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  3. Provagen 50 mg Injection 1 ml

Provagen 50 mg Injection 1 ml, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Provagen 50 mg Injection 1 ml is used in the treatment of dysfunctional uterine bleeding threatened abortion, and amenorrhoea. It is also used in the maintenance of early pregnancy. This medicine contains progesterone, a female hormone which helps increase the progesterone levels in the body. Common side effects include injection site reactions, rash or any other allergy, changes in the breast, darkening of facial skin, scalp hair loss, coarsening of hair in abnormal regions.

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Side effects of Provagen 50mg/1ml Inj
  • Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
  • Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
  • Eat a balanced diet and avoid foods high in estrogen-like compounds.
  • Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Mood swings can be managed but cannot be controlled. Therefore, spending time in nature can help you feel light and improve your mood.
  • Practice meditation, deep breathing and do regular exercise that can positively affect your mood. Also helps in processing the situation before responding to it.
  • Food has direct impact on mood. Therefore, eat foods that are less processed and reduce sugar intake.
  • Consult your doctor if the mood swings are uncontrollable or unmanageable.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
  • Talk to your doctor to determine the underlying cause of bleeding between periods and discuss appropriate treatment options.
  • To avoid infection, use sanitary items and change them frequently as part of proper hygiene.
  • Engage in moderate exercise, like walking, cycling, or swimming, to help regulate your menstrual cycle.
  • To lower the chance of hormonal imbalances and intermenstrual bleeding, maintain a healthy weight.
  • Apply a warm compress to the lower abdomen to ease cramps.
  • Seek medical attention if you experience heavy or prolonged bleeding between periods.

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
ProgesteroneMorphine
Severe

Drug-Drug Interactions

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ProgesteroneEdoxaban
Severe
How does the drug interact with Provagen 50mg/1ml Inj:
When Provagen 50mg/1ml Inj is taken with Edoxaban, may increase the blood levels of Edoxaban which increases the risk of serious bleeding complications.

How to manage the interaction:
Although taking Provagen 50mg/1ml Inj and edoxaban together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, you should consult a doctor. Do not discontinue any medications without a doctor's advice.
ProgesteroneMorphine
Severe
How does the drug interact with Provagen 50mg/1ml Inj:
Co-administration of Provagen 50mg/1ml Inj with Morphine may increase the blood levels and side effects of Morphine.

How to manage the interaction:
Co-administration of Morphine with Provagen 50mg/1ml Inj can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ProgesteroneVenetoclax
Severe
How does the drug interact with Provagen 50mg/1ml Inj:
Co-administration of Provagen 50mg/1ml Inj with Venetoclax may increase the blood levels of Venetoclax which increases the risk of side effects.

How to manage the interaction:
Although taking Provagen 50mg/1ml Inj and Venetoclax together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms such as fatigue, nausea, vomiting, diarrhea, and infections, it is advised to consult a doctor. Without consulting a doctor, never stop taking any drugs.
ProgesteroneTirzepatide
Moderate
How does the drug interact with Provagen 50mg/1ml Inj:
Provagen 50mg/1ml Inj may interfere with blood glucose control and reduce the effectiveness of tirzepatide and other diabetic medications.

How to manage the interaction:
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Monitor your blood sugar levels closely.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 11:31 AM IST

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