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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Reglan Syrup is used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, it is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus. It contains Metoclopramide, which works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helping in preventing nausea and vomiting. In some cases, it may cause common side effects such as restlessness, fatigue, drowsiness, diarrhoea, weakness, and lassitude (lack of energy). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

METOCLOPRAMIDE-5MG

Manufacturer/Marketer :

Oaknet Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Reglan Syrup

Reglan Syrup is used to prevent nausea and vomiting caused by chemotherapy, radiotherapy, and which might occur after migraine. Additionally, Reglan Syrup is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus.

Reglan Syrup contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helping in preventing nausea and vomiting.

In some cases, Reglan Syrup may cause common side effects such as restlessness, fatigue, drowsiness, diarrhoea, weakness, and lassitude (lack of energy). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not take Reglan Syrup for more than 3 months as it might increase the risk of tardive dyskinesia (movement disorder). Consult your doctor before taking Reglan Syrup if you are pregnant or breastfeeding. Reglan Syrup may cause drowsiness and dizziness, so avoid driving until you know how Reglan Syrup affects you. Avoid consuming alcohol along with Reglan Syrup as it could lead to increased drowsiness. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Reglan Syrup

Reglan Syrup is used in the prevention of Nausea, Vomiting, gastroesophageal reflux disease (GERD), and diabetic gastroparesis (delayed gastric emptying in people with diabetes). The detailed uses of Reglan Syrup are as follows:

  • Nausea Relief: Reglan Syrup is frequently used to treat nausea brought on by a number of illnesses, such as those brought on by stress, anxiety, or digestive problems.
  • Control of Vomiting: The suspension works well to stop and control vomiting, particularly in individuals who are having chemotherapy, surgery, or motion sickness.
  • Gastrointestinal Disorders: It can be used to alleviate the symptoms of illnesses like gastritis or gastroenteritis and cure nausea associated with gastrointestinal disorders.

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Directions for Use

  • Reglan Syrup can be taken 30 minutes before food, preferably at bedtime or as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication
  • Swallow Reglan Syrup as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

Reglan Syrup belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy and radiotherapy, which might occur after migraines. Additionally, Reglan Syrup is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus. Reglan Syrup contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also affects the dopamine receptor in the brain and gut, thereby helps in preventing nausea and vomiting.

How Reglan Syrup Works

Reglan Syrup contains ‘metoclopramide’ that works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight
Side effects of Reglan Syrup 60 ml
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

What if I have taken an overdose of Reglan Syrup

Do not take more than the prescribed dose of Reglan Syrup as it may cause overdose. The symptoms of overdose include tremor, muscle spasms, shaking, confusion, drowsiness or hallucinations. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Reglan Syrup if you are allergic to any of its contents; if you have bleeding or obstruction in the stomach, tardive dyskinesia (movement disorder), pheochromocytoma (tumour in the adrenal glands), or epilepsy. Talk to your doctor before taking Reglan Syrup if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, liver or kidney problems, Parkinson’s disease, methaemoglobinaemia; if you are taking levodopa or if you have gastrointestinal surgery in the last 3-4days. Do not take Reglan Syrup for more than three months as it might increase the risk of tardive dyskinesia; the risk increases if you are older, especially if you are an older woman or if you have diabetes. Consult your doctor immediately if you cannot stop or control movements like shaking your arms and legs, blinking and moving your eyes, sticking out the tongue, frowning, lip-smacking, chewing, or puckering up the mouth.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Amoxapine can increase the risk of side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Amoxapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Citalopram with Reglan Syrup 60 ml can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Citalopram with Reglan Syrup 60 ml is generally avoided as it can possibly result in an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml with Venlafaxine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Venlafaxine together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml with quetiapine can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Quetiapine is generally avoided as it can possibly result in an interaction. They can be taken together if advised by your doctor. However, contact a doctor if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Taking Reglan Syrup 60 ml with Ziprasidone can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience lip-smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Co-administration of Reglan Syrup 60 ml with Clozapine can increase the risk of side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Clozapine is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml with duloxetine increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Reglan Syrup 60 ml with Duloxetine is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Fluvoxamine with Reglan Syrup 60 ml increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Fluvoxamine with Reglan Syrup 60 ml is not recommended, as it can lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Reglan Syrup 60 ml:
Coadministration of Reglan Syrup 60 ml and prochlorperazine can increase the risk of side effects.

