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मैकलेओड्स फार्मास्युटिकल्स लिमिटेड
उपभोग प्रकार :
मौखिक
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वापसी योग्य नहीं
इसके बाद या बाद में समाप्त होता है :
Dec-28
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Drug-Drug Interactions
Critical
HydrochlorothiazideDofetilide
Critical
Drug-Drug Interactions
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Critical
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Taking Cisapride and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Pepnipril-H 2.5mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Taking Cisapride and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Cisapride and Pepnipril-H 2.5mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Taking Dofetilide and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Pepnipril-H 2.5mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Taking Dofetilide and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Combining Dofetilide and Pepnipril-H 2.5mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Taking aliskiren together with Pepnipril-H 2.5mg/12.5mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.
How to manage the interaction:
Taking Pepnipril-H 2.5mg/12.5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
Taking aliskiren together with Pepnipril-H 2.5mg/12.5mg Tablet may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.
How to manage the interaction:
Taking Pepnipril-H 2.5mg/12.5mg Tablet with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
The combined use of Tizanidine and Pepnipril-H 2.5mg/12.5mg Tablet can have additive effects in lowering your blood pressure.
How to manage the interaction:
Taking Tizanidine and Pepnipril-H 2.5mg/12.5mg Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
The combined use of Tizanidine and Pepnipril-H 2.5mg/12.5mg Tablet can have additive effects in lowering your blood pressure.
How to manage the interaction:
Taking Tizanidine and Pepnipril-H 2.5mg/12.5mg Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Taking Ziprasidone and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Ziprasidone and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
Taking Ziprasidone and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Ziprasidone and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Co-administration of Arsenic trioxide and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Arsenic trioxide and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Arsenic trioxide and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Arsenic trioxide and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Co-administration of Dronedarone and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of severe irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Dronedarone and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Dronedarone and Pepnipril-H 2.5mg/12.5mg Tablet can increase the risk of severe irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Dronedarone and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Coadministration of Amiodarone together with Pepnipril-H 2.5mg/12.5mg Tablet may raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Even though Amiodarone and Pepnipril-H 2.5mg/12.5mg Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
Coadministration of Amiodarone together with Pepnipril-H 2.5mg/12.5mg Tablet may raise the risk of an abnormal heart rhythm.
How to manage the interaction:
Even though Amiodarone and Pepnipril-H 2.5mg/12.5mg Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Coadministration of Lithium and Pepnipril-H 2.5mg/12.5mg Tablet can increase the effects of lithium.
How to manage the interaction:
Taking Lithium and Pepnipril-H 2.5mg/12.5mg Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of Lithium and Pepnipril-H 2.5mg/12.5mg Tablet can increase the effects of lithium.
How to manage the interaction:
Taking Lithium and Pepnipril-H 2.5mg/12.5mg Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDolasetron
Severe
How does the drug interact with Pepnipril-H 2.5mg/12.5mg Tablet:
Co-administration of Dolasetron and Pepnipril-H 2.5mg/12.5mg Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Dolasetron and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Dolasetron and Pepnipril-H 2.5mg/12.5mg Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.
How to manage the interaction:
Taking Dolasetron and Pepnipril-H 2.5mg/12.5mg Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Drug-Food Interactions
HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate
Drug-Food Interactions
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HYDROCHLOROTHIAZIDE-12.5MG+RAMIPRIL-2.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Consumption of high potassium diet with Pepnipril-H 2.5mg/12.5mg Tablet can cause high levels of potassium in blood. Avoid high potassium diet while being treated with Pepnipril-H 2.5mg/12.5mg Tablet.
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Tomatoes, Sweet Potatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt
How to manage the interaction:
Consumption of high potassium diet with Pepnipril-H 2.5mg/12.5mg Tablet can cause high levels of potassium in blood. Avoid high potassium diet while being treated with Pepnipril-H 2.5mg/12.5mg Tablet.
All Substitutes & Brand Comparisons
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शराब
असुरक्षित
यदि शराब के साथ लिया जाता है तो पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट हाइपोटेंसिव (निम्न रक्तचाप) प्रभाव को बढ़ा सकता है। बेहतर सलाह के लिए, आपको अपने डॉक्टर से परामर्श लेना चाहिए कि क्या आप शराब के साथ पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट ले सकते हैं।
गर्भावस्था
असुरक्षित
पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट या किसी भी एसीई इनहिबिटर (रमीप्रिल) का उपयोग आमतौर पर गर्भावस्था के दूसरे और तीसरे तिमाही के दौरान contraindicated है। इससे विकासशील भ्रूण को नुकसान हो सकता है। इसलिए, आपको पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट का उपयोग करने से पहले हमेशा अपने डॉक्टर से सलाह लेनी चाहिए।
स्तनपान
सावधानी
स्तनपान के चरण के दौरान पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट के उपयोग की अनुशंसा नहीं की जाती है।
ड्राइविंग
असुरक्षित
सावधानी से गाड़ी चलाएँ, पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट धुंधली दृष्टि का कारण बन सकता है, और चक्कर आना या थकान हो सकती है।
जिगर
सावधानी
पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट लेते समय लीवर एंजाइम (जैसे बिलीरुबिन) में दुर्लभ वृद्धि देखी गई है, इसलिए इसे सावधानी के साथ लिया जाना चाहिए। यदि आपके लीवर के रोगों/स्थितियों का इतिहास है, तो आपके डॉक्टर द्वारा खुराक को समायोजित करना पड़ सकता है।
गुर्दा
सावधानी
विशेष रूप से गुर्दे की गंभीर बीमारी के मामले में पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट सावधानी के साथ लिया जाना चाहिए। आपके डॉक्टर द्वारा खुराक को समायोजित करना पड़ सकता है। हेमोडायलिसिस की स्थिति में पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट सावधानी के साथ दिया जाना चाहिए।
बच्चे
सावधानी
बच्चों के लिए पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट की सिफारिश नहीं की जाती है। दुनिया भर में सक्षम अधिकारियों द्वारा बच्चों पर इस दवा के सीमित परीक्षण के कारण बच्चों में पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट की सुरक्षा और प्रभावशीलता स्थापित नहीं की गई है। यदि आवश्यक हो, तो आपका डॉक्टर यह तय करेगा कि पेपनिप्रिल-एच 2.5mg/12.5mg टैबलेट देना है या नहीं।
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