have taken an overdose of this medicine.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Amlopin-M 25 Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Amlopin-M 25 Tablet may cause cold extremities.

Have a query?

How Soon It Starts Working

  • The time required for Amlopin-M 25 Tablet to start to work: The time required for Amlopin-M 25 Tablet to show its action is unknown. 
  • The time for which the effects of Amlopin-M 25 Tablet last: The duration of action for Amlopin-M 25 Tablet is clinically unknown.

What if you forget to take Amlopin-M 25 Tablet

If you miss a dose of Amlopin-M 25 Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Amlopin-M 25 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Amlopin-M 25 Tablet should not be used in case of any known allergy to either of the components. 
  • Amlopin-M 25 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis.
  • Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease.
  • Consult your doctor before using Amlopin-M 25 Tablet during pregnancy or breastfeeding.
  • Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure.
  • Amlopin-M 25 Tablet may interact with alcohol; please consult your doctor before use.
  • Amlopin-M 25 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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Drug-Drug Interactions: Amlopin-M 25 Tablet may interact with monoamine oxidase inhibitors, antiarrhythmic agents (quinidine, propafenone), anti-depressant (fluoxetine, paroxetine), anti-hypertensive (diltiazem, clonidine, verapamil), antibiotic (erythromycin), anti-fungal (ketoconazole, itraconazole), anti-viral (ritonavir), cardiac glycoside (digitalis), 

Drug-Food Interactions: Amlopin-M 25 Tablet can interact with grapefruit juice, fish oil and castor oil.

Drug-Disease Interactions: Amlopin-M 25 Tablet should be used with caution in patients with a known hypersensitivity disorder, shock, COPD, diabetes mellitus, heart failure, liver cirrhosis, myasthenia gravis, phaeochromocytoma, chronic diarrhoea, thromboembolic disorder, cardiovascular disorder and/or dry eyes.

Amlodipine + MetoprololDantrolene
Critical
Amlodipine + MetoprololSaquinavir
Severe

Drug-Drug Interactions

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Amlodipine + MetoprololDantrolene
Critical
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Amlodipine and Metoprolol together with Dantrolene may increase the risk of side effects.

How to manage the interaction:
Taking Amlodipine with Dantrolene can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
Amlodipine + MetoprololSaquinavir
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Amlodipine and Metoprolol with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Amlodipine and Metoprolol with Saquinavir, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Amlodipine + MetoprololClonidine
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Clonidine and Metoprolol may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metoprolol, you can take these medicines together if prescribed by a doctor. However, if you experience slow heartbeat, headaches contact a doctor. Do not stop using any medications without talking to a doctor.
Amlodipine + MetoprololSirolimus
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Amlodipine and Metoprolol with Sirolimus may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Amlodipine and Metoprolol with Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any mouth sores and inflammation, abdominal pain, breathing problems. Do not stop using any medications without a doctor's advice.
Amlodipine + MetoprololArtemether
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Amlodipine and Metoprolol with Artemether may increase the blood levels and effects of Metoprolol activity.

How to manage the interaction:
Taking Amlodipine and Metoprolol with Artemether together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Amlodipine + MetoprololAcebutolol
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Taking Amlodipine and Metoprolol with Acebutolol can increase the risk of low blood pressure.

How to manage the interaction:
Although taking Amlodipine and Metoprolol with acebutolol can result in an interaction, they can be taken if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
Amlodipine + MetoprololItraconazole
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Amlodipine and Metoprolol with Itraconazole may significantly raise the blood levels and effects of Amlodipine.

