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Perinorm Syrup is used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, it is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus. It contains Metoclopramide, which works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helping in preventing nausea and vomiting. In some cases, it may cause common side effects such as restlessness, fatigue, drowsiness, diarrhoea, weakness, and lassitude (lack of energy). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Side effects of Perinorm Syrup 60 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

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Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Perinorm Syrup 60 ml:
Using Perinorm Syrup 60 ml with Paroxetine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Perinorm Syrup 60 ml with Paroxetine is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Perinorm Syrup 60 ml:
Coadministration of Perinorm Syrup 60 ml with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Perinorm Syrup 60 ml with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perinorm Syrup 60 ml:
Co-administration of Perinorm Syrup 60 ml with Amoxapine can increase the risk of side effects.

How to manage the interaction:
Taking Perinorm Syrup 60 ml with Amoxapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perinorm Syrup 60 ml:
Coadministration of Fluvoxamine with Perinorm Syrup 60 ml increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Fluvoxamine with Perinorm Syrup 60 ml is not recommended, as it can lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Perinorm Syrup 60 ml:
Coadministration of Tetrabenazine and Perinorm Syrup 60 ml can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Tetrabenazine and Perinorm Syrup 60 ml together is not recommended as it can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perinorm Syrup 60 ml:
Coadministration of Perinorm Syrup 60 ml with Trazodone can rarely increase serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Perinorm Syrup 60 ml with Trazodone is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any symptoms like dizziness, fever, excessive sweating, shivering, blurred vision, muscle stiffness, stomach cramps, nausea, vomiting, or diarrhoea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perinorm Syrup 60 ml:
The combination of Lurasidone and Perinorm Syrup 60 ml may result in significantly increased Lurasidone blood levels. This may raise the possibility of undesirable consequences such as Parkinson's disease. (It is a neurological condition that causes uncontrollable movements)and Tardive dyskinesia (uncontrollable movements, particularly of the lower face).

How to manage the interaction:
Lurasidone and Perinorm Syrup 60 ml is not recommended, as they may interact, but can be used if a doctor prescribes them. Consult a doctor if you have muscle spasms, or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning, tongue thrusting, teeth clenching, jaw twitching, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without visiting a doctor.
How does the drug interact with Perinorm Syrup 60 ml:
Co-administration of Perinorm Syrup 60 ml with Aripiprazole can increase the risk of side effects.

How to manage the interaction:
Taking Aripiprazole with Perinorm Syrup 60 ml is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Perinorm Syrup 60 ml:
Co-administration of Perinorm Syrup 60 ml with Risperidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Risperidone with Perinorm Syrup 60 ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Perinorm Syrup 60 ml:
Coadministration of Perinorm Syrup 60 ml with Promethazine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Promethazine with Perinorm Syrup 60 ml is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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