How to manage the interaction:
Taking Reglan Syrup 60 ml with Prochlorperazine together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Reglan Syrup 60 ml:
Using Reglan Syrup 60 ml with Paroxetine can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhoea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Taking Reglan Syrup 60 ml with Paroxetine is not recommended, as it can possibly lead to an interaction, it can be taken if prescribed by your doctor. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Drink fluids to stay hydrated.
  • Avoid solid foods until vomiting stops.
  • Avoid foods that might cause stomach upset.
  • Take ample rest. Avoid any activity immediately after eating.
  • Consume plain, light foods such as bread and biscuits.
  • Avoid food with strong flavours and fried food.
  • Ginger tea might help in proper digestion.

Habit Forming

No

Therapeutic Class

[ANTIEMETICS, GASTROPROKINETIC AGENTS]

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Alcohol

Safe if prescribed

Avoid consumption of alcohol while taking Reglan Syrup as it may make some side effects worse such as increased sleepiness and drowsiness.

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Pregnancy

Consult your doctor

Consult your doctor before taking Reglan Syrup if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking Reglan Syrup if you are breastfeeding.

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Driving

Safe if prescribed

Reglan Syrup may cause dizziness, drowsiness and fatigue. Do not drive or operate machinery until you know how Reglan Syrup affects you.

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Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Reglan Syrup if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Reglan Syrup if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Reglan Syrup are not recommended for children due to the risk of tardive dyskinesia, extrapyramidal symptoms as well as risk of methemoglobinemia in neonates.

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Heart

Reglan Syrup should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Reglan Syrup.

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Geriatrics

Consult your doctor

Reglan Syrup should be administered with caution in elderly patients. If you have any concerns, please consult your doctor.

FAQs

Reglan Syrup belongs to a group of medicines called anti-emetics and prokinetic agents used to prevent nausea and vomiting caused by chemotherapy and radiotherapy, which might occur after migraines. Reglan Syrup is also used to treat gastro-oesophageal reflux disease (GERD), diabetic gastroparesis (delayed gastric emptying in people with diabetes), heartburn, ulcers and sores in the oesophagus.

Reglan Syrup works by increasing the motility of the upper gastrointestinal tract; this allows faster transit of food and reduces the symptoms of GERD and gastric emptying. It also works on the part of the brain that controls vomiting, thereby helps in preventing nausea and vomiting.

Take Reglan Syrup only for as long as the doctor has prescribed it for you. Do not take Reglan Syrup for more than three months as it might increase the risk of tardive dyskinesia (movement disorder), which is often irreversible. The risk of developing tardive dyskinesia increases with the total dosage and duration of treatment.

Diarrhoea might be a side-effect of Reglan Syrup. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.

Maintain a minimum gap of 6 hours between each dose. Do not take another dose of Reglan Syrup even in case of vomiting and rejection of dose to avoid an overdose.

Reglan Syrup may cause uncontrollable movements such as shaking, tics, twisting movements, muscle stiffness and rigidity. Consult your doctor if you experience these symptoms.

Take Reglan Syrup 30 minutes before food, preferably at bedtime or as advised by the doctor.

Before starting Reglan Syrup, inform the doctor if you have heart problems, diabetes, depression, high blood pressure, breast cancer, seizures, liver or kidney problems, Parkinson's disease, methemoglobinemia (blood disorder); if you are taking levodopa or if you have had gastrointestinal surgery in the last 3-4 days.

No, Reglan Syrup should not be taken after meals. It works best when taken on an empty stomach.

Reglan Syrup is not known to cause constipation. Drink enough fluids and eat fibre-rich food if you have constipation. Consult the doctor if the condition persists or worsens.

Reglan Syrup is not indicated for the treatment of morning sickness. It is used to treat nausea, vomiting, gastroesophageal reflux disease (GERD), and diabetic gastroparesis (delayed gastric emptying in people with diabetes). Talk to the doctor if you have morning sickness; the doctor will prescribe appropriate medicine based on your condition.

Reglan Syrup can be taken with ranitidine if prescribed by the doctor. No interaction has been reported between both these medicines.

Reglan Syrup may cause side effects such as restlessness, fatigue, drowsiness, diarrhoea, weakness, and lassitude (lack of energy). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

64, First Floor, 3Rd Cross, Venkata Ramaiah Layout, Ramamurthy Nagar Main Road , Banaswadi , Bangalore - 560043, India
Other Info - REG0136

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