How to manage the interaction:
Although Amlodipine and Metoprolol with Itraconazole may interact, they can be used together if prescribed by a doctor. Consult a doctor if you develop irregular heart rhythm, low blood pressure, dizziness, chest pain; or difficulty breathing. Do not discontinue the medication without consulting a doctor.
Amlodipine + MetoprololCeritinib
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Taking Ceritinib with Amlodipine and Metoprolol can slow the heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Amlodipine and Metoprolol with Ceritinib, but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience any dizziness, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
Amlodipine + MetoprololDolasetron
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Using Dolasetron together with Amlodipine can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amlodipine and Dolasetron, but it can be taken if prescribed by a doctor. If you experience dizziness, heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
Amlodipine + MetoprololAminophylline
Severe
How does the drug interact with Amlopin-M 25 Tablet:
Co-administration of Aminophylline with Amlodipine and Metoprolol together can make Metoprolol less effective and increase the effects of Aminophylline.

How to manage the interaction:
Taking Aminophylline with Amlodipine and Metoprolol may lead to an interaction, it can be taken only if a doctor has advised it. If you experience vomiting, sleeplessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

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FAQs

Amlopin-M 25 Tablet is used to treat high blood pressure/hypertension and‚ angina pectoris.
Amlopin-M 25 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.
Do not stop taking Amlopin-M 25 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Amlopin-M 25 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Amlopin-M 25 Tablet .
Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Amlopin-M 25 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Amlopin-M 25 Tablet if you suffer from this condition.
Light-headedness could be a side-effect of Amlopin-M 25 Tablet . It occurs due to low blood pressure, leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Amlopin-M 25 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.
Amlopin-M 25 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Amlopin-M 25 Tablet on fertility. Please consult your doctor in case of any concerns.
Amlopin-M 25 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.
Change your lifestyle in a few essential ways to control your blood pressure. Start by moving; on most days of the week, try to get in at least 30 minutes of exercise, such as swimming or brisk walking. Next, have a well-balanced diet that is rich in fruits, vegetables, lean protein, and whole foods while being low in processed foods, salt, and bad fats. Keep an eye on your weight, drink moderately, and learn stress-reduction techniques like deep breathing or meditation. Aim for 7-8 hours of sleep per night and stay hydrated throughout the day. Try to give up smoking and limit your daily caffeine consumption to one cup of coffee. Don't forget to consult your healthcare practitioner before making any significant adjustments.
Yes. It is effective. Even so, the effectiveness of Amlopin-M 25 Tablet depends on various factors, such as the individual's medical history, dosage, and response to the medication. It's important to consult with a healthcare professional to determine if this medication is appropriate for your specific condition and to monitor its effectiveness.
Amlopin-M 25 Tablet is not typically considered a habit-forming medication.
Take Amlopin-M 25 Tablet as directed. Swallow the tablet whole with water, and take it at the same time each day. Don't crush or chew the tablet. Continue taking the medication even if you feel well, as it helps control your condition. If you need to stop, consult your doctor first to avoid any issues. Regularly check your blood pressure and heart rate, and follow up with your doctor to adjust your dosage as needed.
Amlopin-M 25 Tablet should be stored in a cool,and dry place away from sunlight. Keep Amlopin-M 25 Tablet out of the sight and reach of children.
It is not advisable to smoke when taking Amlopin-M 25 Tablet . Smoking may lessen this medication's effectiveness and heart-healthy improvement effects. In addition to improving your general health, quitting smoking will help your medication function better.
Amlopin-M 25 Tablet may interact with other medications. Before taking it, consult your doctor to ensure safe use, especially if you're already taking other medications. Never combine it with other medications without your doctor's guidance.
Before taking any medication, including Amlopin-M 25 Tablet , be sure to tell your doctor if you have any allergies or health conditions or are pregnant or breastfeeding. This will help ensure your safety and avoid any potential interactions or harm.
Amlopin-M 25 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Metoprolol Succinate + Amlodipine Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Electronic Medicines Compendium (EMC). Pil.5199 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.5701 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. DrugBank Online. Db09231 Clinical & Chemical Summary. Edmonton, AB: DrugBank; 2026. [Accessed on 02 Jun. 2026] Check here
  5. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026] Check here
  6. Amlodipine besylate. 1987. [Accessed on 11 Apr. 2019] Check here
  7. Metoprolol succinate. 1992. [Accessed on 11 Apr. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.
Other Info - AML0140

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